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7 hits found for Haataja

SASDFD3 – Filamin A Ig-like domains 4-6 (FLNa4-6)

Filamin A Ig-like domains 4-6 experimental SAS data
DAMFILT model
Sample: Filamin A Ig-like domains 4-6 monomer, 32 kDa Homo sapiens protein
Buffer: 20 mM Tris, 100 mM NaCl, 1 mM DTT, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2017 Feb 10
Critical Structural Defects Explain Filamin A Mutations Causing Mitral Valve Dysplasia Biophysical Journal (2019)
Haataja T, Capoulade R, Lecointe S, Hellman M, Merot J, Permi P, Pentikäinen U
RgGuinier 2.7 nm
Dmax 9.5 nm
VolumePorod 41 nm3

SASDFE3 – Filamin A Ig-like domains 4-6, V711D mutant (FLNa4-6 V711D) at 4 mg/ml

Filamin A Ig-like domains 4-6, V711D mutation experimental SAS data
Filamin A Ig-like domains 4-6, V711D mutation Kratky plot
Sample: Filamin A Ig-like domains 4-6, V711D mutation monomer, 32 kDa Homo sapiens protein
Buffer: 20 mM Tris, 100 mM NaCl, 1 mM DTT, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2017 Feb 10
Critical Structural Defects Explain Filamin A Mutations Causing Mitral Valve Dysplasia Biophysical Journal (2019)
Haataja T, Capoulade R, Lecointe S, Hellman M, Merot J, Permi P, Pentikäinen U
RgGuinier 4.1 nm
Dmax 15.0 nm
VolumePorod 64 nm3

SASDFF3 – Filamin A Ig-like domains 4-6, V711D mutant (FLNa4-6 V711D) at 2 mg/ml

Filamin A Ig-like domains 4-6, V711D mutation experimental SAS data
Filamin A Ig-like domains 4-6, V711D mutation Kratky plot
Sample: Filamin A Ig-like domains 4-6, V711D mutation monomer, 32 kDa Homo sapiens protein
Buffer: 20 mM Tris, 100 mM NaCl, 1 mM DTT, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2017 Feb 10
Critical Structural Defects Explain Filamin A Mutations Causing Mitral Valve Dysplasia Biophysical Journal (2019)
Haataja T, Capoulade R, Lecointe S, Hellman M, Merot J, Permi P, Pentikäinen U
RgGuinier 4.0 nm
Dmax 14.8 nm
VolumePorod 57 nm3

SASDFG3 – Filamin A Ig-like domains 4-6, H743P mutant (FLNa4-6 H743P) at 4 mg/ml

Filamin A Ig-like domains 4-6, H743P mutation experimental SAS data
Filamin A Ig-like domains 4-6, H743P mutation Kratky plot
Sample: Filamin A Ig-like domains 4-6, H743P mutation monomer, 31 kDa Homo sapiens protein
Buffer: 20 mM Tris, 100 mM NaCl, 1 mM DTT, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2017 Feb 10
Critical Structural Defects Explain Filamin A Mutations Causing Mitral Valve Dysplasia Biophysical Journal (2019)
Haataja T, Capoulade R, Lecointe S, Hellman M, Merot J, Permi P, Pentikäinen U
RgGuinier 4.3 nm
Dmax 16.0 nm
VolumePorod 70 nm3

SASDFH3 – Filamin A Ig-like domains 4-6, H743P mutant (FLNa4-6 H743P) at 2 mg/ml

Filamin A Ig-like domains 4-6, H743P mutation experimental SAS data
Filamin A Ig-like domains 4-6, H743P mutation Kratky plot
Sample: Filamin A Ig-like domains 4-6, H743P mutation monomer, 31 kDa Homo sapiens protein
Buffer: 20 mM Tris, 100 mM NaCl, 1 mM DTT, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2017 Feb 10
Critical Structural Defects Explain Filamin A Mutations Causing Mitral Valve Dysplasia Biophysical Journal (2019)
Haataja T, Capoulade R, Lecointe S, Hellman M, Merot J, Permi P, Pentikäinen U
RgGuinier 4.0 nm
Dmax 15.3 nm
VolumePorod 60 nm3

SASDEP7 – Filamin A Ig-like domains 3-5 P637Q mutant (FLNa3-5 P637Q)

Filamin A Ig.like domains 3-5 P637Q mutant experimental SAS data
PDB model
Sample: Filamin A Ig.like domains 3-5 P637Q mutant monomer, 31 kDa Homo sapiens protein
Buffer: 20 mM Tris, 100 mM NaCl, 1 mM DTT, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2017 Feb 10
Non-syndromic Mitral Valve Dysplasia Mutation Changes the Force Resilience and Interaction of Human Filamin A. Structure (2018)
Haataja TJK, Bernardi RC, Lecointe S, Capoulade R, Merot J, Pentikäinen U
RgGuinier 2.2 nm
Dmax 7.4 nm
VolumePorod 39 nm3

SASDEQ7 – Filamin A Ig-like domains 3-5 (FLNa3-5)

Filamin A Ig-like domains 3-5 experimental SAS data
PDB model
Sample: Filamin A Ig-like domains 3-5 monomer, 31 kDa Homo sapiens protein
Buffer: 20 mM Tris, 100 mM NaCl, 1 mM DTT, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2017 Feb 10
Non-syndromic Mitral Valve Dysplasia Mutation Changes the Force Resilience and Interaction of Human Filamin A. Structure (2018)
Haataja TJK, Bernardi RC, Lecointe S, Capoulade R, Merot J, Pentikäinen U
RgGuinier 2.2 nm
Dmax 7.3 nm
VolumePorod 39 nm3