Browse by MACROMOLECULE type: nucleic acid

SASDRE2 – Gamma cyclodextrin - 25 mg/ml aqueous solution measured to 238 inverse nm

Gamma Cyclodextrin experimental SAS data
Gamma Cyclodextrin Kratky plot
Sample: Gamma Cyclodextrin monomer, 1 kDa
Buffer: water, pH: 7
Experiment: SAXS data collected at 11-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Nov 2
Extended q‐range X‐ray Scattering Reveals High‐Resolution Structural Details of Biomacromolecules in Aqueous Solutions Chemistry – A European Journal (2023)
Chen J, Borkiewicz O, Grishaev A, Zhang F, Bera M, Ruett U, Levin I
RgGuinier 0.7 nm

SASDRF2 – Gamma cyclodextrin - 12.5 mg/ml aqueous solution measured to 238 inverse nm

Gamma Cyclodextrin experimental SAS data
Gamma Cyclodextrin Kratky plot
Sample: Gamma Cyclodextrin monomer, 1 kDa
Buffer: water, pH: 7
Experiment: SAXS data collected at 11-ID-B, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Nov 2
Extended q‐range X‐ray Scattering Reveals High‐Resolution Structural Details of Biomacromolecules in Aqueous Solutions Chemistry – A European Journal (2023)
Chen J, Borkiewicz O, Grishaev A, Zhang F, Bera M, Ruett U, Levin I
RgGuinier 0.7 nm

SASDLS8 – Complex of Mtb GntR and Aptamer 1 [Rv0792c and Rv0792c_1]

Complex of Rv0792c and Rv0792c_1 experimental SAS data
OTHER model
Sample: Complex of Rv0792c and Rv0792c_1 monomer, 74 kDa
Buffer: 25 mM HEPES Buffer; 400 mM NaCl,, pH: 7.2
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2019 Oct 31
Structural and Functional Characterization of Rv0792c from Mycobacterium tuberculosis: Identifying Small Molecule Inhibitor against HutC Protein. Microbiol Spectr :e0197322 (2022)
Chauhan NK, Anand A, Sharma A, Dhiman K, Gosain TP, Singh P, Singh P, Khan E, Chattopadhyay G, Kumar A, Sharma D, Ashish, Sharma TK, Singh R
RgGuinier 3.6 nm
Dmax 12.0 nm

SASDLT8 – Complex of Mtb GntR and Aptamer 2 [Rv0792c and Rv0792c_2]

Complex of Rv0792c and Rv0792c_2 experimental SAS data
OTHER model
Sample: Complex of Rv0792c and Rv0792c_2 monomer, 46 kDa
Buffer: 25 mM HEPES Buffer; 400 mM NaCl,, pH: 7.2
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2019 Oct 31
Structural and Functional Characterization of Rv0792c from Mycobacterium tuberculosis: Identifying Small Molecule Inhibitor against HutC Protein. Microbiol Spectr :e0197322 (2022)
Chauhan NK, Anand A, Sharma A, Dhiman K, Gosain TP, Singh P, Singh P, Khan E, Chattopadhyay G, Kumar A, Sharma D, Ashish, Sharma TK, Singh R
RgGuinier 3.1 nm
Dmax 9.8 nm

SASDLU8 – Complex of Mtb GntR and Aptamer 5 [Rv0792c and Rv0792c_5]

Complex of GntR protein: Aptamer5 experimental SAS data
OTHER model
Sample: Complex of GntR protein: Aptamer5 monomer, 78 kDa
Buffer: 25 mM HEPES Buffer; 400 mM NaCl,, pH: 7.2
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2019 Oct 31
Structural and Functional Characterization of Rv0792c from Mycobacterium tuberculosis: Identifying Small Molecule Inhibitor against HutC Protein. Microbiol Spectr :e0197322 (2022)
Chauhan NK, Anand A, Sharma A, Dhiman K, Gosain TP, Singh P, Singh P, Khan E, Chattopadhyay G, Kumar A, Sharma D, Ashish, Sharma TK, Singh R
RgGuinier 3.4 nm
Dmax 12.0 nm

SASDLV8 – SS DNA Aptamer 5 which binds Mtb GntR Homolog [Rv0792c_5]

SSDNA Aptamer from SELEX against Mtb Rv0792c experimental SAS data
OTHER model
Sample: SSDNA Aptamer from SELEX against Mtb Rv0792c monomer, 14 kDa unidentified DNA
Buffer: 25 mM HEPES Buffer; 400 mM NaCl,, pH: 7.2
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2019 Oct 21
Structural and Functional Characterization of Rv0792c from Mycobacterium tuberculosis: Identifying Small Molecule Inhibitor against HutC Protein. Microbiol Spectr :e0197322 (2022)
Chauhan NK, Anand A, Sharma A, Dhiman K, Gosain TP, Singh P, Singh P, Khan E, Chattopadhyay G, Kumar A, Sharma D, Ashish, Sharma TK, Singh R
RgGuinier 1.8 nm
Dmax 7.1 nm

SASDLW8 – SS DNA Aptamer 2 which binds Mtb GntR Homolog [Rv0792c_2]

SSDNA Aptamer from SELEX against Mtb Rv0792c experimental SAS data
OTHER model
Sample: SSDNA Aptamer from SELEX against Mtb Rv0792c monomer, 13 kDa unidentified DNA
Buffer: 25 mM HEPES Buffer; 400 mM NaCl,, pH: 7.2
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2019 Oct 20
Structural and Functional Characterization of Rv0792c from Mycobacterium tuberculosis: Identifying Small Molecule Inhibitor against HutC Protein. Microbiol Spectr :e0197322 (2022)
Chauhan NK, Anand A, Sharma A, Dhiman K, Gosain TP, Singh P, Singh P, Khan E, Chattopadhyay G, Kumar A, Sharma D, Ashish, Sharma TK, Singh R
RgGuinier 1.9 nm
Dmax 7.6 nm

SASDLX8 – SS DNA Aptamer 1 which binds Mtb GntR Homolog [Rv0792c_1]

SSDNA Aptamer from SELEX against Mtb Rv0792c experimental SAS data
CHIMERA model
Sample: SSDNA Aptamer from SELEX against Mtb Rv0792c monomer, 13 kDa unidentified DNA
Buffer: 25 mM HEPES Buffer; 400 mM NaCl,, pH: 7.2
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2019 Oct 20
Structural and Functional Characterization of Rv0792c from Mycobacterium tuberculosis: Identifying Small Molecule Inhibitor against HutC Protein. Microbiol Spectr :e0197322 (2022)
Chauhan NK, Anand A, Sharma A, Dhiman K, Gosain TP, Singh P, Singh P, Khan E, Chattopadhyay G, Kumar A, Sharma D, Ashish, Sharma TK, Singh R
RgGuinier 2.1 nm
Dmax 8.6 nm

SASDLZ8 – SS DNA Aptamer 1 which binds Mtb GntR Homolog [Rv0792c_1]

SSDNA Aptamer from SELEX against Mtb Rv0792c experimental SAS data
DAMMIN model
Sample: SSDNA Aptamer from SELEX against Mtb Rv0792c monomer, 13 kDa unidentified DNA
Buffer: 25 mM HEPES Buffer; 400 mM NaCl,, pH: 7.2
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2019 Oct 20
Structural and Functional Characterization of Rv0792c from Mycobacterium tuberculosis: Identifying Small Molecule Inhibitor against HutC Protein. Microbiol Spectr :e0197322 (2022)
Chauhan NK, Anand A, Sharma A, Dhiman K, Gosain TP, Singh P, Singh P, Khan E, Chattopadhyay G, Kumar A, Sharma D, Ashish, Sharma TK, Singh R
RgGuinier 2.1 nm
Dmax 8.6 nm

SASDQL7 – Bicelles formed by DMPC DHPC

DHPC - 1,2-dihexanoyl-sn-glycero-3-phosphocholineDMPC - 1,2-dimyristoyl-sn-glycero-3-phosphocholine experimental SAS data
DHPC - 1,2-dihexanoyl-sn-glycero-3-phosphocholine DMPC - 1,2-dimyristoyl-sn-glycero-3-phosphocholine Kratky plot
Sample: DHPC - 1,2-dihexanoyl-sn-glycero-3-phosphocholine None, lipid
DMPC - 1,2-dimyristoyl-sn-glycero-3-phosphocholine None, lipid
Buffer: Tris buffered saline, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2021 Jun 1
Expanding the Toolbox for Bicelle-Forming Surfactant–Lipid Mixtures Molecules 27(21):7628 (2022)
Giudice R, Paracini N, Laursen T, Blanchet C, Roosen-Runge F, Cárdenas M