SASDHA9 – Meiotic localizer of BRCA2 - MEILB2a1+2 dimer

Meiotic localizer of BRCA2 experimental SAS data
DAMMIF model
Sample: Meiotic localizer of BRCA2 dimer, 26 kDa Mus musculus protein
Buffer: 20 mM Tris pH 8.0, 150 mM KCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Oct 7
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells Nature Communications 11(1) (2020)
Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, Guo R, Pendlebury D, Alam I, Livera G, Emmanuelle M, Wang P, Nandakumar J, Davies O, Shibuya H
RgGuinier 4.6 nm
Dmax 16.0 nm
VolumePorod 88 nm3

SASDHB9 – Meiotic localizer of BRCA2 - MEILB2a1+2 octamer

Meiotic localizer of BRCA2 experimental SAS data
DAMMIF model
Sample: Meiotic localizer of BRCA2 octamer, 102 kDa Mus musculus protein
Buffer: 20 mM Tris pH 8.0, 150 mM KCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Oct 7
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells Nature Communications 11(1) (2020)
Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, Guo R, Pendlebury D, Alam I, Livera G, Emmanuelle M, Wang P, Nandakumar J, Davies O, Shibuya H
RgGuinier 5.7 nm
Dmax 20.0 nm
VolumePorod 368 nm3

SASDHC9 – Meiotic localizer of BRCA2 - MEILB1a2 monomer

Meiotic localizer of BRCA2 experimental SAS data
DAMMIF model
Sample: Meiotic localizer of BRCA2 monomer, 9 kDa Mus musculus protein
Buffer: 20 mM Tris pH 8.0, 150 mM KCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Oct 7
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells Nature Communications 11(1) (2020)
Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, Guo R, Pendlebury D, Alam I, Livera G, Emmanuelle M, Wang P, Nandakumar J, Davies O, Shibuya H
RgGuinier 3.0 nm
Dmax 11.0 nm
VolumePorod 43 nm3

SASDGG2 – Interleukin 11 receptor subunit alpha

Interleukin-11 receptor subunit alpha experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Interleukin-11 receptor subunit alpha monomer, 32 kDa Homo sapiens protein
Buffer: 20 mM Tris, 150 mM NaCl, 0.2% sodium azide, pH: 8.5
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2019 Jun 8
The structure of the extracellular domains of human interleukin 11 α-receptor reveals mechanisms of cytokine engagement Journal of Biological Chemistry :jbc.RA119.012351 (2020)
Metcalfe R, Aizel K, Zlatic C, Nguyen P, Morton C, Lio D, Cheng H, Dobson R, Parker M, Gooley P, Putoczki T, Griffin M
RgGuinier 3.0 nm
Dmax 9.5 nm
VolumePorod 41 nm3

SASDGH2 – Interleukin 11, N-terminally truncated

Interleukin 11 experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Interleukin 11 monomer, 18 kDa Homo sapiens protein
Buffer: 20 mM Tris, 150 mM NaCl, 0.2% sodium azide, pH: 8.5
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2019 Jun 8
The structure of the extracellular domains of human interleukin 11 α-receptor reveals mechanisms of cytokine engagement Journal of Biological Chemistry :jbc.RA119.012351 (2020)
Metcalfe R, Aizel K, Zlatic C, Nguyen P, Morton C, Lio D, Cheng H, Dobson R, Parker M, Gooley P, Putoczki T, Griffin M
RgGuinier 1.7 nm
Dmax 5.4 nm
VolumePorod 22 nm3

SASDGJ2 – Interleukin 11, full length

Interleukin 11 experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Interleukin 11 monomer, 19 kDa Homo sapiens protein
Buffer: 20 mM Tris, 150 mM NaCl, 0.2% sodium azide, pH: 8.5
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2019 Jun 8
The structure of the extracellular domains of human interleukin 11 α-receptor reveals mechanisms of cytokine engagement Journal of Biological Chemistry :jbc.RA119.012351 (2020)
Metcalfe R, Aizel K, Zlatic C, Nguyen P, Morton C, Lio D, Cheng H, Dobson R, Parker M, Gooley P, Putoczki T, Griffin M
RgGuinier 1.9 nm
Dmax 6.1 nm
VolumePorod 28 nm3

SASDGK2 – Interleukin 11/Interleukin 11 receptor alpha complex

Interleukin-11 receptor subunit alphaInterleukin 11 experimental SAS data
OTHER model
Sample: Interleukin-11 receptor subunit alpha monomer, 32 kDa Homo sapiens protein
Interleukin 11 monomer, 18 kDa Homo sapiens protein
Buffer: 20 mM Tris, 150 mM NaCl, 0.2% sodium azide, pH: 8.5
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2019 Jun 8
The structure of the extracellular domains of human interleukin 11 α-receptor reveals mechanisms of cytokine engagement Journal of Biological Chemistry :jbc.RA119.012351 (2020)
Metcalfe R, Aizel K, Zlatic C, Nguyen P, Morton C, Lio D, Cheng H, Dobson R, Parker M, Gooley P, Putoczki T, Griffin M
RgGuinier 3.3 nm
Dmax 10.2 nm
VolumePorod 84 nm3

SASDHR9 – GntR-type transcriptional regulator NanR from Escherichia coli

HTH-type transcriptional repressor NanR experimental SAS data
CUSTOM IN-HOUSE model
Sample: HTH-type transcriptional repressor NanR dimer, 59 kDa Escherichia coli protein
Buffer: 20 mM Tris, 150 mM NaCl, 0.1 % (w/v) sodium azide, pH: 8
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2019 Apr 20
Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism (2020)
Horne C, Venugopal H, Panjikar S, Henrickson A, Brookes E, North R, Murphy J, Friemann R, Griffin M, Ramm G, Demeler B, Dobson R
RgGuinier 3.2 nm
Dmax 10.5 nm
VolumePorod 110 nm3

SASDHS9 – GntR-type transcriptional regulator NanR from Escherichia coli in the presence of N-acetylneuraminic acid

HTH-type transcriptional repressor NanR experimental SAS data
CUSTOM IN-HOUSE model
Sample: HTH-type transcriptional repressor NanR dimer, 59 kDa Escherichia coli protein
Buffer: 20 mM Tris, 150 mM NaCl, 20 mM Neu5Ac and 0.1 % (w/v) sodium azide, pH: 8
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2019 Apr 20
Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism (2020)
Horne C, Venugopal H, Panjikar S, Henrickson A, Brookes E, North R, Murphy J, Friemann R, Griffin M, Ramm G, Demeler B, Dobson R
RgGuinier 3.1 nm
Dmax 10.1 nm
VolumePorod 105 nm3

SASDHT9 – Dimeric NanR-DNA hetero-complex from Escherichia coli

HTH-type transcriptional repressor NanR(GGTATA)2 repeat DNA experimental SAS data
CUSTOM IN-HOUSE model
Sample: HTH-type transcriptional repressor NanR dimer, 59 kDa Escherichia coli protein
(GGTATA)2 repeat DNA monomer, 11 kDa DNA
Buffer: 20 mM Tris, 150 mM NaCl, 0.1 % (w/v) sodium azide, pH: 8
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2019 Apr 20
Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism (2020)
Horne C, Venugopal H, Panjikar S, Henrickson A, Brookes E, North R, Murphy J, Friemann R, Griffin M, Ramm G, Demeler B, Dobson R
RgGuinier 3.3 nm
Dmax 9.8 nm
VolumePorod 108 nm3

4781 hits found.