SASDDR4 – LIM/homeobox protein Lhx4 LIM domains fused to the LIM interaction domain (LID) R282G mutant of Insulin gene enhancer protein ISL-2

LIM/homeobox protein Lhx4Insulin gene enhancer protein ISL-2 (R282G) experimental SAS data
DAMMIN model
Sample: LIM/homeobox protein Lhx4 monomer, 15 kDa Mus musculus protein
Insulin gene enhancer protein ISL-2 (R282G) monomer, 4 kDa Mus musculus protein
Buffer: 20 mM Tris, 150 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2015 Nov 19
Mutation in a flexible linker modulates binding affinity for modular complexes. Proteins (2019)
Stokes PH, Robertson NO, Silva AP, Estephan T, Trewhella J, Guss JM, Matthews JM
RgGuinier 2.3 nm
Dmax 8.5 nm
VolumePorod 21 nm3

SASDES5 – Neurotrypsin Scavenger Receptor Cysteine-Rich Domain 3 (mmNT-SRCR3) - from SEC-SAXS

Mouse Neurotrypsin Scavenger Receptor Cysteine-Rich Domain 3 experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Mouse Neurotrypsin Scavenger Receptor Cysteine-Rich Domain 3 monomer, 13 kDa Mus musculus protein
Buffer: 25 mM HEPES, 0.1 M NaCl, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2017 May 20
Structural characterization of the third scavenger receptor cysteine-rich domain of murine neurotrypsin. Protein Sci 28(4):746-755 (2019)
Canciani A, Catucci G, Forneris F
RgGuinier 1.5 nm
Dmax 4.5 nm
VolumePorod 24 nm3

SASDQP6 – Nanodisc with POPC and circularized membrane scaffolding protein (csMSP1E3D1)

circularized Membrane scaffolding protein 1 E3 D11-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) experimental SAS data
OTHER [STATIC IMAGE] model
Sample: circularized Membrane scaffolding protein 1 E3 D1 , 62 kDa protein
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) None, lipid
Buffer: 20 mM Tris-HCl pH 7.5, 100 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 5
Circularized and solubility‐enhanced MSP s facilitate simple and high‐yield production of stable nanodiscs for studies of membrane proteins in solution The FEBS Journal 286(9):1734-1751 (2019)
Johansen N, Tidemand F, Nguyen T, Rand K, Pedersen M, Arleth L
RgGuinier 5.8 nm
Dmax 14.5 nm

SASDD33 – Toxin/Antitoxin complex from M. tuberculosis

Mycobacterial cidal toxinMycobacterial cidal antitoxin experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Mycobacterial cidal toxin hexamer, 121 kDa Mycobacterium tuberculosis protein
Mycobacterial cidal antitoxin hexamer, 76 kDa Mycobacterium tuberculosis protein
Buffer: 100 mM HEPES, 100 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2015 Jun 2
An NAD+ Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death. Mol Cell (2019)
Freire DM, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V, Cianci M, Tuukkanen A, Boudehen YM, Peixoto A, Botella L, Svergun DI, Schn...
RgGuinier 4.1 nm
Dmax 11.4 nm
VolumePorod 262 nm3

SASDKM7 – Sulfite reductase flavoprotein-60

Sulfite reductase [NADPH] flavoprotein alpha-component (Assimilatory NADPH-dependent sulfite reductase flavoprotein) experimental SAS data
Sample: Sulfite reductase [NADPH] flavoprotein alpha-component (Assimilatory NADPH-dependent sulfite reductase flavoprotein) monomer, 61 kDa Escherichia coli (strain … protein
Buffer: 50 mM KPi, 100 mM NaCl, 1 mM EDTA, pH: 7.8
Experiment: SANS data collected at EQ-SANS (BL-6), Spallation Neutron Source on 2018 Jul 11
NADPH-dependent sulfite reductase flavoprotein adopts an extended conformation unique to this diflavin reductase Journal of Structural Biology 205(2):170-179 (2019)
Tavolieri A, Murray D, Askenasy I, Pennington J, McGarry L, Stanley C, Stroupe M
RgGuinier 3.2 nm
Dmax 11.6 nm
VolumePorod 60 nm3

SASDKN7 – Sulfite reductase flavoprotein-60-ΔAAPSQS

Sulfite reductase [NADPH] flavoprotein alpha-component (Assimilatory NADPH-dependent sulfite reductase flavoprotein) experimental SAS data
Sample: Sulfite reductase [NADPH] flavoprotein alpha-component (Assimilatory NADPH-dependent sulfite reductase flavoprotein) monomer, 61 kDa Escherichia coli (strain … protein
Buffer: 50 mM KPi, 100 mM NaCl, 1 mM EDTA, pH: 7.8
Experiment: SANS data collected at EQ-SANS (BL-6), Spallation Neutron Source on 2018 Jul 11
NADPH-dependent sulfite reductase flavoprotein adopts an extended conformation unique to this diflavin reductase Journal of Structural Biology 205(2):170-179 (2019)
Tavolieri A, Murray D, Askenasy I, Pennington J, McGarry L, Stanley C, Stroupe M
RgGuinier 3.2 nm
Dmax 11.3 nm
VolumePorod 73 nm3

SASDE78 – Solution structure of the diadenylate cyclase/phosphoglucosamine mutase (DacA/GlmM) complex from Staphylococcus aureus

Diadenylate cyclasePhosphoglucosamine mutase experimental SAS data
DAMFILT model
Sample: Diadenylate cyclase dimer, 39 kDa Staphylococcus aureus protein
Phosphoglucosamine mutase dimer, 99 kDa Staphylococcus aureus protein
Buffer: 30 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 7
Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM. PLoS Pathog 15(1):e1007537 (2019)
Tosi T, Hoshiga F, Millership C, Singh R, Eldrid C, Patin D, Mengin-Lecreulx D, Thalassinos K, Freemont P, Gründling A
RgGuinier 3.9 nm
Dmax 12.1 nm
VolumePorod 204 nm3

SASDE88 – Solution structure of phosphoglucosamine mutase (GlmM) from Staphylococcus aureus

Phosphoglucosamine mutase experimental SAS data
DAMFILT model
Sample: Phosphoglucosamine mutase dimer, 99 kDa Staphylococcus aureus protein
Buffer: 30 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 7
Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM. PLoS Pathog 15(1):e1007537 (2019)
Tosi T, Hoshiga F, Millership C, Singh R, Eldrid C, Patin D, Mengin-Lecreulx D, Thalassinos K, Freemont P, Gründling A
RgGuinier 3.7 nm
Dmax 12.5 nm
VolumePorod 134 nm3

SASDE98 – Solution structure of Diadenylate cyclase (DacA) from Staphylococcus aureus

Diadenylate cyclase experimental SAS data
DAMFILT model
Sample: Diadenylate cyclase dimer, 39 kDa Staphylococcus aureus protein
Buffer: 30 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 May 7
Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM. PLoS Pathog 15(1):e1007537 (2019)
Tosi T, Hoshiga F, Millership C, Singh R, Eldrid C, Patin D, Mengin-Lecreulx D, Thalassinos K, Freemont P, Gründling A
RgGuinier 2.6 nm
Dmax 8.6 nm
VolumePorod 57 nm3

SASDEJ3 – Truncated neutophil cytosol factor 1, p47phox [1-342]

Neutophil cytosol factor 1 experimental SAS data
OTHER model
Sample: Neutophil cytosol factor 1 monomer, 40 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM EDTA, 2 mM DTT, 5% glycerol, pH: 7.5
Experiment: SAXS data collected at Bruker Nanostar, IBBMC on 2009 Oct 16
Quantitative live-cell imaging and 3D modeling reveal critical functional features in the cytosolic complex of phagocyte NADPH oxidase. J Biol Chem (2019)
Ziegler CS, Bouchab L, Tramier M, Durand D, Fieschi F, Dupré-Crochet S, Mérola F, Nüße O, Erard M
RgGuinier 2.6 nm
Dmax 10.0 nm
VolumePorod 58 nm3

4692 hits found.