SASBDB entries for UniProt ID:

SASDUG4 – Insulin-like growth factor 2 mRNA-binding protein 2 (IMP2), dimer with RNA

UniProt ID: Q9Y6M1 (1-599) Insulin-like growth factor 2 mRNA-binding protein 2

UniProt ID: None (None-None) Cox7B RNA
Insulin-like growth factor 2 mRNA-binding protein 2Cox7B RNA experimental SAS data
CHIMERA model
Sample: Insulin-like growth factor 2 mRNA-binding protein 2 dimer, 132 kDa Homo sapiens protein
Cox7B RNA monomer, 22 kDa RNA
Buffer: 20 mM HEPES, 2 mM MgCl2, 1 M NaCl, 10% glycerol v/v, 2 mM β-mercaptoethanol, pH: 7.4
Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2023 Nov 16
Structural insights into IMP2 dimerization and RNA binding
Raktim Roy
RgGuinier 3.8 nm
Dmax 14.0 nm
VolumePorod 56 nm3

SASDUK4 – S9C peptidase from Geobacillus stearothermophilus

UniProt ID: A0A150M835 (17-670) Acylamino-acid-releasing enzyme (I277L, V491A)
Acylamino-acid-releasing enzyme (I277L, V491A) experimental SAS data
GASBOR model
Sample: Acylamino-acid-releasing enzyme (I277L, V491A) tetramer, 308 kDa Geobacillus stearothermophilus protein
Buffer: 10 mM Tris, 100 mM NaCl, pH: 8
Experiment: SAXS data collected at BL-18, INDUS-2 on 2023 Aug 11
Structural and functional analysis of S9C peptidases of Geobacillus stearothermophilus
Dr. Rahul Singh
RgGuinier 5.4 nm
Dmax 13.0 nm
VolumePorod 424 nm3

SASDUL4 – Signal transducer and activator of transcription 1-alpha/beta (STAT1)

UniProt ID: P42224 (1-750) Signal transducer and activator of transcription 1-alpha/beta
Signal transducer and activator of transcription 1-alpha/beta experimental SAS data
Signal transducer and activator of transcription 1-alpha/beta Kratky plot
Sample: Signal transducer and activator of transcription 1-alpha/beta tetramer, 349 kDa Homo sapiens protein
Buffer: 10 mM HEPES-NaOH, 150 mM NaCl, 3% glycerol, 2 mM DTT, pH: 7.4
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2022 Dec 11
Structural analysis reveals how tetrameric tyrosine-phosphorylated STAT1 is targeted by the rabies virus P-protein Science Signaling 18(878) (2025)
Sugiyama A, Minami M, Ugajin K, Inaba-Inoue S, Yabuno N, Takekawa Y, Xiaomei S, Takei S, Sasaki M, Nomai T, Jiang X, Kita S, Maenaka K, Hirose M, Yao M, Gooley P, Moseley G, Sugita Y, Ose T
RgGuinier 6.2 nm
Dmax 21.2 nm
VolumePorod 800 nm3

SASDUM4 – Signal transducer and activator of transcription 1-alpha/beta bound to phosphoprotein (STAT1/RVP)

UniProt ID: P42224 (1-750) Signal transducer and activator of transcription 1-alpha/beta

UniProt ID: Q9IPJ8 (1-297) Phosphoprotein
Signal transducer and activator of transcription 1-alpha/betaPhosphoprotein experimental SAS data
Signal transducer and activator of transcription 1-alpha/beta Phosphoprotein Kratky plot
Sample: Signal transducer and activator of transcription 1-alpha/beta tetramer, 349 kDa Homo sapiens protein
Phosphoprotein monomer, 33 kDa Rabies virus (strain … protein
Buffer: 10 mM HEPES-NaOH, 150 mM NaCl, 3% glycerol, 2 mM DTT, pH: 7.4
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2022 Dec 11
Structural analysis reveals how tetrameric tyrosine-phosphorylated STAT1 is targeted by the rabies virus P-protein Science Signaling 18(878) (2025)
Sugiyama A, Minami M, Ugajin K, Inaba-Inoue S, Yabuno N, Takekawa Y, Xiaomei S, Takei S, Sasaki M, Nomai T, Jiang X, Kita S, Maenaka K, Hirose M, Yao M, Gooley P, Moseley G, Sugita Y, Ose T
RgGuinier 6.5 nm
Dmax 26.0 nm
VolumePorod 857 nm3

SASDUN4 – Signal transducer and activator of transcription 1-alpha/beta bound to transducer/activator DNA (STAT1/DNA)

UniProt ID: P42224 (1-750) Signal transducer and activator of transcription 1-alpha/beta

UniProt ID: None (None-None) Signal transducer and activator of transcription 1 binding DNA
Signal transducer and activator of transcription 1-alpha/betaSignal transducer and activator of transcription 1 binding DNA experimental SAS data
Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 1 binding DNA Kratky plot
Sample: Signal transducer and activator of transcription 1-alpha/beta tetramer, 349 kDa Homo sapiens protein
Signal transducer and activator of transcription 1 binding DNA dimer, 11 kDa Homo sapiens DNA
Buffer: 10 mM HEPES-NaOH, 150 mM NaCl, 3% glycerol, 2 mM DTT, pH: 7.4
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2022 Dec 11
Structural analysis reveals how tetrameric tyrosine-phosphorylated STAT1 is targeted by the rabies virus P-protein Science Signaling 18(878) (2025)
Sugiyama A, Minami M, Ugajin K, Inaba-Inoue S, Yabuno N, Takekawa Y, Xiaomei S, Takei S, Sasaki M, Nomai T, Jiang X, Kita S, Maenaka K, Hirose M, Yao M, Gooley P, Moseley G, Sugita Y, Ose T
RgGuinier 6.1 nm
Dmax 19.4 nm
VolumePorod 761 nm3

SASDUP4 – Dimer of the N-terminal 50 residues of the H-NS family protein MvaT

UniProt ID: Q88GF9 (1-50) H-NS family protein MvaT
H-NS family protein MvaT experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: H-NS family protein MvaT dimer, 12 kDa Pseudomonas putida (strain … protein
Buffer: 20 mM Tris-HCl, 500 mM NaCl, 10% glycerol, 500 mM Imidazole, pH: 8
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2019 May 24
Structural characterization of the native oligomerization mode of MvaT proteins in Pseudomonas. Microbiol Spectr :e0023526 (2026)
Vasileva D, Suzuki-Minakuchi C, Arakawa T, Moriwaki Y, Yonezawa K, Shimizu N, Fujimoto Z, Terada T, Okada K, Nojiri H
RgGuinier 2.9 nm
Dmax 14.0 nm

SASDUQ4 – Calcium/calmodulin-dependent protein kinase type II alpha (CaMKIIα) WT hub domain

UniProt ID: Q9UQM7 (345-475) Calcium/calmodulin-dependent protein kinase type II subunit alpha
Calcium/calmodulin-dependent protein kinase type II subunit alpha experimental SAS data
PYMOL model
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha dodecamer, 186 kDa Homo sapiens protein
Buffer: 20 mM MES, 150 mM NaCl, 1 mM DTT, pH: 6
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Oct 3
Ligand‐induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity Protein Science 33(10) (2024)
Narayanan D, Larsen A, Gauger S, Adafia R, Hammershøi R, Hamborg L, Bruus‐Jensen J, Griem‐Krey N, Gee C, Frølund B, Stratton M, Kuriyan J, Kastrup J, Langkilde A, Wellendorph P, Solbak S
RgGuinier 4.5 nm
Dmax 15.2 nm
VolumePorod 367 nm3

SASDUR4 – Calcium/calmodulin-dependent protein kinase type II alpha (CaMKIIα) WT hub domain

UniProt ID: Q9UQM7 (345-475) Calcium/calmodulin-dependent protein kinase type II subunit alpha
Calcium/calmodulin-dependent protein kinase type II subunit alpha experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha dodecamer, 186 kDa Homo sapiens protein
Buffer: 20 mM MES, 150 mM NaCl, 1 mM DTT, pH: 6
Experiment: SAXS data collected at Xenocs BioXolver L with MetalJet, University of Copenhagen, Department of Drug Design and Pharmacology on 2020 Nov 19
Ligand‐induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity Protein Science 33(10) (2024)
Narayanan D, Larsen A, Gauger S, Adafia R, Hammershøi R, Hamborg L, Bruus‐Jensen J, Griem‐Krey N, Gee C, Frølund B, Stratton M, Kuriyan J, Kastrup J, Langkilde A, Wellendorph P, Solbak S
RgGuinier 4.4 nm
Dmax 14.9 nm
VolumePorod 351 nm3

SASDUS4 – Calcium/calmodulin-dependent protein kinase type II alpha (CaMKIIα) WT hub domain with PIPA (i)

UniProt ID: Q9UQM7 (345-475) Calcium/calmodulin-dependent protein kinase type II subunit alpha

UniProt ID: None (None-None) 2-(6-(4-chlorophenyl)imidazo[1,2-b]pyridazine-2-yl)acetic acid
Calcium/calmodulin-dependent protein kinase type II subunit alpha2-(6-(4-chlorophenyl)imidazo[1,2-b]pyridazine-2-yl)acetic acid experimental SAS data
PYMOL model
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha dodecamer, 186 kDa Homo sapiens protein
2-(6-(4-chlorophenyl)imidazo[1,2-b]pyridazine-2-yl)acetic acid monomer, 0 kDa
Buffer: 20 mM MES, 150 mM NaCl, 1 mM DTT, 200 µM PIPA, pH: 6
Experiment: SAXS data collected at Xenocs BioXolver L with MetalJet, University of Copenhagen, Department of Drug Design and Pharmacology on 2022 Nov 30
Ligand‐induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity Protein Science 33(10) (2024)
Narayanan D, Larsen A, Gauger S, Adafia R, Hammershøi R, Hamborg L, Bruus‐Jensen J, Griem‐Krey N, Gee C, Frølund B, Stratton M, Kuriyan J, Kastrup J, Langkilde A, Wellendorph P, Solbak S
RgGuinier 4.8 nm
Dmax 16.0 nm
VolumePorod 396 nm3

SASDUT4 – Calcium/calmodulin-dependent protein kinase type II alpha (CaMKIIα) WT hub domain with PIPA (ii)

UniProt ID: Q9UQM7 (345-475) Calcium/calmodulin-dependent protein kinase type II subunit alpha

UniProt ID: None (None-None) 2-(6-(4-chlorophenyl)imidazo[1,2-b]pyridazine-2-yl)acetic acid
Calcium/calmodulin-dependent protein kinase type II subunit alpha2-(6-(4-chlorophenyl)imidazo[1,2-b]pyridazine-2-yl)acetic acid experimental SAS data
PYMOL model
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha dodecamer, 186 kDa Homo sapiens protein
2-(6-(4-chlorophenyl)imidazo[1,2-b]pyridazine-2-yl)acetic acid monomer, 0 kDa
Buffer: 20 mM MES, 150 mM NaCl, 1 mM DTT, 200 µM PIPA, pH: 6
Experiment: SAXS data collected at Xenocs BioXolver L with MetalJet, University of Copenhagen, Department of Drug Design and Pharmacology on 2023 May 30
Ligand‐induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity Protein Science 33(10) (2024)
Narayanan D, Larsen A, Gauger S, Adafia R, Hammershøi R, Hamborg L, Bruus‐Jensen J, Griem‐Krey N, Gee C, Frølund B, Stratton M, Kuriyan J, Kastrup J, Langkilde A, Wellendorph P, Solbak S
RgGuinier 5.5 nm
Dmax 27.0 nm