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8 hits found for Microtubule-associated protein tau

SASDLS4 – Tau35, C-terminal fragment of human Tau protein

Microtubule-associated protein tau, Tau35 fragment experimental SAS data
Tau35, C-terminal fragment of human Tau protein Rg histogram
Sample: Microtubule-associated protein tau, Tau35 fragment monomer, 27 kDa Homo sapiens protein
Buffer: phosphate buffered saline, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Oct 8
...Tau35 Fragment has an Increased Propensity to Aggregate Compared to Full-Length Tau Frontiers in Molecular Biosciences 8 (2021)
Lyu C, Da Vela S, Al-Hilaly Y, Marshall K, Thorogate R, Svergun D, Serpell L, Pastore A, Hanger D
RgGuinier 4.6 nm
Dmax 16.2 nm
VolumePorod 93 nm3

SASDLT4 – Tau protein, 2N3R isoform

Microtubule-associated protein tau, 2N3R isoform experimental SAS data
Tau protein, 2N3R isoform Rg histogram
Sample: Microtubule-associated protein tau, 2N3R isoform monomer, 43 kDa Homo sapiens protein
Buffer: phosphate buffered saline, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Oct 8
...Tau35 Fragment has an Increased Propensity to Aggregate Compared to Full-Length Tau Frontiers in Molecular Biosciences 8 (2021)
Lyu C, Da Vela S, Al-Hilaly Y, Marshall K, Thorogate R, Svergun D, Serpell L, Pastore A, Hanger D
RgGuinier 6.3 nm
Dmax 19.8 nm
VolumePorod 211 nm3

SASDLU4 – Tau protein, 2N4R isoform

Microtubule-associated protein tau, 2N4R isoform experimental SAS data
Tau protein, 2N4R isoform Rg histogram
Sample: Microtubule-associated protein tau, 2N4R isoform monomer, 46 kDa Homo sapiens protein
Buffer: phosphate buffered saline, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Oct 8
...Tau35 Fragment has an Increased Propensity to Aggregate Compared to Full-Length Tau Frontiers in Molecular Biosciences 8 (2021)
Lyu C, Da Vela S, Al-Hilaly Y, Marshall K, Thorogate R, Svergun D, Serpell L, Pastore A, Hanger D
RgGuinier 6.7 nm
Dmax 23.5 nm
VolumePorod 254 nm3

SASDV46 – Microtubule-associated protein tau, lysine-rich four-repeat domain 4RD

Isoform Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A) experimental SAS data
Microtubule-associated protein tau, lysine-rich four-repeat domain 4RD Rg histogram
Sample: ...Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A) monomer, 14 kDa Homo sapiens protein
Buffer: 100 mM NaCl, pH: 6.8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Mar 17
...tau repeat domain. Proc Natl Acad Sci U S A 122(15):e2425831122 (2025)
Viola G, Trivellato D, Laitaoja M, Jänis J, Felli IC, D'Onofrio M, Mollica L, Giachin G, Assfalg M
RgGuinier 3.5 nm
Dmax 12.2 nm
VolumePorod 33 nm3

SASDV56 – Microtubule-associated protein tau, lysine-rich four-repeat domain 4RD synthetically linked to Ubiquitin at tau residue C317

Isoform Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A)Polyubiquitin-B experimental SAS data
Microtubule-associated protein tau, lysine-rich four-repeat domain 4RD synthetically linked to Ubiquitin at tau residue C317 Rg histogram
Sample: ...Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A) monomer, 14 kDa Homo sapiens protein
Polyubiquitin-B monomer, 9 kDa Fukomys damarensis protein
Buffer: 100 mM NaCl, pH: 6.8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Mar 17
...tau repeat domain. Proc Natl Acad Sci U S A 122(15):e2425831122 (2025)
Viola G, Trivellato D, Laitaoja M, Jänis J, Felli IC, D'Onofrio M, Mollica L, Giachin G, Assfalg M
RgGuinier 3.3 nm
Dmax 13.3 nm
VolumePorod 41 nm3

SASDV66 – Microtubule-associated protein tau, lysine-rich four-repeat domain 4RD synthetically linked to Ubiquitin at tau residue C353

Isoform Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A)Polyubiquitin-B experimental SAS data
Microtubule-associated protein tau, lysine-rich four-repeat domain 4RD synthetically linked to Ubiquitin at tau residue C353 Rg histogram
Sample: ...Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A) monomer, 14 kDa Homo sapiens protein
Polyubiquitin-B monomer, 9 kDa Fukomys damarensis protein
Buffer: 100 mM NaCl, pH: 6.8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Mar 17
...tau repeat domain. Proc Natl Acad Sci U S A 122(15):e2425831122 (2025)
Viola G, Trivellato D, Laitaoja M, Jänis J, Felli IC, D'Onofrio M, Mollica L, Giachin G, Assfalg M
RgGuinier 3.1 nm
Dmax 12.1 nm
VolumePorod 33 nm3

SASDV76 – Microtubule-associated protein tau, lysine-rich four-repeat domain 4RD synthetically linked to two Ubiquitins at tau residues C311 and C317

Isoform Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A)Polyubiquitin-BPolyubiquitin-B experimental SAS data
Microtubule-associated protein tau, lysine-rich four-repeat domain 4RD synthetically linked to two Ubiquitins at tau residues C311 and C317 Rg histogram
Sample: ...Tau-F of Microtubule-associated protein tau (C291A, K311C, K317C, C322A) monomer, 14 kDa Homo sapiens protein
Polyubiquitin-B monomer, 9 kDa Fukomys damarensis protein
Polyubiquitin-B monomer, 9 kDa Fukomys damarensis protein
Buffer: 100 mM NaCl, pH: 6.8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Mar 17
...tau repeat domain. Proc Natl Acad Sci U S A 122(15):e2425831122 (2025)
Viola G, Trivellato D, Laitaoja M, Jänis J, Felli IC, D'Onofrio M, Mollica L, Giachin G, Assfalg M
RgGuinier 3.3 nm
Dmax 12.2 nm
VolumePorod 59 nm3

SASD2E7 – ...microtubule-associated protein tau dGAE fragment (2N4R residues 297–391)

Microtubule-associated protein tau experimental SAS data
Microtubule-associated protein tau Kratky plot
Sample: Microtubule-associated protein tau monomer, 10 kDa Homo sapiens protein
Buffer: PBS, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2026 Jul 7
Tau preaggregation conformation of trunctated tau proteins
Ondrej Cehlar
RgGuinier 2.7 nm