SASBDB entries for UniProt ID:

SASDU75 – Calcium/calmodulin-dependent protein kinase type II alpha (CaMKIIα) 6x hub domain with 5-HDC

UniProt ID: Q9UQM7 (345-475) Calcium/calmodulin-dependent protein kinase type II subunit alpha (T354N, E355Q, T412N, I414M, I464H, F467M)

UniProt ID: None (None-None) 5-hydroxydiclofenac
Calcium/calmodulin-dependent protein kinase type II subunit alpha (T354N, E355Q, T412N, I414M, I464H, F467M)5-hydroxydiclofenac experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (T354N, E355Q, T412N, I414M, I464H, F467M) 5-hydroxydiclofenac Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (T354N, E355Q, T412N, I414M, I464H, F467M) 14-mer, 217 kDa Homo sapiens protein
5-hydroxydiclofenac monomer, 0 kDa
Buffer: 20 mM MES, 150 mM NaCl, 1 mM DTT, 100 µM 5-HDC, pH: 6
Experiment: SAXS data collected at Xenocs BioXolver L with MetalJet, University of Copenhagen, Department of Drug Design and Pharmacology on 2020 Nov 19
Ligand‐induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity Protein Science 33(10) (2024)
Narayanan D, Larsen A, Gauger S, Adafia R, Hammershøi R, Hamborg L, Bruus‐Jensen J, Griem‐Krey N, Gee C, Frølund B, Stratton M, Kuriyan J, Kastrup J, Langkilde A, Wellendorph P, Solbak S
RgGuinier 4.7 nm
Dmax 18.5 nm
VolumePorod 366 nm3

SASDU85 – Wild-type phosphoserine phosphatase RsbU dimer

UniProt ID: P40399 (1-335) Phosphoserine phosphatase RsbU
Phosphoserine phosphatase RsbU experimental SAS data
MULTIFOXS model
Sample: Phosphoserine phosphatase RsbU dimer, 77 kDa Bacillus subtilis (strain … protein
Buffer: 20 mM HEPES, 100 mM NaCl, 5 mM DTT, pH: 7.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2023 Feb 24
A general mechanism for initiating the bacterial general stress response. Elife 13 (2025)
Baral R, Ho K, Kumar RP, Hopkins JB, Watkins MB, LaRussa S, Caban-Penix S, Calderone LA, Bradshaw N
RgGuinier 3.9 nm
Dmax 14.3 nm
VolumePorod 117 nm3

SASDU95 – Hyperactive variant of phosphoserine phosphatase RsbU (Q94L) bound to the activator serine/threonine-protein kinase RsbT (heterotetrameric complex)

UniProt ID: P42411 (1-133) Serine/threonine-protein kinase RsbT

UniProt ID: P40399 (1-335) Phosphoserine phosphatase RsbU (Q94L)
Serine/threonine-protein kinase RsbTPhosphoserine phosphatase RsbU (Q94L) experimental SAS data
Serine/threonine-protein kinase RsbT Phosphoserine phosphatase RsbU (Q94L) Kratky plot
Sample: Serine/threonine-protein kinase RsbT dimer, 29 kDa Bacillus subtilis (strain … protein
Phosphoserine phosphatase RsbU (Q94L) dimer, 77 kDa Bacillus subtilis (strain … protein
Buffer: 20 mM HEPES, 100 mM NaCl, 5 mM DTT, pH: 7.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2023 Feb 24
A general mechanism for initiating the bacterial general stress response. Elife 13 (2025)
Baral R, Ho K, Kumar RP, Hopkins JB, Watkins MB, LaRussa S, Caban-Penix S, Calderone LA, Bradshaw N
RgGuinier 3.5 nm
Dmax 12.3 nm
VolumePorod 119 nm3

SASDUA5 – Double-stranded RNA-binding domains of Interleukin enhancer-binding factor 3 (395-592)

UniProt ID: Q9Z1X4 (395-592) Interleukin enhancer-binding factor 3
Interleukin enhancer-binding factor 3 experimental SAS data
GASBOR model
Sample: Interleukin enhancer-binding factor 3 monomer, 21 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2017 Oct 23
Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerization on binding dsRNA. Nucleic Acids Res 53(6) (2025)
Winterbourne S, Jayachandran U, Zou J, Rappsilber J, Granneman S, Cook AG
RgGuinier 3.5 nm
Dmax 12.6 nm
VolumePorod 39 nm3

SASDUB5 – Heterodimer complex of domain-associated zinc finger domains of Interleukin enhancer-binding factor 2 (29-390) and Interleukin enhancer-binding factor 3 (1-381)

UniProt ID: Q9Z1X4 (1-381) Interleukin enhancer-binding factor 3

UniProt ID: Q9CXY6 (29-390) Interleukin enhancer-binding factor 2
Interleukin enhancer-binding factor 3Interleukin enhancer-binding factor 2 experimental SAS data
GASBOR model
Sample: Interleukin enhancer-binding factor 3 monomer, 42 kDa Mus musculus protein
Interleukin enhancer-binding factor 2 monomer, 40 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2017 Oct 23
Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerization on binding dsRNA. Nucleic Acids Res 53(6) (2025)
Winterbourne S, Jayachandran U, Zou J, Rappsilber J, Granneman S, Cook AG
RgGuinier 3.5 nm
Dmax 12.6 nm
VolumePorod 127 nm3

SASDUC5 – Interleukin enhancer-binding factor 3 (1-591) and Interleukin enhancer-binding factor 2 (1-390) heterodimer complex (SEC-SAXS 1)

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3
Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 3 experimental SAS data
DAMMIN model
Sample: Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 May 9
Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerization on binding dsRNA. Nucleic Acids Res 53(6) (2025)
Winterbourne S, Jayachandran U, Zou J, Rappsilber J, Granneman S, Cook AG
RgGuinier 4.7 nm
Dmax 17.1 nm
VolumePorod 210 nm3

SASDUD5 – Interleukin enhancer-binding factor 3 (1-591) and Interleukin enhancer-binding factor 2 (1-390) heterodimer complex (SEC-SAXS 2)

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2
Interleukin enhancer-binding factor 3Interleukin enhancer-binding factor 2 experimental SAS data
GASBOR model
Sample: Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2017 Oct 23
Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerization on binding dsRNA. Nucleic Acids Res 53(6) (2025)
Winterbourne S, Jayachandran U, Zou J, Rappsilber J, Granneman S, Cook AG
RgGuinier 4.7 nm
Dmax 17.1 nm
VolumePorod 210 nm3

SASDUE5 – Interleukin enhancer-binding factor 3 (1-591) and Interleukin enhancer-binding factor 2 (1-390) heterodimer complex oligomerised along 25mer of dsRNA in a 2:1 ratio

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: None (None-None) 25-mer dsRNA

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3
Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 325-mer dsRNAInterleukin enhancer-binding factor 2Interleukin enhancer-binding factor 3 experimental SAS data
DAMMIN model
Sample: Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
25-mer dsRNA monomer, 16 kDa RNA
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 May 9
Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerization on binding dsRNA. Nucleic Acids Res 53(6) (2025)
Winterbourne S, Jayachandran U, Zou J, Rappsilber J, Granneman S, Cook AG
RgGuinier 5.7 nm
Dmax 19.9 nm
VolumePorod 453 nm3

SASDUF5 – Interleukin enhancer-binding factor 3 (1-591) and Interleukin enhancer-binding factor 2 (1-390) heterodimer complex oligomerised along 25mer of dsRNA in a 4:1 ratio

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: None (None-None) 25-mer dsRNA

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3
Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 325-mer dsRNAInterleukin enhancer-binding factor 2Interleukin enhancer-binding factor 3 experimental SAS data
DAMMIN model
Sample: Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
25-mer dsRNA monomer, 16 kDa RNA
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 May 9
Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerization on binding dsRNA. Nucleic Acids Res 53(6) (2025)
Winterbourne S, Jayachandran U, Zou J, Rappsilber J, Granneman S, Cook AG
RgGuinier 5.7 nm
Dmax 20.5 nm
VolumePorod 431 nm3

SASDUG5 – Interleukin enhancer-binding factor 3 (1-591) and Interleukin enhancer-binding factor 2 (1-390) heterodimer complex oligomerised along 36mer of dsRNA in a 2:1 ratio

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: None (None-None) 36-mer dsRNA

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3
Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 3Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 336-mer dsRNAInterleukin enhancer-binding factor 2Interleukin enhancer-binding factor 3 experimental SAS data
DAMMIN model
Sample: Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
36-mer dsRNA monomer, 23 kDa RNA
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 May 9
Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerization on binding dsRNA. Nucleic Acids Res 53(6) (2025)
Winterbourne S, Jayachandran U, Zou J, Rappsilber J, Granneman S, Cook AG
RgGuinier 6.1 nm
Dmax 21.2 nm
VolumePorod 587 nm3