SASBDB entries for UniProt ID:

SASDUH5 – Interleukin enhancer-binding factor 3 (1-591) and Interleukin enhancer-binding factor 2 (1-390) heterodimer complex oligomerised along 36mer of dsRNA in a 4:1 ratio

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: None (None-None) 36-mer dsRNA

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3
Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 3Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 336-mer dsRNAInterleukin enhancer-binding factor 2Interleukin enhancer-binding factor 3 experimental SAS data
DAMMIN model
Sample: Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
36-mer dsRNA monomer, 23 kDa RNA
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 May 9
Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerization on binding dsRNA. Nucleic Acids Res 53(6) (2025)
Winterbourne S, Jayachandran U, Zou J, Rappsilber J, Granneman S, Cook AG
RgGuinier 6.4 nm
Dmax 22.1 nm
VolumePorod 626 nm3

SASDUJ5 – Interleukin enhancer-binding factor 3 (1-591) and Interleukin enhancer-binding factor 2 (1-390) heterodimer complex oligomerised along 54mer of dsRNA in a 2:1 ratio

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: None (None-None) 54-mer dsRNA
Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 3Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 3Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 354-mer dsRNA experimental SAS data
DAMMIN model
Sample: Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
54-mer dsRNA monomer, 35 kDa RNA
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 May 9
Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerization on binding dsRNA. Nucleic Acids Res 53(6) (2025)
Winterbourne S, Jayachandran U, Zou J, Rappsilber J, Granneman S, Cook AG
RgGuinier 7.1 nm
Dmax 25.0 nm
VolumePorod 797 nm3

SASDUK5 – Interleukin enhancer-binding factor 3 (1-591) and Interleukin enhancer-binding factor 2 (1-390) heterodimer complex oligomerised along 54mer of dsRNA in a 4:1 ratio

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: None (None-None) 54-mer dsRNA

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2
Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 3Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 3Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 354-mer dsRNAInterleukin enhancer-binding factor 3Interleukin enhancer-binding factor 2 experimental SAS data
DAMMIN model
Sample: Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
54-mer dsRNA monomer, 35 kDa RNA
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 May 9
Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerization on binding dsRNA. Nucleic Acids Res 53(6) (2025)
Winterbourne S, Jayachandran U, Zou J, Rappsilber J, Granneman S, Cook AG
RgGuinier 7.7 nm
Dmax 26.5 nm
VolumePorod 1075 nm3

SASDUL5 – Interleukin enhancer-binding factor 3 (1-591) and Interleukin enhancer-binding factor 2 (1-390) heterodimer complex oligomerised along 54mer of dsRNA in a 6:1 ratio

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: None (None-None) 54-mer dsRNA

UniProt ID: Q9Z1X4 (2-591) Interleukin enhancer-binding factor 3

UniProt ID: Q12905 (1-390) Interleukin enhancer-binding factor 2
Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 3Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 3Interleukin enhancer-binding factor 2Interleukin enhancer-binding factor 354-mer dsRNAInterleukin enhancer-binding factor 3Interleukin enhancer-binding factor 2 experimental SAS data
DAMMIN model
Sample: Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
54-mer dsRNA monomer, 35 kDa RNA
Interleukin enhancer-binding factor 3 monomer, 66 kDa Mus musculus protein
Interleukin enhancer-binding factor 2 monomer, 44 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 May 9
Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerization on binding dsRNA. Nucleic Acids Res 53(6) (2025)
Winterbourne S, Jayachandran U, Zou J, Rappsilber J, Granneman S, Cook AG
RgGuinier 7.8 nm
Dmax 26.1 nm
VolumePorod 1050 nm3

SASDUM5 – Mycobacterium smegmatis Inosine-5'-monophosphate dehydrogenase (IMPDH) - apo form

UniProt ID: A0QSU3 (2-513) Inosine-5'-monophosphate dehydrogenase
Inosine-5'-monophosphate dehydrogenase experimental SAS data
PYMOL model
Sample: Inosine-5'-monophosphate dehydrogenase octamer, 426 kDa Mycolicibacterium smegmatis (strain … protein
Buffer: 50 mM HEPES, 200 mM KCl, 2 mM MgCl2, 0.5 mM TCEP, pH: 7.5
Experiment: SAXS data collected at Anton Paar SAXSpoint 2.0, Institute of Biotechnology, Czech Academy of Sciences/Centre of Molecular Structure on 2024 Feb 21
Deciphering the allosteric regulation of mycobacterial inosine-5′-monophosphate dehydrogenase Nature Communications 15(1) (2024)
Bulvas O, Knejzlík Z, Sýs J, Filimoněnko A, Čížková M, Clarová K, Rejman D, Kouba T, Pichová I
RgGuinier 5.3 nm
Dmax 24.5 nm
VolumePorod 952 nm3

SASDUN5 – Mycobacterium smegmatis Inosine-5'-monophosphate dehydrogenase (IMPDH) - IMP-bound form

UniProt ID: A0QSU3 (2-513) Inosine-5'-monophosphate dehydrogenase
Inosine-5'-monophosphate dehydrogenase experimental SAS data
PYMOL model
Sample: Inosine-5'-monophosphate dehydrogenase tetramer, 213 kDa Mycolicibacterium smegmatis (strain … protein
Buffer: 50 mM HEPES, 200 mM KCl, 2 mM MgCl2, 0.5 mM TCEP, pH: 7.5
Experiment: SAXS data collected at Anton Paar SAXSpoint 2.0, Institute of Biotechnology, Czech Academy of Sciences/Centre of Molecular Structure on 2024 Mar 6
Deciphering the allosteric regulation of mycobacterial inosine-5′-monophosphate dehydrogenase Nature Communications 15(1) (2024)
Bulvas O, Knejzlík Z, Sýs J, Filimoněnko A, Čížková M, Clarová K, Rejman D, Kouba T, Pichová I
RgGuinier 5.0 nm
Dmax 21.5 nm
VolumePorod 471 nm3

SASDUP5 – Mycobacterium smegmatis Inosine-5'-monophosphate dehydrogenase (IMPDH) - ATP-bound form

UniProt ID: A0QSU3 (2-513) Inosine-5'-monophosphate dehydrogenase
Inosine-5'-monophosphate dehydrogenase experimental SAS data
PYMOL model
Sample: Inosine-5'-monophosphate dehydrogenase octamer, 426 kDa Mycolicibacterium smegmatis (strain … protein
Buffer: 50 mM HEPES, 200 mM KCl, 2 mM MgCl2, 0.5 mM TCEP, pH: 7.5
Experiment: SAXS data collected at Anton Paar SAXSpoint 2.0, Institute of Biotechnology, Czech Academy of Sciences/Centre of Molecular Structure on 2024 Jan 29
Deciphering the allosteric regulation of mycobacterial inosine-5′-monophosphate dehydrogenase Nature Communications 15(1) (2024)
Bulvas O, Knejzlík Z, Sýs J, Filimoněnko A, Čížková M, Clarová K, Rejman D, Kouba T, Pichová I
RgGuinier 5.0 nm
Dmax 14.8 nm
VolumePorod 821 nm3

SASDUQ5 – Mycobacterium smegmatis Inosine-5'-monophosphate dehydrogenase (IMPDH) - ATP+IMP-bound form

UniProt ID: A0QSU3 (2-513) Inosine-5'-monophosphate dehydrogenase
Inosine-5'-monophosphate dehydrogenase experimental SAS data
PYMOL model
Sample: Inosine-5'-monophosphate dehydrogenase octamer, 426 kDa Mycolicibacterium smegmatis (strain … protein
Buffer: 50 mM HEPES, 200 mM KCl, 2 mM MgCl2, 0.5 mM TCEP, pH: 7.5
Experiment: SAXS data collected at Anton Paar SAXSpoint 2.0, Institute of Biotechnology, Czech Academy of Sciences/Centre of Molecular Structure on 2024 Mar 6
Deciphering the allosteric regulation of mycobacterial inosine-5′-monophosphate dehydrogenase Nature Communications 15(1) (2024)
Bulvas O, Knejzlík Z, Sýs J, Filimoněnko A, Čížková M, Clarová K, Rejman D, Kouba T, Pichová I
RgGuinier 5.1 nm
Dmax 13.2 nm
VolumePorod 784 nm3

SASDUR5 – Mycobacterium smegmatis Inosine-5'-monophosphate dehydrogenase (IMPDH) - GTP-bound form

UniProt ID: A0QSU3 (2-513) Inosine-5'-monophosphate dehydrogenase
Inosine-5'-monophosphate dehydrogenase experimental SAS data
PYMOL model
Sample: Inosine-5'-monophosphate dehydrogenase octamer, 426 kDa Mycolicibacterium smegmatis (strain … protein
Buffer: 50 mM HEPES, 200 mM KCl, 2 mM MgCl2, 0.5 mM TCEP, pH: 7.5
Experiment: SAXS data collected at Anton Paar SAXSpoint 2.0, Institute of Biotechnology, Czech Academy of Sciences/Centre of Molecular Structure on 2024 Mar 6
Deciphering the allosteric regulation of mycobacterial inosine-5′-monophosphate dehydrogenase Nature Communications 15(1) (2024)
Bulvas O, Knejzlík Z, Sýs J, Filimoněnko A, Čížková M, Clarová K, Rejman D, Kouba T, Pichová I
RgGuinier 5.0 nm
Dmax 14.4 nm
VolumePorod 810 nm3

SASDUS6 – Amino-terminal domain of Infectious Bursal Disease Virus VP3 at pH8.0

UniProt ID: P61825 (756-836) Structural polyprotein
Structural polyprotein experimental SAS data
Structural polyprotein Kratky plot
Sample: Structural polyprotein dimer, 26 kDa Infectious bursal disease … protein
Buffer: 50 mM Tris, 500 mM NaCl, 2 mM DTT, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2017 Sep 27
Infectious Bursal Disease Virus VP3
Diego Ferrero
RgGuinier 2.4 nm
Dmax 10.0 nm
VolumePorod 52 nm3