Small Angle Scattering Biological Data Bank SASBDB

Browse by MODEL: Hybrid

SASDPH4 – Alpha-1-glycoprotein at 343 K

Alpha-1-acid glycoprotein 1 experimental SAS data

Sample:	Alpha-1-acid glycoprotein 1 monomer, 22 kDa Homo sapiens protein
Buffer:	phosphate buffered saline, pH: 7.4
Experiment:	SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2021 Jan 12

SAXS data based glycosylated models of human alpha-1-acid glycorprotein, a key player in health, disease and drug circulation. J Biomol Struct Dyn :1-15 (2025)
Kalidas N, Peddada N, Pandey K, Ashish

R_g^Guinier	2.5	nm
D_max	7.5	nm
Volume^Porod	96	nm³

SASDVT5 – Marchantia polymorpha Auxin Response Factor 3

Auxin response factor experimental SAS data

Sample:	Auxin response factor monomer, 46 kDa Marchantia polymorpha protein
Buffer:	20 mM Tris-HCl, 150 mM NaCl, 1 mM DTT, pH: 8
Experiment:	SAXS data collected at BL11 - NCD, ALBA on 2019 Dec 3

The structure and function of the DNA binding domain of class B MpARF2 share more traits with class A AtARF5 than to that of class B AtARF1. Structure (2025)
Crespo I, Malfois M, Rienstra J, Tarrés-Solé A, van den Berg W, Weijers D, Boer DR

R_g^Guinier	2.6	nm
D_max	6.2	nm
Volume^Porod	59	nm³

SASDVU5 – Marchantia polymorpha Auxin Response Factor 3 in complex with high affinity DNA

Auxin response factorHigh Affinity ARF binding sequence inverted repeat with 6 nucleotide spacing experimental SAS data

Sample:	Auxin response factor monomer, 46 kDa Marchantia polymorpha protein High Affinity ARF binding sequence inverted repeat with 6 nucleotide spacing dimer, 12 kDa DNA
Buffer:	20 mM Tris-HCl, 150 mM NaCl, 1 mM DTT, pH: 8
Experiment:	SAXS data collected at BL11 - NCD, ALBA on 2019 Dec 3

R_g^Guinier	3.1	nm
D_max	8.4	nm
Volume^Porod	67	nm³

SASDSP8 – RNA Device 43 in ligand-free state (apo-D43)

RNA Device 43 in ligand-free state experimental SAS data

Sample:	RNA Device 43 in ligand-free state monomer, 40 kDa synthetic construct RNA
Buffer:	10 mM Bis-Tris, 100 mM KCl, and 1 mM MgCl2, pH: 6.8
Experiment:	SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2023 Jul 25

Structural investigation of an RNA device that regulates PD-1 expression in mammalian cells. Nucleic Acids Res 53(5) (2025)
Stagno JR, Deme JC, Dwivedi V, Lee YT, Lee HK, Yu P, Chen SY, Fan L, Degenhardt MFS, Chari R, Young HA, Lea SM, Wang YX

R_g^Guinier	3.4	nm
D_max	12.2	nm
Volume^Porod	58	nm³

SASDSQ8 – RNA Device 43 in ligand-bound state (holo-D43)

RNA Device 43 in ligand-bound state experimental SAS data

Sample:	RNA Device 43 in ligand-bound state monomer, 40 kDa synthetic construct RNA
Buffer:	10 mM Bis-Tris, 100 mM KCl, and 1 mM MgCl2, pH: 6.8
Experiment:	SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2023 Jul 25

R_g^Guinier	3.3	nm
D_max	12.1	nm
Volume^Porod	56	nm³

SASDWF4 – Outer membrane protein MIP from Legionella pneumophila (LpMIP) in complex with inhibitor NJS224

Outer membrane protein MIP(2S)‐2‐{[(2S)‐1‐[(4‐ fluorophenyl)methanesulfonyl]piperidin‐2‐ yl]formamido}‐4‐methyl‐N‐[(pyridin‐3‐ yl)methyl]pentanamide experimental SAS data

Sample:	Outer membrane protein MIP dimer, 46 kDa Legionella pneumophila subsp. … protein (2S)‐2‐{[(2S)‐1‐[(4‐ fluorophenyl)methanesulfonyl]piperidin‐2‐ yl]formamido}‐4‐methyl‐N‐[(pyridin‐3‐ yl)methyl]pentanamide monomer, 1 kDa
Buffer:	20 mM Tris, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2021 Nov 22

Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors. J Med Chem (2025)
Pérez Carrillo VH, Whittaker JJ, Wiedemann C, Harder JM, Lohr T, Jamithireddy AK, Dajka M, Goretzki B, Joseph B, Guskov A, Harmer NJ, Holzgrabe U, Hellmich UA

R_g^Guinier	2.9	nm
D_max	9.7	nm
Volume^Porod	61	nm³

SASDWG4 – Outer membrane protein MIP from Legionella pneumophila (LpMIP) in complex with inhibitor NJS227

Outer membrane protein MIP(2S)‐3‐(4‐fluorophenyl)‐2‐{[(2S)‐1‐[(4‐ fluorophenyl)methanesulfonyl]piperidin‐2‐ yl]formamido}‐N‐[(pyridin‐3‐yl)methyl]propanamide experimental SAS data

Sample:	Outer membrane protein MIP dimer, 46 kDa Legionella pneumophila subsp. … protein (2S)‐3‐(4‐fluorophenyl)‐2‐{[(2S)‐1‐[(4‐ fluorophenyl)methanesulfonyl]piperidin‐2‐ yl]formamido}‐N‐[(pyridin‐3‐yl)methyl]propanamide monomer, 1 kDa
Buffer:	20 mM Tris, 150 mM NaCl, pH: 7.5
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2021 Nov 22

R_g^Guinier	3.0	nm
D_max	10.0	nm
Volume^Porod	65	nm³

SASDVK4 – Immunoglobulin light chain AL55

Immunoglobulin light chain AL55 experimental SAS data

Sample:	Immunoglobulin light chain AL55 dimer, 47 kDa Homo sapiens protein
Buffer:	20 mM TrisHCL, 150 mM NaCl, pH: 8
Experiment:	SAXS data collected at BM29, ESRF on 2022 Jan 15

A conformational fingerprint for amyloidogenic light chains eLife 13 (2025)
Paissoni C, Puri S, Broggini L, Sriramoju M, Maritan M, Russo R, Speranzini V, Ballabio F, Nuvolone M, Merlini G, Palladini G, Hsu S, Ricagno S, Camilloni C

R_g^Guinier	2.6	nm
D_max	8.5	nm
Volume^Porod	61	nm³

SASDVL4 – Immunoglobulin light chain H3

Immunoglobulin light chain H3 experimental SAS data

Sample:	Immunoglobulin light chain H3 dimer, 45 kDa Homo sapiens protein
Buffer:	20 mM TrisHCL, 150 mM NaCl, pH: 8
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2018 May 12

R_g^Guinier	2.6	nm
D_max	8.4	nm
Volume^Porod	56	nm³

SASDVM4 – Immunoglobulin light chain H7

Immunoglobulin light chain H7 experimental SAS data

Sample:	Immunoglobulin light chain H7 dimer, 45 kDa Homo sapiens protein
Buffer:	20 mM TrisHCL, 150 mM NaCl, pH: 8
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2018 May 12

R_g^Guinier	2.5	nm
D_max	8.4	nm
Volume^Porod	54	nm³

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