SASBDB entries for UniProt ID:

SASDXJ4 – Allergen Hev b 8 protein, Profilin-2

UniProt ID: Q9STB6 (1-131) Profilin-2
Profilin-2 experimental SAS data
GASBOR model
Sample: Profilin-2 monomer, 18 kDa Hevea brasiliensis protein
Buffer: 20 mM Tris, 50 mM NaCl, pH: 8.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2025 Apr 11
Allergen-induced structural rearrangements in IgE: insights from SAXS and molecular dynamics. Int J Biol Macromol :147658 (2025)
Gómez-Velasco H, García-Ramírez B, Siliqi D, Graewert MA, Quintero-Martinez A, Ortega E, Rodríguez-Romero A
RgGuinier 1.7 nm
Dmax 4.5 nm
VolumePorod 21 nm3

SASDB66 – Deglycosylated myelin-associated glycoprotein full extracellular domain (Ig 1-5) N406Q mutant

UniProt ID: P20917 (20-508) Myelin-associated glycoprotein (20-508; N406Q mutant)
Myelin-associated glycoprotein (20-508; N406Q mutant) experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Myelin-associated glycoprotein (20-508; N406Q mutant) monomer, 54 kDa Mus musculus protein
Buffer: 20 mM HEPES 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2015 Jul 28
Structural basis of myelin-associated glycoprotein adhesion and signalling. Nat Commun 7:13584 (2016)
Pronker MF, Lemstra S, Snijder J, Heck AJ, Thies-Weesie DM, Pasterkamp RJ, Janssen BJ
RgGuinier 7.8 nm
Dmax 29.0 nm
VolumePorod 216 nm3

SASDCP4 – Collagenase ColH s2as2bs3 at pCa 4

UniProt ID: Q46085 (718-1021) Collagenase ColH segement s2as2bs3
Collagenase ColH segement s2as2bs3 experimental SAS data
DAMMIF model
Sample: Collagenase ColH segement s2as2bs3 monomer, 34 kDa Hathewaya histolytica protein
Buffer: 10mM HEPES 100mM NaCl 0.2mM EGTA, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2016 Oct 12
Ca2+ - Induced Structural Change of Multi-Domain Collagen Binding Segments of Collagenases ColG and ColH from Hathewaya histolytica University of Arkansas Dissertation - (2018)
Christopher E Ruth
RgGuinier 3.2 nm
Dmax 13.1 nm
VolumePorod 37 nm3

SASDD88 – The BRCT domain from Mycobacterium tuberculosis DNA ligase

UniProt ID: P9WNV1 (601-691) M.tb. LigA BRCT domain (DNA ligase A)
M.tb. LigA BRCT domain (DNA ligase A) experimental SAS data
DAMMIN model
Sample: M.tb. LigA BRCT domain (DNA ligase A) monomer, 13 kDa Mycobacterium tuberculosis protein
Buffer: 50 mM Tris-HCl 500 mM NaCl 5mM β-mercaptoethanol, pH: 8
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2018 Jun 2
M. tuberculosis class II apurinic/ apyrimidinic-endonuclease/3'-5' exonuclease (XthA) engages with NAD+-dependent DNA ligase A (LigA) to counter futile cleavage and ligation cycles in base excision repair. Nucleic Acids Res (2020)
Khanam T, Afsar M, Shukla A, Alam F, Kumar S, Soyar H, Dolma K, Pasupuleti M, Srivastava KK, Ampapathi RS, Ramachandran R
RgGuinier 1.6 nm
Dmax 3.7 nm
VolumePorod 23 nm3

SASDEU3 – GST-SAUL1

UniProt ID: Q9LM76 (None-None) Senescence-associated E3 ubiquitin ligase 1

UniProt ID: P08515 (None-None) Glutathione S-transferase
Senescence-associated E3 ubiquitin ligase 1Glutathione S-transferase experimental SAS data
CORAL model
Sample: Senescence-associated E3 ubiquitin ligase 1 tetramer, 355 kDa Arabidopsis thaliana protein
Glutathione S-transferase tetramer, 106 kDa Schistosoma japonicum protein
Buffer: 50 mM Tris, 250 mM NaCl, pH: 9
Experiment: SAXS data collected at EMBL P12, PETRA III on 2014 Jan 20
Senescence-associated ubiquitin ligase 1 (SAUL1)
Haifa El Kilani, Al Kikhney
RgGuinier 7.6 nm
Dmax 28.0 nm
VolumePorod 778 nm3

SASDE49 – Interleukin-1 receptor accessory protein ectodomains with ST2 linker

UniProt ID: Q9NPH3 (21-348) Interleukin-1 receptor accessory protein ectodomains with ST2 linker
Interleukin-1 receptor accessory protein ectodomains with ST2 linker experimental SAS data
BILBOMD model
Sample: Interleukin-1 receptor accessory protein ectodomains with ST2 linker monomer, 41 kDa Homo sapiens protein
Buffer: 10mM HEPES, 150mM NaCl, 3% glycerol, pH: 7.2
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Jul 24
Functional Relevance of Interleukin-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling. Structure 27(8):1296-1307.e5 (2019)
Ge J, Remesh SG, Hammel M, Pan S, Mahan AD, Wang S, Wang X
RgGuinier 3.1 nm
Dmax 10.7 nm
VolumePorod 76 nm3

SASDF36 – DNA-binding protein HU-alpha bound to 80 base-pair DNA at pH 4.5 with 50 mM NaCl

UniProt ID: None (None-None) 80bp_DNA Forward

UniProt ID: None (None-None) 80bp_DNA Reverse

UniProt ID: P0ACF0 (1-90) DNA-binding protein HU-alpha
80bp_DNA Forward80bp_DNA ReverseDNA-binding protein HU-alpha experimental SAS data
80bp_DNA Forward 80bp_DNA Reverse DNA-binding protein HU-alpha Kratky plot
Sample: 80bp_DNA Forward monomer, 25 kDa Escherichia coli DNA
80bp_DNA Reverse monomer, 25 kDa Escherichia coli DNA
DNA-binding protein HU-alpha, 10 kDa Escherichia coli protein
Buffer: 10 mM sodium acetate, 50 mM NaCl, pH: 4.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2018 May 27
Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling. Nat Commun 11(1):2905 (2020)
Remesh SG, Verma SC, Chen JH, Ekman AA, Larabell CA, Adhya S, Hammel M

SASDG84 – Autoinhibited dimer of truncated 6xHis Cytohesin-2 (ARNO, amino acids 2-400) with Inositol 1,3,4,5-tetrakis phosphate (DAMMIF, GASBOR and antiparallel CORAL models)

UniProt ID: P63034 (2-400) Cytohesin-2
Cytohesin-2 experimental SAS data
DAMMIF model
Sample: Cytohesin-2 dimer, 95 kDa Mus musculus protein
Buffer: 20 mM Tris, 150 mM NaCl, 2 mM MgCl2, 0.1% 2-mercaptoethanol, 5% glycerol, 0.001 mM insitol 1,3,4,5-tetrakis phosphate, pH: 8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2013 Nov 15
Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes. Structure (2019)
Das S, Malaby AW, Nawrotek A, Zhang W, Zeghouf M, Maslen S, Skehel M, Chakravarthy S, Irving TC, Bilsel O, Cherfils J, Lambright DG
RgGuinier 5.3 nm
Dmax 27.0 nm
VolumePorod 180 nm3

SASDJ25 – DNA-dependent protein kinase/ X-ray repair cross-complementing protein 5 and 6 complex bound to DNA (DNA-PK monomer/dimer)

UniProt ID: P12956 (1-609) X-ray repair cross-complementing protein 6

UniProt ID: P13010 (1-732) X-ray repair cross-complementing protein 5

UniProt ID: P78527 (10-4128) DNA-dependent protein kinase catalytic subunit

UniProt ID: None (None-None) dsDNA
X-ray repair cross-complementing protein 6X-ray repair cross-complementing protein 5DNA-dependent protein kinase catalytic subunitdsDNA experimental SAS data
BILBOMD model
Sample: X-ray repair cross-complementing protein 6 monomer, 70 kDa Homo sapiens protein
X-ray repair cross-complementing protein 5 monomer, 83 kDa Homo sapiens protein
DNA-dependent protein kinase catalytic subunit monomer, 468 kDa Homo sapiens protein
DsDNA dimer, 21 kDa DNA
Buffer: 50 mM Tris-HCl, 100 mM NaCl, 5% glycerol, 0.01% sodium azide, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2016 Dec 30
Visualizing functional dynamicity in the DNA-dependent protein kinase holoenzyme DNA-PK complex by integrating SAXS with cryo-EM. Prog Biophys Mol Biol (2020)
Hammel M, Rosenberg DJ, Bierma J, Hura GL, Lees-Miller SP, Tainer JA
RgGuinier 7.5 nm
Dmax 29.4 nm
VolumePorod 1440 nm3

SASDJX9 – Mammalian cell entry protein 4A (Mce4A121-400)

UniProt ID: None (None-None) n-Dodecyl-β-D-Maltopyranoside

UniProt ID: I6YC99 (121-400) Mce-family protein Mce4A
n-Dodecyl-β-D-MaltopyranosideMce-family protein Mce4A experimental SAS data
CUSTOM IN-HOUSE model
Sample: N-Dodecyl-β-D-Maltopyranoside 0, 102 kDa
Mce-family protein Mce4A monomer, 35 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 50mM Tris, 500mM NaCl, 10% Glycerol, 5mM DDM, 1mM Beta-ME, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Nov 28
Structural insights into the substrate-binding proteins Mce1A and Mce4A from Mycobacterium tuberculosis IUCrJ 8(5) (2021)
Asthana P, Singh D, Pedersen J, Hynönen M, Sulu R, Murthy A, Laitaoja M, Jänis J, Riley L, Venkatesan R
RgGuinier 5.0 nm
Dmax 19.1 nm
VolumePorod 278 nm3