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15 hits found for Apolipoprotein E3

SASDGD7 – Apolipoprotein E3 bound to 330 µg/mL heparin

Apolipoprotein E3Heparin experimental SAS data
Apolipoprotein E3 Heparin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Heparin monomer, 15 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 7.3 nm
Dmax 25.9 nm

SASDGE7 – Apolipoprotein E3 bound to 110 µg/mL heparin

Apolipoprotein E3Heparin experimental SAS data
Apolipoprotein E3 Heparin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Heparin monomer, 15 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 7.5 nm
Dmax 25.8 nm

SASDGF7 – Apolipoprotein E3 bound to 37 µg/mL heparin

Apolipoprotein E3Heparin experimental SAS data
Apolipoprotein E3 Heparin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Heparin monomer, 15 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 6.9 nm
Dmax 23.9 nm

SASDGG7 – Apolipoprotein E3 bound to 12 µg/mL heparin

Apolipoprotein E3Heparin experimental SAS data
Apolipoprotein E3 Heparin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Heparin monomer, 15 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 6.5 nm
Dmax 22.0 nm

SASDGH7 – Apolipoprotein E3 bound to 4 µg/mL heparin

Apolipoprotein E3Heparin experimental SAS data
Apolipoprotein E3 Heparin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Heparin monomer, 15 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 6.3 nm
Dmax 20.8 nm

SASDD98 – Apolipoprotein E3

Apolipoprotein E3 experimental SAS data
Apolipoprotein E3 Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 300 mM NaCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2017 Nov 29
...Apolipoprotein E4 as the major risk factor for late onset Alzheimer's disease. J Mol Biol (2019)
Raulin AC, Kraft L, Al-Hilaly YK, Xue WF, McGeehan JE, Atack JR, Serpell L
RgGuinier 5.7 nm
Dmax 19.5 nm
VolumePorod 410 nm3

SASDGA8 – Apolipoprotein E3 bound to 330 µM Suramin

Apolipoprotein E3Suramin experimental SAS data
Apolipoprotein E3 Suramin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 5.2 nm
Dmax 18.6 nm

SASDGB8 – Apolipoprotein E3 bound to 110 µM Suramin

Apolipoprotein E3Suramin experimental SAS data
Apolipoprotein E3 Suramin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 5.6 nm
Dmax 19.1 nm

SASDGC8 – Apolipoprotein E3 bound to 37 µM Suramin

Apolipoprotein E3Suramin experimental SAS data
Apolipoprotein E3 Suramin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 6.0 nm
Dmax 20.3 nm

SASDGD8 – Apolipoprotein E3 bound to 12 µM Suramin

Apolipoprotein E3Suramin experimental SAS data
Apolipoprotein E3 Suramin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 6.1 nm
Dmax 20.0 nm

SASDGE8 – Apolipoprotein E3 bound to 4 µM Suramin

Apolipoprotein E3Suramin experimental SAS data
Apolipoprotein E3 Suramin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 6.2 nm
Dmax 20.1 nm

SASDG49 – Apolipoprotein E3

Apolipoprotein E3 experimental SAS data
Apolipoprotein E3 Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 6.1 nm
Dmax 20.6 nm

SASDGC9 – Apolipoprotein E3 (SEC-SAXS)

Apolipoprotein E3 experimental SAS data
Apolipoprotein E3 Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 5.8 nm
Dmax 20.0 nm

SASDGD9 – Apolipoprotein E3 bound to 1 mg/mL heparin (SEC-SAXS)

Apolipoprotein E3Heparin experimental SAS data
Apolipoprotein E3 Heparin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Heparin monomer, 15 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 6.1 nm
Dmax 21.3 nm

SASDGE9 – Apolipoprotein E3 bound to 1 mM Suramin (SEC-SAXS)

Apolipoprotein E3Suramin experimental SAS data
Apolipoprotein E3 Suramin Kratky plot
Sample: Apolipoprotein E3 tetramer, 139 kDa Homo sapiens protein
Suramin monomer, 1 kDa
Buffer: 20 mM HEPES, 300 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 3
Apolipoprotein E project
Lucas Kraft
RgGuinier 5.1 nm
Dmax 19.3 nm