Browse by MODEL: Ensemble

SASDQM8 – G. gallus TRPV4 intrinsically disordered N-terminus

Transient receptor potential cation channel subfamily V member 4 experimental SAS data
G. gallus TRPV4 intrinsically disordered N-terminus Rg histogram
Sample: Transient receptor potential cation channel subfamily V member 4 monomer, 15 kDa Gallus gallus protein
Buffer: 20 mM Tris, 100 mM NaCl, 10 mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Dec 16
Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity Nature Communications 14(1) (2023)
Goretzki B, Wiedemann C, McCray B, Schäfer S, Jansen J, Tebbe F, Mitrovic S, Nöth J, Cabezudo A, Donohue J, Jeffries C, Steinchen W, Stengel F, Sumner C, Hummer G, Hellmich U
RgGuinier 3.2 nm
Dmax 14.5 nm
VolumePorod 59 nm3

SASDQN8 – G. gallus TRPV4 intrinsically disordered N-terminus, mutation 107-KRWRR-111 to 107-AAWAA-111

Transient receptor potential cation channel subfamily V member 4 experimental SAS data
G. gallus TRPV4 intrinsically disordered N-terminus, mutation 107-KRWRR-111 to 107-AAWAA-111 Rg histogram
Sample: Transient receptor potential cation channel subfamily V member 4 monomer, 14 kDa Gallus gallus protein
Buffer: 20 mM Tris, 100 mM NaCl, 10 mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Dec 16
Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity Nature Communications 14(1) (2023)
Goretzki B, Wiedemann C, McCray B, Schäfer S, Jansen J, Tebbe F, Mitrovic S, Nöth J, Cabezudo A, Donohue J, Jeffries C, Steinchen W, Stengel F, Sumner C, Hummer G, Hellmich U
RgGuinier 3.3 nm
Dmax 14.5 nm
VolumePorod 37 nm3

SASDQJ8 – G. gallus TRPV4 N-terminal Domain, deletion mutant ∆N97

Transient receptor potential cation channel subfamily V member 4 experimental SAS data
G. gallus TRPV4 N-terminal Domain, deletion mutant ∆N97 Rg histogram
Sample: Transient receptor potential cation channel subfamily V member 4 monomer, 33 kDa Gallus gallus protein
Buffer: 20 mM Tris, 300 mM NaCl, 10 mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Mar 16
Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity Nature Communications 14(1) (2023)
Goretzki B, Wiedemann C, McCray B, Schäfer S, Jansen J, Tebbe F, Mitrovic S, Nöth J, Cabezudo A, Donohue J, Jeffries C, Steinchen W, Stengel F, Sumner C, Hummer G, Hellmich U
RgGuinier 2.5 nm
Dmax 11.9 nm
VolumePorod 41 nm3

SASDQH8 – G. gallus TRPV4 N-terminal Domain, deletion mutant ∆N54

Transient receptor potential cation channel subfamily V member 4 experimental SAS data
G. gallus TRPV4 N-terminal Domain, deletion mutant ∆N54 Rg histogram
Sample: Transient receptor potential cation channel subfamily V member 4 monomer, 37 kDa Gallus gallus protein
Buffer: 20 mM Tris, 300 mM NaCl, 10 mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Mar 16
Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity Nature Communications 14(1) (2023)
Goretzki B, Wiedemann C, McCray B, Schäfer S, Jansen J, Tebbe F, Mitrovic S, Nöth J, Cabezudo A, Donohue J, Jeffries C, Steinchen W, Stengel F, Sumner C, Hummer G, Hellmich U
RgGuinier 2.6 nm
Dmax 9.5 nm
VolumePorod 64 nm3

SASDSM2 – AtCP12-2 in an oxidized form

CP12-2 (D77G) experimental SAS data
AtCP12-2 in an oxidized form Rg histogram
Sample: CP12-2 (D77G) monomer, 8 kDa Arabidopsis thaliana protein
Buffer: 25 mM potassium phosphate, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2016 Feb 15
Conformational Disorder Analysis of the Conditionally Disordered Protein CP12 from Arabidopsis thaliana in Its Different Redox States International Journal of Molecular Sciences 24(11):9308 (2023)
Del Giudice A, Gurrieri L, Galantini L, Fanti S, Trost P, Sparla F, Fermani S
RgGuinier 2.0 nm
Dmax 9.0 nm
VolumePorod 10 nm3

SASDSN2 – AtCP12-2 in a reduced form

CP12-2 (D77G) experimental SAS data
AtCP12-2 in a reduced form Rg histogram
Sample: CP12-2 (D77G) monomer, 8 kDa Arabidopsis thaliana protein
Buffer: 25 mM potassium phosphate, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2016 Feb 15
Conformational Disorder Analysis of the Conditionally Disordered Protein CP12 from Arabidopsis thaliana in Its Different Redox States International Journal of Molecular Sciences 24(11):9308 (2023)
Del Giudice A, Gurrieri L, Galantini L, Fanti S, Trost P, Sparla F, Fermani S
RgGuinier 2.3 nm
Dmax 11.6 nm
VolumePorod 27 nm3

SASDR27 – Triple mutant (D116A, H118A, Y176A) of the D1-D2 N-terminal domains of thrombospondin type-1 domain-containing protein 7A

Thrombospondin type-1 domain-containing protein 7A (D116A, H118A, Y176A) experimental SAS data
Triple mutant (D116A, H118A, Y176A) of the D1-D2 N-terminal domains of thrombospondin type-1 domain-containing protein 7A Rg histogram
Sample: Thrombospondin type-1 domain-containing protein 7A (D116A, H118A, Y176A) monomer, 16 kDa Homo sapiens protein
Buffer: 25mM Tris, 150 mM NaCl, 5 mM NaNO3, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Dec 2
Structure of the N-terminal didomain d1_d2 of the Thrombospondin type-1 domain-containing 7A (2023)
Bochel A, Mortensen S, Seifert L, Hengel F, Jeffries C, Chojnowski G, Kretz O, Huber T, Tomas N, Wilmanns M
RgGuinier 2.7 nm
Dmax 11.5 nm
VolumePorod 19 nm3

SASDPA8 – Human apo NFU1 iron-sulfur cluster scaffold protein

NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (F118S, E168G) experimental SAS data
Human apo NFU1 iron-sulfur cluster scaffold protein Rg histogram
Sample: NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (F118S, E168G) monomer, 22 kDa Homo sapiens protein
Buffer: 50 mM phosphate, 150 mM NaCl, 5 mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2021 Mar 27
Structural plasticity of NFU1 upon interaction with binding partners: insights into the mitochondrial [4Fe-4S] cluster pathway Journal of Molecular Biology :168154 (2023)
Da Vela S, Saudino G, Lucarelli F, Banci L, Svergun D, Ciofi-Baffoni S
RgGuinier 2.4 nm
Dmax 9.3 nm
VolumePorod 32 nm3

SASDP99 – invariant surface glycoprotein ISG65

65 kDa invariant surface glycoprotein, putative experimental SAS data
invariant surface glycoprotein ISG65 Rg histogram
Sample: 65 kDa invariant surface glycoprotein, putative monomer, 41 kDa Trypanosoma brucei gambiense … protein
Buffer: 20 mM HEPES, 150 mM NaCl, 3% (v/v) glycerol, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2020 Nov 25
Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction. Nat Commun 14(1):2403 (2023)
Sülzen H, Began J, Dhillon A, Kereïche S, Pompach P, Votrubova J, Zahedifard F, Šubrtova A, Šafner M, Hubalek M, Thompson M, Zoltner M, Zoll S
RgGuinier 3.3 nm
Dmax 12.5 nm
VolumePorod 53 nm3

SASDQG4 – Rabies virus Nishigahara strain Phosphoprotein Isoform 3 (P3)

Isoform P3 of Phosphoprotein experimental SAS data
Rabies virus Nishigahara strain Phosphoprotein Isoform 3 (P3) Rg histogram
Sample: Isoform P3 of Phosphoprotein dimer, 55 kDa Rabies virus (strain … protein
Buffer: 25 mM HEPES, 150 mM NaCl, 1 mM TCEP, pH: 7.4
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2019 Jun 26
Structural insights into the multifunctionality of rabies virus P3 protein. Proc Natl Acad Sci U S A 120(14):e2217066120 (2023)
Sethi A, Rawlinson SM, Dubey A, Ang CS, Choi YH, Yan F, Okada K, Rozario AM, Brice AM, Ito N, Williamson NA, Hatters DM, Bell TDM, Arthanari H, Moseley GW, Gooley PR
RgGuinier 3.7 nm
Dmax 16.5 nm
VolumePorod 108 nm3