Browse by MODEL: No model

SASDKD7 – Bromodomain-containing protein 3, BRD3, tandem bromodomains (1 mg/ml)

Bromodomain-containing protein 3 experimental SAS data
Bromodomain-containing protein 3 Kratky plot
Sample: Bromodomain-containing protein 3 monomer, 44 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, and 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2018 Sep 25
Multivalent nucleosome scaffolding by bromodomain and extraterminal domain tandem bromodomains. J Biol Chem :108289 (2025)
Olp MD, Bursch KL, Wynia-Smith SL, Nuñez R, Goetz CJ, Jackson V, Smith BC
RgGuinier 4.7 nm
Dmax 17.8 nm
VolumePorod 85 nm3

SASDKE7 – Bromodomain-containing protein 4, BRD4, tandem bromodomains (10 mg/ml)

Bromodomain-containing protein 4 experimental SAS data
Bromodomain-containing protein 4 Kratky plot
Sample: Bromodomain-containing protein 4 monomer, 48 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, and 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2018 Sep 25
Multivalent nucleosome scaffolding by bromodomain and extraterminal domain tandem bromodomains. J Biol Chem :108289 (2025)
Olp MD, Bursch KL, Wynia-Smith SL, Nuñez R, Goetz CJ, Jackson V, Smith BC
RgGuinier 7.3 nm
Dmax 20.2 nm
VolumePorod 150 nm3

SASDKF7 – Bromodomain-containing protein 4, BRD4, tandem bromodomains (5 mg/ml)

Bromodomain-containing protein 4 experimental SAS data
Bromodomain-containing protein 4 Kratky plot
Sample: Bromodomain-containing protein 4 monomer, 48 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, and 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2018 Sep 25
Multivalent nucleosome scaffolding by bromodomain and extraterminal domain tandem bromodomains. J Biol Chem :108289 (2025)
Olp MD, Bursch KL, Wynia-Smith SL, Nuñez R, Goetz CJ, Jackson V, Smith BC
RgGuinier 5.5 nm
Dmax 20.2 nm
VolumePorod 145 nm3

SASDKG7 – Bromodomain-containing protein 4, BRD4, tandem bromodomains (2 mg/ml)

Bromodomain-containing protein 4 experimental SAS data
Bromodomain-containing protein 4 Kratky plot
Sample: Bromodomain-containing protein 4 monomer, 48 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, and 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2018 Sep 25
Multivalent nucleosome scaffolding by bromodomain and extraterminal domain tandem bromodomains. J Biol Chem :108289 (2025)
Olp MD, Bursch KL, Wynia-Smith SL, Nuñez R, Goetz CJ, Jackson V, Smith BC
RgGuinier 5.2 nm
Dmax 20.1 nm
VolumePorod 100 nm3

SASDKH7 – Bromodomain testis-specific protein, BRDT, tandem bromodomains (10 mg/ml)

Bromodomain testis-specific protein experimental SAS data
Bromodomain testis-specific protein Kratky plot
Sample: Bromodomain testis-specific protein monomer, 42 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, and 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2018 Sep 25
Multivalent nucleosome scaffolding by bromodomain and extraterminal domain tandem bromodomains. J Biol Chem :108289 (2025)
Olp MD, Bursch KL, Wynia-Smith SL, Nuñez R, Goetz CJ, Jackson V, Smith BC
RgGuinier 5.7 nm
Dmax 18.6 nm
VolumePorod 120 nm3

SASDKJ7 – Bromodomain testis-specific protein, BRDT, tandem bromodomains (5 mg/ml)

Bromodomain testis-specific protein experimental SAS data
Bromodomain testis-specific protein Kratky plot
Sample: Bromodomain testis-specific protein monomer, 42 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, and 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2018 Sep 25
Multivalent nucleosome scaffolding by bromodomain and extraterminal domain tandem bromodomains. J Biol Chem :108289 (2025)
Olp MD, Bursch KL, Wynia-Smith SL, Nuñez R, Goetz CJ, Jackson V, Smith BC
RgGuinier 5.0 nm
Dmax 19.2 nm
VolumePorod 120 nm3

SASDKK7 – Transcription initiation factor TFIID subunit 1, TAF1, tandem bromodomains (2 mg/ml)

Transcription initiation factor TFIID subunit 1 experimental SAS data
Transcription initiation factor TFIID subunit 1 Kratky plot
Sample: Transcription initiation factor TFIID subunit 1 monomer, 31 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, and 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2018 Sep 25
Multivalent nucleosome scaffolding by bromodomain and extraterminal domain tandem bromodomains. J Biol Chem :108289 (2025)
Olp MD, Bursch KL, Wynia-Smith SL, Nuñez R, Goetz CJ, Jackson V, Smith BC
RgGuinier 3.2 nm
Dmax 9.9 nm
VolumePorod 80 nm3

SASDKL7 – Transcription initiation factor TFIID subunit 1, TAF1, tandem bromodomains (1 mg/ml)

Transcription initiation factor TFIID subunit 1 experimental SAS data
Transcription initiation factor TFIID subunit 1 Kratky plot
Sample: Transcription initiation factor TFIID subunit 1 monomer, 31 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, and 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2018 Sep 25
Multivalent nucleosome scaffolding by bromodomain and extraterminal domain tandem bromodomains. J Biol Chem :108289 (2025)
Olp MD, Bursch KL, Wynia-Smith SL, Nuñez R, Goetz CJ, Jackson V, Smith BC
RgGuinier 2.9 nm
Dmax 10.6 nm
VolumePorod 65 nm3

SASDGP2 – Thymine dioxygenase full length J-DNA binding protein (JBP1)

Thymine dioxygenase JBP1 experimental SAS data
Thymine dioxygenase JBP1 Kratky plot
Sample: Thymine dioxygenase JBP1 monomer, 93 kDa Leishmania tarentolae protein
Buffer: 20 mM HEPES, 200 mM NaCl, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2016 Feb 21
The domain architecture of protozoan protein J-DNA-binding protein 1 suggests synergy between base J DNA binding and thymidine hydroxylase activity. J Biol Chem (2019)
Adamopoulos A, Heidebrecht T, Roosendaal J, Touw WG, Phan IQ, Beijnen J, Perrakis A
RgGuinier 3.4 nm
Dmax 12.0 nm
VolumePorod 128 nm3

SASDGQ2 – Thymine dioxygenase lacking the JDNA binding domain Delta-JDBD (Δ-JDBD)

Delta-JDBD experimental SAS data
Delta-JDBD Kratky plot
Sample: Delta-JDBD monomer, 72 kDa Leismania tarentolae protein
Buffer: 20 mM HEPES, 200 mM NaCl, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2016 Feb 21
The domain architecture of protozoan protein J-DNA-binding protein 1 suggests synergy between base J DNA binding and thymidine hydroxylase activity. J Biol Chem (2019)
Adamopoulos A, Heidebrecht T, Roosendaal J, Touw WG, Phan IQ, Beijnen J, Perrakis A
RgGuinier 3.1 nm
Dmax 9.9 nm
VolumePorod 108 nm3