SASDN83 – Microtubule affinity regulating kinase (isoform MARK1)

Serine/threonine-protein kinase MARK1 experimental SAS data
CUSTOM IN-HOUSE model
Sample: Serine/threonine-protein kinase MARK1 monomer, 37 kDa Homo sapiens protein
Buffer: 0.1 M Bis-Tris, 0.2 M ammonium citrate, 1mM DTT, pH: 6.5
Experiment: SAXS data collected at EMBL X33, DORIS III on 2006 May 16
Structural Variations in the Catalytic and Ubiquitin-associated Domains of Microtubule-associated Protein/Microtubule Affinity Regulating Kinase (MARK) 1 and MARK2 Journal of Biological Chemistry 281(37):27586-27599 (2006)
Marx A, Nugoor C, Müller J, Panneerselvam S, Timm T, Bilang M, Mylonas E, Svergun D, Mandelkow E, Mandelkow E
RgGuinier 2.3 nm
Dmax 8.0 nm
VolumePorod 64 nm3

SASDM87 – Mouse ProNGF - pro-form of the NGF (nerve growth factor)

Mouse ProNGF - pro-form of the NGF (nerve growth factor) experimental SAS data
DAMMIN model
Sample: Mouse ProNGF - pro-form of the NGF (nerve growth factor) dimer, 100 kDa Mus musculus protein
Buffer: 50 mM Na-phosphate, pH: 7
Experiment: SAXS data collected at EMBL X33, DORIS III on 2005 Jul 18
Structural and functional properties of mouse proNGF. Biochem Soc Trans 34(Pt 4):605-6 (2006)
Paoletti F, Konarev PV, Covaceuszach S, Schwarz E, Cattaneo A, Lamba D, Svergun DI
RgGuinier 3.0 nm
Dmax 11.0 nm
VolumePorod 97 nm3

SASDAR4 – PTB full

Polypyrimidine tract-binding protein 1 experimental SAS data
BUNCH model
Sample: Polypyrimidine tract-binding protein 1 monomer, 57 kDa Homo sapiens protein
Buffer: 25 mM Tris 100 mM NaCl 5.0 mM DTT, pH: 7.2
Experiment: SAXS data collected at EMBL X33, DORIS III on 2004 Feb 11
Conformation of polypyrimidine tract binding protein in solution. Structure 14(6):1021-7 (2006)
Petoukhov MV, Monie TP, Allain FH, Matthews S, Curry S, Svergun DI
RgGuinier 4.0 nm
Dmax 16.5 nm

SASDN93 – Dystrophiamyotonica kinase (DMPK)

Myotonin-protein kinase experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Myotonin-protein kinase monomer, 92 kDa Homo sapiens protein
Buffer: 50 mM TrisHCl 50mM NaCl, 2.5 mM-mercaptoethanol, pH: 8
Experiment: SAXS data collected at EMBL X33, DORIS III on 2005 Mar 18
Molecular insights into the self‐assembly mechanism of dystrophia myotonica kinase The FASEB Journal 20(8):1142-1151 (2006)
Garcia P, Ucurum Z, Bucher R, Svergun D, Huber T, Lustig A, Konarev P, Marino M, Mayans O
RgGuinier 3.9 nm
Dmax 13.0 nm
VolumePorod 173 nm3

SASDAD4 – Full length GtBP3

full length CtBP3 experimental SAS data
DAMMIN model
Sample: full length CtBP3 tetramer, 170 kDa protein
Buffer: 25 mM Tris/HCl 250 mM NaCl, pH: 8
Experiment: SAXS data collected at EMBL X33, DORIS III on 2004 Nov 18
The C-terminal domain of the transcriptional corepressor CtBP is intrinsically unstructured. Protein Sci 15(5):1042-50 (2006)
Nardini M, Svergun D, Konarev PV, Spanò S, Fasano M, Bracco C, Pesce A, Donadini A, Cericola C, Secundo F, Luini A, Corda D, Bolognesi M
RgGuinier 5.1 nm
Dmax 19.0 nm
VolumePorod 330 nm3

SASDAE4 – C-terminal CtBP3

C-term part CtBP3 experimental SAS data
DAMMIN model
Sample: C-term part CtBP3 dimer, 52 kDa protein
Buffer: 25 mM Tris/HCl 250 mM NaCl, pH: 8
Experiment: SAXS data collected at EMBL X33, DORIS III on 2004 Nov 18
The C-terminal domain of the transcriptional corepressor CtBP is intrinsically unstructured. Protein Sci 15(5):1042-50 (2006)
Nardini M, Svergun D, Konarev PV, Spanò S, Fasano M, Bracco C, Pesce A, Donadini A, Cericola C, Secundo F, Luini A, Corda D, Bolognesi M
RgGuinier 5.5 nm
Dmax 20.0 nm
VolumePorod 126 nm3

SASDLP7 – Two-chain hepatocyte growth factor/scatter factor in complex with receptor tyrosine kinase MET

Hepatocyte growth factorHepatocyte growth factor receptor experimental SAS data
SASREF model
Sample: Hepatocyte growth factor monomer, 79 kDa Mus musculus protein
Hepatocyte growth factor receptor monomer, 100 kDa Mus musculus protein
Buffer: 50 mM MES, 150 mM NaCl, pH: 6.7
Experiment: SAXS data collected at EMBL X33, DORIS III on 2004 Feb 9
Structural basis of hepatocyte growth factor/scatter factor and MET signalling Proceedings of the National Academy of Sciences 103(11):4046-4051 (2006)
Gherardi E, Sandin S, Petoukhov M, Finch J, Youles M, Ofverstedt L, Miguel R, Blundell T, Vande Woude G, Skoglund U, Svergun D
RgGuinier 6.7 nm
Dmax 20.0 nm
VolumePorod 370 nm3

SASDLQ7 – receptor tyrosine kinase MET

Hepatocyte growth factor receptor experimental SAS data
SASREF model
Sample: Hepatocyte growth factor receptor monomer, 100 kDa Mus musculus protein
Buffer: 50 mM MES, 150 mM NaCl, pH: 6.7
Experiment: SAXS data collected at EMBL X33, DORIS III on 2004 Feb 7
Structural basis of hepatocyte growth factor/scatter factor and MET signalling Proceedings of the National Academy of Sciences 103(11):4046-4051 (2006)
Gherardi E, Sandin S, Petoukhov M, Finch J, Youles M, Ofverstedt L, Miguel R, Blundell T, Vande Woude G, Skoglund U, Svergun D
RgGuinier 4.8 nm
Dmax 16.0 nm
VolumePorod 190 nm3

SASDLQ5 – Tricorn protease oligomers

Tricorn protease experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Tricorn protease hexamer, 730 kDa Thermoplasma acidophilum (strain … protein
Buffer: 20mM Tris-HCl, 100 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL X33, DORIS III on 2003 Jan 14
X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum. J Biol Chem 280(39):33387-96 (2005)
Goettig P, Brandstetter H, Groll M, Göhring W, Konarev PV, Svergun DI, Huber R, Kim JS
RgGuinier 5.9 nm

SASDM77 – Full-length polypyrimidine tract binding protein (PTB)

Polypyrimidine tract-binding protein 2 experimental SAS data
DAMMIN model
Sample: Polypyrimidine tract-binding protein 2 monomer, 57 kDa Homo sapiens protein
Buffer: 25 mM Tris, 250 mM NaCl, 2 mM DTT, pH: 7.2
Experiment: SAXS data collected at EMBL X33, DORIS III on 2004 Feb 11
Structure and RNA interactions of the N-terminal RRM domains of PTB. Structure 12(9):1631-43 (2004)
Simpson PJ, Monie TP, Szendröi A, Davydova N, Tyzack JK, Conte MR, Read CM, Cary PD, Svergun DI, Konarev PV, Curry S, Matthews S
RgGuinier 4.0 nm
Dmax 14.0 nm
VolumePorod 117 nm3

2544 hits found.