Curated repository for small angle scattering data and models


SASBDB currently contains:


4943

experimental data sets

6150

models
537 experimental data sets on hold
730 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDXY8 – Repeats-in-toxin domain Block V of Bifunctional hemolysin/adenylate cyclase, 10 mM SrCl2

Repeats-in-toxin domain Block V of adenylate cyclase toxin experimental SAS data
ALPHAFOLD model
Sample: Repeats-in-toxin domain Block V of adenylate cyclase toxin monomer, 19 kDa Bordetella pertussis protein
Buffer: 50 mM Tris, 5 mM DTT, 10 mM SrCl2, pH: 7.5
Experiment: SAXS data collected at BL4-2, Stanford Synchrotron Radiation Lightsource (SSRL) on 2024 Aug 1
Ion-selective conformational stabilization of a disordered repeats-in-toxin protein domain. Biophys J (2025)
Gudinas AP, Shambharkar GM, Chang MP, Fernández D, Matsui T, Mai DJ
RgGuinier 2.1 nm
Dmax 10.1 nm
VolumePorod 36 nm3

crTPpart2 of N-acetyl-gamma-glutamyl-phosphate reductase (ArgC)
crTPpart2 of N-acetyl-gamma-glutamyl-phosphate reductase (ArgC) experimental SAS data
The Paulinella chromatophore transit peptide part2 adopts a structural fold similar to the γ-glutamyl-cyclotransferase fold Plant Physiology 2025 Oct 10
Plant Physiology (2025 Oct 10)
Hemolysin A Type 1 Secretion System (Hly T1SS)
Alpha-hemolysin translocation ATP-binding protein HlyBHlyA (GFP-Hemolysin with Flag-Tag insertion)Membrane fusion protein (MFP) family protein (R14C; L229V)Outer membrane protein TolC experimental SAS data
Molecular Insights into CLD Domain Dynamics and Toxin Recruitment of the HlyA E. coli T1SS Journal of Molecular Biology 2025 Oct :169485
Journal of Molecular Biology :169485 (2025 Oct)
Multi-domain human O-GlcNAcase
Protein O-GlcNAcase experimental SAS data
Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms Nature Communications 2025 Oct 03 16(1)
Nature Communications 16(1) (2025 Oct 03)
Xylosyl- and glucuronyltransferase LARGE2 (LARGE2dTM) dimer treated with PNGase F enzyme
Xylosyl- and glucuronyltransferase LARGE2 experimental SAS data
LARGE1 processively polymerizes length-controlled matriglycan on prodystroglycan. Nat Commun 2025 Oct 10;16(1):9028
Nat Commun 16(1):9028 (2025 Oct 10)
Ca2+/calmodulin-dependent protein kinase II (CaMKII) holoenzyme with Exon 14 as the linker region
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ329-344) experimental SAS data
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation. Nat Commun 2025 Sep 26;16(1):8461
Nat Commun 16(1):8461 (2025 Sep 26)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.