Curated repository for small angle scattering data and models


SASBDB currently contains:


5457

experimental data sets

6627

models
572 experimental data sets on hold
877 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDYM2 – Human prothrombin complex with the oligonucleotide aptamer NU172

Human prothrombinNU172 experimental SAS data
MULTIFOXS model
Sample: Human prothrombin monomer, 72 kDa Homo sapiens protein
NU172 monomer, 8 kDa DNA
Buffer: 10 mM Tris-HCl, 137 mM NaCl, 2.7 mM KCl, 5 mM CaCl2, 1% v/v glycerol,, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Apr 29
Prothrombin recognition and conformational modulation by anti-thrombin anticoagulant aptamers. Mol Ther (2026)
Troisi R, Cangiano A, Cowieson N, Spiridonova V, Pozzi N, Del Vecchio P, Paduano L, Sica F
RgGuinier 3.9 nm
Dmax 13.8 nm
VolumePorod 124 nm3

Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein DH/PH domain and DEP1 module (P-Rex2 DH/PH-DEP1)
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 DH/PH-DEP1 experimental SAS data
The Rho guanine-nucleotide exchange factor P-Rex2 exhibits structural and regulatory features distinct from the related RhoGEF P-Rex1 Journal of Biological Chemistry 2026 Jul 302(7):113229
Journal of Biological Chemistry 302(7):113229 (2026 Jul)
Tumbleweed protein composed of synthetic constructs TW1 and TW2 linked covalently via SpyTag/SpyCatcher
Tumbleweed experimental SAS data
Clocked stepping of an artificial protein walker along a DNA track. Nat Nanotechnol 2026 Jul 6;
Nat Nanotechnol (2026 Jul 6)
Deglycosylated Fc gamma receptor IIb (CD32b) extracellular domain in complex with human IgG1 6G08 F(ab')
Low affinity immunoglobulin gamma Fc region receptor II-bHuman IgG1 F(ab') 6G08 experimental SAS data
Antibody binding geometry and affinity control inhibitory hFcγRIIB receptor signaling. Immunity 2026 Jun 25;
Immunity (2026 Jun 25)
Chitooligosaccharide deacetylase (NodB) from the marine bacterium Vibrio campbellii (VhCOD) native form
Chito oligosaccharide deacetylase from Vibrio harveyi experimental SAS data
The oligomeric state of chitooligosaccharide deacetylase from the marine bacterium Vibrio campbellii. Biophys Rep (N Y) 2026 Jun 24;:100275
Biophys Rep (N Y) :100275 (2026 Jun 24)
hexamer of human citrate synthase and human malate dehydrogenase 2
citrate synthaseMalate dehydrogenase, mitochondrialMalate dehydrogenase, mitochondrial experimental SAS data
Molecular architecture of the human citrate synthase–malate dehydrogenase 2 metabolon Acta Crystallographica Section D Structural Biology 2026 Jun 21 82(7):740-750
Acta Crystallographica Section D Structural Biology 82(7):740-750 (2026 Jun 21)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.