Small Angle Scattering Biological Data Bank SASBDB


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7 hits found for Yong-Sheng Wang

SASDTP2 – Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) wild type

Ubiquitin carboxyl-terminal hydrolase isozyme L1 experimental SAS data

Ubiquitin carboxyl-terminal hydrolase isozyme L1 Kratky plot

Sample:	Ubiquitin carboxyl-terminal hydrolase isozyme L1 monomer, 26 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.03% NaN3, pH: 7.5
Experiment:	SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 Sep 2

Altered protein dynamics and a more reactive catalytic cysteine in a neurodegeneration-associated UCHL1 mutant. J Mol Biol :168438 (2024)
...Wang YS, Flaherty DP, Danny Hsu ST, Das C

R_g^Guinier	1.9	nm
D_max	5.9	nm
Volume^Porod	26	nm³

SASDTQ2 – Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) R178Q mutant

Ubiquitin carboxyl-terminal hydrolase isozyme L1 (R178Q) experimental SAS data

Ubiquitin carboxyl-terminal hydrolase isozyme L1 (R178Q) Kratky plot

Sample:	Ubiquitin carboxyl-terminal hydrolase isozyme L1 (R178Q) monomer, 26 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.03% NaN3, pH: 7.5
Experiment:	SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 Sep 2

Altered protein dynamics and a more reactive catalytic cysteine in a neurodegeneration-associated UCHL1 mutant. J Mol Biol :168438 (2024)
...Wang YS, Flaherty DP, Danny Hsu ST, Das C

R_g^Guinier	1.9	nm
D_max	5.8	nm
Volume^Porod	25	nm³

SASDV53 – Fc-fused PTPRA ECD in PBS buffer

Receptor-type tyrosine-protein phosphatase alpha experimental SAS data

Sample:	Receptor-type tyrosine-protein phosphatase alpha dimer, 150 kDa Homo sapiens protein
Buffer:	10 mM phosphate, 137 mM NaCl, 2.7 mM KCl, pH: 7.4
Experiment:	SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2021 Aug 19

High Density of N- and O-Glycosylation Shields and Defines the Structural Dynamics of the Intrinsically Disordered Ectodomain of Receptor-type Protein Tyrosine Phosphatase Alpha JACS Au (2023)
...Wang Y, Sridharan D, Kuo C, Chien C, Uchihashi T, Kato K, Angata T, Meng T, Hsu S, Khoo K

R_g^Guinier	8.3	nm
D_max	35.3	nm

SASDT35 – N-cadherin extracellular domains EC1-EC5

Sample:	Cadherin-2 dimer, 123 kDa Mus musculus protein
Buffer:	20 mM HEPES, 150 mM NaCl, 3 mM CaCl2, 0.02% NaN3, pH: 7.5
Experiment:	SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 May 1

Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries. Cell 187(5):1296-1311.e26 (2024)
...Wang YS, Hsu MF, Khoo KH, Hummer G, Hsu SD, Hanus C, Sikora M

R_g^Guinier	8.8	nm
D_max	40.0	nm
Volume^Porod	496	nm³

SASDT45 – N-cadherin extracellular domains EC4-EC5

Sample:	Cadherin-2 monomer, 24 kDa Mus musculus protein
Buffer:	20 mM HEPES, 150 mM NaCl, 3 mM CaCl2, 0.02% NaN3, pH: 7.5
Experiment:	SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 May 1

R_g^Guinier	3.4	nm
D_max	12.6	nm
Volume^Porod	63	nm³

SASDXD6 – Ubiquitin C-terminal hydrolase (UCH) domain of BAP1

Ubiquitin C-terminal hydrolase (UCH) domain of BAP1 wild type experimental SAS data

Ubiquitin C-terminal hydrolase (UCH) domain of BAP1 wild type Kratky plot

Sample:	Ubiquitin C-terminal hydrolase (UCH) domain of BAP1 wild type monomer, 27 kDa protein
Buffer:	20 mM HEPES, 150 mM NaCl, 3 mM CaCl2, 0.02% NaN3, pH: 7.5
Experiment:	SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2024 Jun 23

Allosteric network of dynamic coupling within BAP1-UCH revealed by methyl NMR
Yong-Sheng Wang

R_g^Guinier	2.1	nm
D_max	8.0	nm
Volume^Porod	35	nm³

SASDXE6 – Ubiquitin C-terminal hydrolase (UCH) domain of BAP1 point mutation (L49V)

Ubiquitin C-terminal hydrolase (UCH) domain of BAP1 L49V experimental SAS data

Ubiquitin C-terminal hydrolase (UCH) domain of BAP1 L49V Kratky plot

Sample:	Ubiquitin C-terminal hydrolase (UCH) domain of BAP1 L49V monomer, 27 kDa protein
Buffer:	20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.02% NaN3, pH: 7.5
Experiment:	SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2024 Jun 23