Schistosoma mansoni Venom Allergen-like protein 11 (SmVAL11) in complex with cognate polyclonal antibody (pAb anti-SmVAL11)

Adriana Erica Miele

Submitted to SASBDB: 2026 May 18 Published in SASBDB: 2026 Jul 28

SASDZA8 – Polyclonal antibody anti-SmVAL11 Sample: Polyclonal antibody anti-SmVAL11 monomer, 140 kDa Lagomorph protein Buffer: 25 mM MES, 125 mM NaCl, 1 mM EDTA, pH: 6.8 Experiment: SAXS data collected at SWING, SOLEIL on 2025 Jan 22 RgGuinier 4.7 nm Dmax 16.4 nm VolumePorod 193 nm3

SASDZB8 – Schistosoma mansoni Venom Allergen-like protein isoform 11 (SmVAL11) in complex with pAb anti-SmVAL11, ratio 2:1 (2nd peak) Sample: Venom Allergen-like protein 11, 47 kDa Schistosoma mansoni protein Polyclonal antibody anti-SmVAL11 monomer, 140 kDa Lagomorph protein Buffer: 25 mM MES, 125 mM NaCl, 1 mM EDTA, pH: 6.8 Experiment: SAXS data collected at SWING, SOLEIL on 2025 Jan 22 RgGuinier 4.9 nm Dmax 17.2 nm VolumePorod 206 nm3

SASDZC8 – Schistosoma mansoni Venom Allergen-like protein isoform 11 (SmVAL11) in complex with pAb anti-SmVAL11, ratio 2:1 (1st peak) Sample: Venom Allergen-like protein 11, 47 kDa Schistosoma mansoni protein Polyclonal antibody anti-SmVAL11 monomer, 140 kDa Lagomorph protein Buffer: 25 mM MES, 125 mM NaCl, 1 mM EDTA, pH: 6.8 Experiment: SAXS data collected at SWING, SOLEIL on 2025 Jan 22 RgGuinier 7.9 nm Dmax 33.2 nm VolumePorod 688 nm3

SASDZD8 – Schistosoma mansoni Venom Allergen-like protein isoform 11 (SmVAL11) in complex with pAb anti-SmVAL11, ratio 1:1 (2nd peak) Sample: Venom Allergen-like protein 11, 47 kDa Schistosoma mansoni protein Polyclonal antibody anti-SmVAL11 monomer, 140 kDa Lagomorph protein Buffer: 25 mM MES, 125 mM NaCl, 1 mM EDTA, pH: 6.8 Experiment: SAXS data collected at SWING, SOLEIL on 2025 Jan 22 RgGuinier 4.9 nm Dmax 16.4 nm VolumePorod 204 nm3

SASDZE8 – Schistosoma mansoni Venom Allergen-like protein isoform 11 (SmVAL11) in complex with pAb anti-SmVAL11, ratio 1:1 (1st peak) Sample: Venom Allergen-like protein 11, 47 kDa Schistosoma mansoni protein Polyclonal antibody anti-SmVAL11 monomer, 140 kDa Lagomorph protein Buffer: 25 mM MES, 125 mM NaCl, 1 mM EDTA, pH: 6.8 Experiment: SAXS data collected at SWING, SOLEIL on 2025 Jan 22 RgGuinier 8.2 nm Dmax 35.6 nm VolumePorod 640 nm3

SASDZF8 – Schistosoma mansoni Venom Allergen-like protein isoform 11 (SmVAL11) in complex with pAb anti-SmVAL11, ratio 0.5:1 (2nd peak) Sample: Venom Allergen-like protein 11, 47 kDa Schistosoma mansoni protein Polyclonal antibody anti-SmVAL11 monomer, 140 kDa Lagomorph protein Buffer: 25 mM MES, 125 mM NaCl, 1 mM EDTA, pH: 6.8 Experiment: SAXS data collected at SWING, SOLEIL on 2025 Jan 22 RgGuinier 4.8 nm Dmax 16.1 nm VolumePorod 194 nm3

SASDZG8 – Schistosoma mansoni Venom Allergen-like protein isoform 11 (SmVAL11) in complex with pAb anti-SmVAL11, ratio 0.5:1 (1st peak) Sample: Venom Allergen-like protein 11, 47 kDa Schistosoma mansoni protein Polyclonal antibody anti-SmVAL11 monomer, 140 kDa Lagomorph protein Buffer: 25 mM MES, 125 mM NaCl, 1 mM EDTA, pH: 6.8 Experiment: SAXS data collected at SWING, SOLEIL on 2025 Jan 22 RgGuinier 8.6 nm Dmax 42.7 nm VolumePorod 573 nm3

SASDZH8 – Schistosoma mansoni Venom Allergen-like protein isoform 11 (SmVAL11) - Full length Sample: Venom Allergen-like protein 11, 47 kDa Schistosoma mansoni protein Buffer: 25 mM MES, 125 mM NaCl, 1 mM EDTA, pH: 6.8 Experiment: SAXS data collected at SWING, SOLEIL on 2024 Jul 11 RgGuinier 3.9 nm Dmax 18.0 nm VolumePorod 59 nm3

SASDZJ8 – Schistosoma mansoni Venom Allergen-like protein isoform 11 (SmVAL11) - Cleaved domains Sample: Venom Allergen-like protein 11, 47 kDa Schistosoma mansoni protein Buffer: 25 mM MES, 125 mM NaCl, 1 mM EDTA, pH: 6.8 Experiment: SAXS data collected at SWING, SOLEIL on 2024 Jul 11 RgGuinier 2.2 nm Dmax 7.0 nm VolumePorod 20 nm3