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3 hits found for Heat shock protein 70

SASDDN6 – ...heat shock 70 kDa protein 1, Hsp70 (Hspa1a) T204A mutant dimer, in the presence of ATP

Heat shock 70 kDa protein 1 experimental SAS data
MODELLER model
Sample: Heat shock 70 kDa protein 1 dimer, 147 kDa Homo sapiens protein
Buffer: 50mM HEPES, 150mM KCH3COO, 2mM MgCl2, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-1000, CEITEC on 2018 Feb 20
...70 has a high propensity to form ATP-dependent antiparallel dimers that are differentially regulated by co-chaperone binding. Mol Cell Proteomics (2018)
Trcka F, Durech M, Vankova P, Chmelik J, Martinkova V, Hausner J, Kadek A, Marcoux J, Klumpler T, Vojtesek B, Muller P, Man P
RgGuinier 4.0 nm
Dmax 11.6 nm
VolumePorod 248 nm3

SASDBY6 – ...heat shock protein 70 (LbmtHSP70)

Mitochondrial heat shock protein 70 experimental SAS data
DAMMIN model
Sample: ...heat shock protein 70 monomer, 71 kDa Leishmania braziliensis protein
Buffer: 25 mM Tris-HCl, 50 mM NacL, 5 mM KCl, 5 mM sodium phosphate, 2 mM B-mercaptoethanol, pH: 7.5
Experiment: SAXS data collected at SAXS1 Beamline, Brazilian Synchrotron Light Laboratory on 2012 Jun 22
...70: Similarities and dissimilarities to human orthologues. Arch Biochem Biophys 613:43-52 (2017)
Dores-Silva PR, Nishimura LS, Kiraly VT, Borges JC
RgGuinier 3.6 nm
Dmax 14.0 nm
VolumePorod 118 nm3

SASDHU5Heat shock protein 70 (PfHSP70-1)

Heat shock protein 70Peptide experimental SAS data
DAMFILT model
Sample: Heat shock protein 70 monomer, 74 kDa Plasmodium falciparum protein
Peptide monomer, 1 kDa synthetic construct protein
Buffer: 50mM Tris, 5mM MgCl2, 500mM KCl, 5mM Bme, 5% glycerol, pH: 8
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2019 Oct 24
...70-1 and PfHSP40 chaperone pair gives an edge over human orthologs in chaperone-assisted protein folding. Biochem J 477(18):3625-3643 (2020)
Anas M, Shukla A, Tripathi A, Kumari V, Prakash C, Nag P, Kumar LS, Sharma SK, Ramachandran R, Kumar N
RgGuinier 5.3 nm
Dmax 16.6 nm
VolumePorod 450 nm3