SASBDB entries for UniProt ID: Q9WTL8

SASDF27 – Brain and Muscle ARNT-Like 1 from Mus musculus (D530-L625), monomer, trans-conformation locking mutation P624A

UniProt ID: Q9WTL8-2 (530-625) Aryl hydrocarbon receptor nuclear translocator-like protein 1

Aryl hydrocarbon receptor nuclear translocator-like protein 1 experimental SAS data
DAMMIN model
Sample: Aryl hydrocarbon receptor nuclear translocator-like protein 1 monomer, 10 kDa Mus musculus protein
Buffer: 25 mM Hepes, 150 NaCl, 1 mM DTT, 5% Glycerol, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 27
Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein. J Biol Chem (2019)
Garg A, Orru R, Ye W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
RgGuinier 2.8 nm
Dmax 11.0 nm

SASDF47 – Complex of CBP KIX domain with BMAL1 (D530-L625) including C-terminal transactivation domain (TAD) (Mus musculus)

UniProt ID: Q9WTL8-2 (530-625) Aryl hydrocarbon receptor nuclear translocator-like protein 1

UniProt ID: P45481 (586-672) Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP), mutation L664C

Aryl hydrocarbon receptor nuclear translocator-like protein 1Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP), mutation L664C experimental SAS data
DAMMIN model
Sample: Aryl hydrocarbon receptor nuclear translocator-like protein 1 monomer, 10 kDa Mus musculus protein
Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP), mutation L664C monomer, 10 kDa Mus musculus protein
Buffer: 25 mM Hepes, 150 NaCl, 1 mM DTT, 5% Glycerol, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 27
Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein. J Biol Chem (2019)
Garg A, Orru R, Ye W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
RgGuinier 2.8 nm
Dmax 11.5 nm

SASDF57 – Complex of CBP KIX domain with BMAL1 (G517-L625) including C-terminal transactivation domain (TAD) (Mus musculus)

UniProt ID: Q9WTL8-2 (517-625) Brain and muscle ARNT-like 1 (G517-L625) including transactivation domain (TAD)

UniProt ID: P45481 (586-672) Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP)

Brain and muscle ARNT-like 1 (G517-L625) including transactivation domain (TAD)Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP) experimental SAS data
DAMMIN model
Sample: Brain and muscle ARNT-like 1 (G517-L625) including transactivation domain (TAD) monomer, 11 kDa Mus musculus protein
Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP) monomer, 10 kDa Mus musculus protein
Buffer: 25 mM Hepes, 150 NaCl, 1 mM DTT, 5% Glycerol, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 27
Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein. J Biol Chem (2019)
Garg A, Orru R, Ye W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
RgGuinier 3.1 nm
Dmax 13.7 nm

SASDF67 – Complex of CBP KIX domain with BMAL1 (G490-L625) including C-terminal transactivation domain (TAD) (Mus musculus)

UniProt ID: P45481 (586-672) Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP)

UniProt ID: Q9WTL8-2 (490-625) Brain and muscle ARNT-like 1 (G490-L625) including transactivation domain (TAD)

Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP)Brain and muscle ARNT-like 1 (G490-L625) including transactivation domain (TAD) experimental SAS data
DAMMIN model
Sample: Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP) monomer, 10 kDa Mus musculus protein
Brain and muscle ARNT-like 1 (G490-L625) including transactivation domain (TAD) monomer, 14 kDa Mus musculus protein
Buffer: 25 mM Hepes, 150 NaCl, 1 mM DTT, 5% Glycerol, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 27
Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein. J Biol Chem (2019)
Garg A, Orru R, Ye W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
RgGuinier 3.8 nm
Dmax 17.5 nm