Curated repository for small angle scattering data and models


SASBDB currently contains:


4886

experimental data sets

6065

models
547 experimental data sets on hold
785 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDU89 – Apolipoprotein A-I monomer, C-terminally truncated

Apolipoprotein A-I experimental SAS data
COOT model
Sample: Apolipoprotein A-I monomer, 22 kDa Homo sapiens protein
Buffer: 20 mM Tris, 150 mM NaCl, 0.1% sodium azide, pH: 7.4
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2021 Mar 20
The structure of the apolipoprotein A-I monomer provides insights into its oligomerisation and lipid-binding mechanisms Journal of Molecular Biology :169394 (2025)
Tou H, Rosenes Z, Khandokar Y, Zlatic C, Metcalfe R, Mok Y, Morton C, Gooley P, Griffin M
RgGuinier 2.3 nm
Dmax 7.9 nm
VolumePorod 27 nm3

UvrB (UvrABC system protein B)
UvrABC system protein B experimental SAS data
Inhibition of Mycobacterium tuberculosis UvrB by small molecules: Potent NER disruption and structural insights into dimer conformation. Int J Biol Macromol 2025 Sep 3;:147338
Int J Biol Macromol :147338 (2025 Sep 3)
Peroxisomal targeting signal receptor Pex5 from P. pastoris
Peroxisomal targeting signal receptor experimental SAS data
Structure of Pex8 in complex with peroxisomal receptor Pex5 reveals its essential role in peroxisomal cargo translocation 2025 Sep 02
(2025 Sep 02)
Transthyretin tetramer with over-saturated tolcapone
TransthyretinTolcapone experimental SAS data
Differentiating the solution structures and stability of transthyretin tetramer complexed with tolcapone and tafamidis using SEC-SWAXS and NMR. J Appl Crystallogr 2025 Aug 1;58(Pt 4):1373-1383
J Appl Crystallogr 58(Pt 4):1373-1383 (2025 Aug 1)
ST9a RNA, PKmutant (59 nucleotides in 0 mM MgCl2; monomer)
ST9 PKmutant (59 nt RNA) experimental SAS data
A conserved viral RNA fold enables nuclease resistance across kingdoms of life. Nucleic Acids Res 2025 Aug 27;53(16)
Nucleic Acids Res 53(16) (2025 Aug 27)
Thomasclavelia ramosa immunoglobulin A protease middle (protease) domain
IgA protease experimental SAS data
Structure of the Thomasclavelia ramosa immunoglobulin A protease reveals a modular and minimizable architecture distinct from other immunoglobulin A proteases. Proc Natl Acad Sci U S A 2025 Sep 2;122(35):e2503549122
Proc Natl Acad Sci U S A 122(35):e2503549122 (2025 Sep 2)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.