SASBDB entries for UniProt ID:

SASDSD5 – light-state long-linker LOV-activated diguanylate cyclase

UniProt ID: A0A2S5LZS0 (3-314) Sensor domain-containing diguanylate cyclase
Sensor domain-containing diguanylate cyclase experimental SAS data
Sensor domain-containing diguanylate cyclase Kratky plot
Sample: Sensor domain-containing diguanylate cyclase dimer, 72 kDa Methylotenera sp. protein
Buffer: 10 mM Tris, 50 mM NaCl, 2 mM MgCl2, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2023 May 4
Illuminating the inner workings of a natural protein switch: Blue-light sensing in LOV-activated diguanylate cyclases Science Advances 9(31) (2023)
Vide U, Kasapović D, Fuchs M, Heimböck M, Totaro M, Zenzmaier E, Winkler A
RgGuinier 3.5 nm
Dmax 13.8 nm
VolumePorod 123 nm3

SASDSE5 – SEC-SAXS data of mutant estrogen receptor alpha (S118A), N-terminal domain (NTD) at pH 7.4

UniProt ID: P03372 (1-184) Estrogen receptor (mutant S118A)
Estrogen receptor (mutant S118A) experimental SAS data
Estrogen receptor (mutant S118A) Kratky plot
Sample: Estrogen receptor (mutant S118A) monomer, 20 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 150 mM NaCl, 0.5 mM EDTA, 0.1 mM PMSF, pH: 7.4
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jul 21
The sequence–structure–function relationship of intrinsic ERα disorder Nature (2025)
Du Z, Wang H, Luo S, Yun Z, Wu C, Yang W, Buck M, Zheng W, Hansen A, Kao H, Yang S
RgGuinier 3.2 nm
Dmax 15.0 nm
VolumePorod 71 nm3

SASDSF5 – SEC-SAXS data of mutant estrogen receptor alpha (S118D), N-terminal domain (NTD) at pH 7.4

UniProt ID: P03372 (1-184) Estrogen receptor (mutant S118D)
Estrogen receptor (mutant S118D) experimental SAS data
Estrogen receptor (mutant S118D) Kratky plot
Sample: Estrogen receptor (mutant S118D) monomer, 20 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 150 mM NaCl, 0.5 mM EDTA, 0.1 mM PMSF, pH: 7.4
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jul 21
The sequence–structure–function relationship of intrinsic ERα disorder Nature (2025)
Du Z, Wang H, Luo S, Yun Z, Wu C, Yang W, Buck M, Zheng W, Hansen A, Kao H, Yang S
RgGuinier 3.5 nm
Dmax 16.0 nm
VolumePorod 62 nm3

SASDSG5 – Human MUC2 mucin CysD2 domain

UniProt ID: Q02817 (1781-1892) Mucin-2 (CysD2 domain)
Mucin-2 (CysD2 domain) experimental SAS data
Mucin-2 (CysD2 domain) Kratky plot
Sample: Mucin-2 (CysD2 domain) monomer, 16 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 70 mM NaCl, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Mar 8
The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking. Cell Rep 43(5):114207 (2024)
Recktenwald CV, Karlsson G, Garcia-Bonete MJ, Katona G, Jensen M, Lymer R, Bäckström M, Johansson MEV, Hansson GC, Trillo-Muyo S
RgGuinier 2.5 nm
Dmax 9.3 nm
VolumePorod 31 nm3

SASDSH5 – UDP-glycosyltransferase 202A2 from Tetranychus urticae

UniProt ID: T1KUK4 (1-437) UDP-glycosyltransferase 202A2
UDP-glycosyltransferase 202A2 experimental SAS data
MULTIFOXS model
Sample: UDP-glycosyltransferase 202A2 monomer, 53 kDa Tetranychus urticae protein
Buffer: 20 mM sodium phosphate, 150 mM NaCl, pH: 7.8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jun 17
Structural and functional studies reveal the molecular basis of substrate promiscuity of a glycosyltransferase originating from a major agricultural pest Journal of Biological Chemistry :105421 (2023)
Arriaza R, Abiskaroon B, Patel M, Daneshian L, Kluza A, Snoeck S, Watkins M, Hopkins J, Van Leeuwen T, Grbic M, Grbic V, Borowski T, Chruszcz M
RgGuinier 2.5 nm
Dmax 9.5 nm
VolumePorod 85 nm3

SASDSP5 – SARS-CoV-2 Main Protease H163A Mutant - 0.25 mg/mL

UniProt ID: P0DTD1 (3264-3569) Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant)
Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) experimental SAS data
Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) Kratky plot
Sample: Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) dimer, 67 kDa Severe acute respiratory … protein
Buffer: 25 mM HEPES, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 24
The H163A mutation unravels an oxidized conformation of the SARS-CoV-2 main protease. Nat Commun 14(1):5625 (2023)
Tran N, Dasari S, Barwell SAE, McLeod MJ, Kalyaanamoorthy S, Holyoak T, Ganesan A
RgGuinier 2.4 nm
Dmax 7.8 nm
VolumePorod 63 nm3

SASDSQ5 – SARS-CoV-2 Main Protease H163A Mutant - 0.5 mg/mL

UniProt ID: P0DTD1 (3264-3569) Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant)
Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) experimental SAS data
Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) Kratky plot
Sample: Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) dimer, 67 kDa Severe acute respiratory … protein
Buffer: 25 mM HEPES, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 24
The H163A mutation unravels an oxidized conformation of the SARS-CoV-2 main protease. Nat Commun 14(1):5625 (2023)
Tran N, Dasari S, Barwell SAE, McLeod MJ, Kalyaanamoorthy S, Holyoak T, Ganesan A
RgGuinier 2.5 nm
Dmax 8.2 nm
VolumePorod 74 nm3

SASDSR5 – SARS-CoV-2 Main Protease H163A Mutant - 1.0 mg/mL

UniProt ID: P0DTD1 (3264-3569) Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant)
Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) experimental SAS data
Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) Kratky plot
Sample: Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) dimer, 67 kDa Severe acute respiratory … protein
Buffer: 25 mM HEPES, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 24
The H163A mutation unravels an oxidized conformation of the SARS-CoV-2 main protease. Nat Commun 14(1):5625 (2023)
Tran N, Dasari S, Barwell SAE, McLeod MJ, Kalyaanamoorthy S, Holyoak T, Ganesan A
RgGuinier 2.6 nm
Dmax 8.2 nm
VolumePorod 85 nm3

SASDSS5 – SARS-CoV-2 Main Protease H163A Mutant - 3.0 mg/mL

UniProt ID: P0DTD1 (3264-3569) Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant)
Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) dimer, 67 kDa Severe acute respiratory … protein
Buffer: 25 mM HEPES, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 24
The H163A mutation unravels an oxidized conformation of the SARS-CoV-2 main protease. Nat Commun 14(1):5625 (2023)
Tran N, Dasari S, Barwell SAE, McLeod MJ, Kalyaanamoorthy S, Holyoak T, Ganesan A
RgGuinier 2.6 nm
Dmax 8.5 nm
VolumePorod 102 nm3

SASDST5 – SARS-CoV-2 Main Protease H163A Mutant - 6.3 mg/mL

UniProt ID: P0DTD1 (3264-3569) Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant)
Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) experimental SAS data
Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) Kratky plot
Sample: Replicase polyprotein 1ab, H3426A (3C-like proteinase nsp5 - H163A mutant) dimer, 67 kDa Severe acute respiratory … protein
Buffer: 25 mM HEPES, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2023 Mar 24
The H163A mutation unravels an oxidized conformation of the SARS-CoV-2 main protease. Nat Commun 14(1):5625 (2023)
Tran N, Dasari S, Barwell SAE, McLeod MJ, Kalyaanamoorthy S, Holyoak T, Ganesan A
RgGuinier 2.6 nm
Dmax 7.7 nm
VolumePorod 98 nm3