The dynamic nature of the conserved tegument protein UL37 of herpesviruses.

Koenigsberg AL, Heldwein EE
J Biol Chem 293(41):15827-15839 (2018 Oct 12)

PMID: 30166339 doi: 10.1074/jbc.RA118.004481

Submitted to SASBDB: 2018 Jul 16 Published in SASBDB: 2018 Sep 7

SASDDQ9 – N-terminal half of herpes simplex virus type-1 inner tegument protein UL37 Sample: Inner tegument protein monomer, 62 kDa Human alphaherpesvirus 1 protein Buffer: 100 mM HEPES 150 mM NaCl 5% glycerol 0.1 mM tris(2-carboxyethyl)phosphine (TCEP), pH: 7.5 Experiment: SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2017 Jun 3 RgGuinier 3.3 nm Dmax 10.4 nm VolumePorod 91 nm3

SASDDP9 – C-terminal half of pseudorabies virus tegument protein UL37 Sample: Tegument protein UL37 monomer, 49 kDa Suid alphaherpesvirus 1 protein Buffer: 100 mM HEPES 150 mM NaCl 5% glycerol 0.1 mM tris(2-carboxyethyl)phosphine (TCEP), pH: 7.5 Experiment: SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2017 Jun 3 RgGuinier 4.2 nm Dmax 14.0 nm VolumePorod 71 nm3

SASDEL4 – Residues 478-884 of pseudorabies virus tegument protein UL37 Sample: Tegument protein UL37 monomer, 43 kDa Suid alphaherpesvirus 1 protein Buffer: 100 mM HEPES 150 mM NaCl 5% glycerol 0.1 mM tris(2-carboxyethyl)phosphine (TCEP), pH: 7.5 Experiment: SAXS data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2017 Jun 3 RgGuinier 3.9 nm Dmax 12.5 nm