Browse by MODEL: No model

SASDU73 – Phosphorylated heterochromatin protein HP1α, delta CSD mutant, in 50 mM NaCl

phosphorylated Heterochromatin protein HP1α, delta CSD mutant experimental SAS data
phosphorylated Heterochromatin protein HP1α, delta CSD mutant Kratky plot
Sample: Phosphorylated Heterochromatin protein HP1α, delta CSD mutant monomer, 13 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 50 mM NaCl, 1 mM DTT, pH: 7
Experiment: SAXS data collected at BL-15A2, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2020 Nov 27
A dynamic structural unit of phase-separated heterochromatin protein 1α as revealed by integrative structural analyses Nucleic Acids Research 53(6) (2025)
Furukawa A, Yonezawa K, Negami T, Yoshimura Y, Hayashi A, Nakayama J, Adachi N, Senda T, Shimizu K, Terada T, Shimizu N, Nishimura Y
RgGuinier 3.0 nm
Dmax 14.4 nm
VolumePorod 44 nm3

SASDU83 – Phosphorylated heterochromatin protein HP1α, delta CSD b4 mutant, in 50 mM NaCl

phosphorylated Heterochromatin protein HP1α, delta CSD b4 mutant experimental SAS data
phosphorylated Heterochromatin protein HP1α, delta CSD b4 mutant Kratky plot
Sample: Phosphorylated Heterochromatin protein HP1α, delta CSD b4 mutant monomer, 13 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 50 mM NaCl, 1 mM DTT, pH: 7
Experiment: SAXS data collected at BL-15A2, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2020 Nov 27
A dynamic structural unit of phase-separated heterochromatin protein 1α as revealed by integrative structural analyses Nucleic Acids Research 53(6) (2025)
Furukawa A, Yonezawa K, Negami T, Yoshimura Y, Hayashi A, Nakayama J, Adachi N, Senda T, Shimizu K, Terada T, Shimizu N, Nishimura Y
RgGuinier 2.7 nm
Dmax 13.0 nm
VolumePorod 34 nm3

SASDUL4 – Signal transducer and activator of transcription 1-alpha/beta (STAT1)

Signal transducer and activator of transcription 1-alpha/beta experimental SAS data
Signal transducer and activator of transcription 1-alpha/beta Kratky plot
Sample: Signal transducer and activator of transcription 1-alpha/beta tetramer, 349 kDa Homo sapiens protein
Buffer: 10 mM HEPES-NaOH, 150 mM NaCl, 3% glycerol, 2 mM DTT, pH: 7.4
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2022 Dec 11
Structural analysis reveals how tetrameric tyrosine-phosphorylated STAT1 is targeted by the rabies virus P-protein Science Signaling 18(878) (2025)
Sugiyama A, Minami M, Ugajin K, Inaba-Inoue S, Yabuno N, Takekawa Y, Xiaomei S, Takei S, Sasaki M, Nomai T, Jiang X, Kita S, Maenaka K, Hirose M, Yao M, Gooley P, Moseley G, Sugita Y, Ose T
RgGuinier 6.2 nm
Dmax 21.2 nm
VolumePorod 800 nm3

SASDUM4 – Signal transducer and activator of transcription 1-alpha/beta bound to phosphoprotein (STAT1/RVP)

Signal transducer and activator of transcription 1-alpha/betaPhosphoprotein experimental SAS data
Signal transducer and activator of transcription 1-alpha/beta Phosphoprotein Kratky plot
Sample: Signal transducer and activator of transcription 1-alpha/beta tetramer, 349 kDa Homo sapiens protein
Phosphoprotein monomer, 33 kDa Rabies virus (strain … protein
Buffer: 10 mM HEPES-NaOH, 150 mM NaCl, 3% glycerol, 2 mM DTT, pH: 7.4
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2022 Dec 11
Structural analysis reveals how tetrameric tyrosine-phosphorylated STAT1 is targeted by the rabies virus P-protein Science Signaling 18(878) (2025)
Sugiyama A, Minami M, Ugajin K, Inaba-Inoue S, Yabuno N, Takekawa Y, Xiaomei S, Takei S, Sasaki M, Nomai T, Jiang X, Kita S, Maenaka K, Hirose M, Yao M, Gooley P, Moseley G, Sugita Y, Ose T
RgGuinier 6.5 nm
Dmax 26.0 nm
VolumePorod 857 nm3

SASDUN4 – Signal transducer and activator of transcription 1-alpha/beta bound to transducer/activator DNA (STAT1/DNA)

Signal transducer and activator of transcription 1-alpha/betaSignal transducer and activator of transcription 1 binding DNA experimental SAS data
Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 1 binding DNA Kratky plot
Sample: Signal transducer and activator of transcription 1-alpha/beta tetramer, 349 kDa Homo sapiens protein
Signal transducer and activator of transcription 1 binding DNA dimer, 11 kDa Homo sapiens DNA
Buffer: 10 mM HEPES-NaOH, 150 mM NaCl, 3% glycerol, 2 mM DTT, pH: 7.4
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2022 Dec 11
Structural analysis reveals how tetrameric tyrosine-phosphorylated STAT1 is targeted by the rabies virus P-protein Science Signaling 18(878) (2025)
Sugiyama A, Minami M, Ugajin K, Inaba-Inoue S, Yabuno N, Takekawa Y, Xiaomei S, Takei S, Sasaki M, Nomai T, Jiang X, Kita S, Maenaka K, Hirose M, Yao M, Gooley P, Moseley G, Sugita Y, Ose T
RgGuinier 6.1 nm
Dmax 19.4 nm
VolumePorod 761 nm3

SASDW44 – Immunoglobulin G4 (pH 2, 0.2 M NaCl), SEC-SAXS data

humanized immunoglobulin G4 monoclonal antibody (lebrikizumab) experimental SAS data
humanized immunoglobulin G4 monoclonal antibody (lebrikizumab) Kratky plot
Sample: Humanized immunoglobulin G4 monoclonal antibody (lebrikizumab) monomer, 148 kDa Mouse/human protein
Buffer: 100 mM glycine-HCl, 200 mM NaCl, pH: 2
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2024 Nov 19
IgG4 and IgG1 undergo common acid‐induced compaction into an alternatively folded state FEBS Letters (2025)
Imamura H, Honda S
RgGuinier 4.1 nm
Dmax 14.0 nm
VolumePorod 238 nm3

SASDW54 – Immunoglobulin G1 (pH 2, 0.2 M NaCl), SEC-SAXS data

humanized immunoglobulin G1 monoclonal antibody (trastuzumab) experimental SAS data
humanized immunoglobulin G1 monoclonal antibody (trastuzumab) Kratky plot
Sample: Humanized immunoglobulin G1 monoclonal antibody (trastuzumab) monomer, 148 kDa Mouse/human protein
Buffer: 100 mM glycine-HCl, 200 mM NaCl, pH: 2
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2023 May 20
IgG4 and IgG1 undergo common acid‐induced compaction into an alternatively folded state FEBS Letters (2025)
Imamura H, Honda S
RgGuinier 4.2 nm
Dmax 12.9 nm
VolumePorod 240 nm3

SASDW64 – Immunoglobulin G4 (pH 7)

humanized immunoglobulin G4 monoclonal antibody (lebrikizumab) experimental SAS data
humanized immunoglobulin G4 monoclonal antibody (lebrikizumab) Kratky plot
Sample: Humanized immunoglobulin G4 monoclonal antibody (lebrikizumab) monomer, 148 kDa Mouse/human protein
Buffer: 10 mM sodium phosphate, pH: 7
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2024 Nov 19
IgG4 and IgG1 undergo common acid‐induced compaction into an alternatively folded state FEBS Letters (2025)
Imamura H, Honda S
RgGuinier 4.8 nm
Dmax 15.6 nm
VolumePorod 211 nm3

SASDNX6 – ASO1 DNA in the absence of target RNA

LNA-DNA-LNA experimental SAS data
LNA-DNA-LNA Kratky plot
Sample: LNA-DNA-LNA monomer, 4 kDa DNA
Buffer: phosphate buffered saline, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2021 Oct 21
Application of enhanced biophysical strategies to determine ASO/target RNA binding affinity and kinetics
Michael Lerche
RgGuinier 1.3 nm
Dmax 4.0 nm
VolumePorod 4 nm3

SASDNZ6 – ASO3 RNA in the absence of target RNA

oME ASO experimental SAS data
oME ASO Kratky plot
Sample: OME ASO monomer, 4 kDa RNA
Buffer: phosphate buffered saline, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2021 Oct 21
Application of enhanced biophysical strategies to determine ASO/target RNA binding affinity and kinetics
Michael Lerche
RgGuinier 1.4 nm
Dmax 4.0 nm
VolumePorod 7 nm3