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2 hits found for TAR DNA-binding protein 43

SASDV74 – ...DNA-binding protein 43 (TDP-43)

TAR DNA-binding protein 43 experimental SAS data
OTHER model
Sample: TAR DNA-binding protein 43 monomer, 9 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl, 150 mM NaCl, 1 mM DTT, 3% glycerol, pH: 8.5
Experiment: SAXS data collected at BL38B1, SPring-8 on 2024 May 29
...43 reveals the effects of phosphorylation in N-terminal domain on self-association Communications Chemistry 8(1) (2025)
Sasaki D, Tenda M, Sohma Y
RgGuinier 1.4 nm
Dmax 4.3 nm
VolumePorod 15 nm3

SASDXL8 – ...protein bound to GT-repeat DNA Oligo: TDP-43 (TAR DNA-binding protein 43)

TAR DNA-binding protein 43 experimental SAS data
TAR DNA-binding protein 43 Kratky plot
Sample: TAR DNA-binding protein 43 monomer, 63 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 100 mM KCl, 2 mM TCEP, pH: 7.6
Experiment: SAXS data collected at SWING, SOLEIL on 2022 Nov 30
...43/RNA complex formation to disease-linked TDP-43 aggregation through a structural and cellular approach. Nat Commun (2026)
Feng Y, Joshi V, Pankivskyi S, Clément MJ, Rengifo-Gonzalez JC, Thureau A, Pastré D, Bouhss A
RgGuinier 4.0 nm
Dmax 16.5 nm
VolumePorod 135 nm3