SASBDB entries for UniProt ID:

SASDXP5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 10 nM Ca2+/CaM

UniProt ID: Q9UQM7 (7-478) Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 7.1 nm

SASDXQ5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 100 nM Ca2+/CaM

UniProt ID: Q9UQM7 (7-478) Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 7.2 nm

SASDXR5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 1000 nM Ca2+/CaM

UniProt ID: Q9UQM7 (7-478) Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 7.6 nm

SASDXS5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 2000 nM Ca2+/CaM

UniProt ID: Q9UQM7 (7-478) Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 7.2 nm

SASDXT5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 5000 nM Ca2+/CaM

UniProt ID: Q9UQM7 (7-478) Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 7.8 nm

SASDXU5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 10000 nM Ca2+/CaM

UniProt ID: Q9UQM7 (7-478) Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 8.0 nm

SASDXV5 – Calcium/calmodulin-dependent protein kinase type II (CaMKII) subunit holoenzyme with Exon 18 as the linker region + 20000 nM Ca2+/CaM

UniProt ID: Q9UQM7 (7-478) Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) experimental SAS data
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase type II subunit alpha (Δ1-6; Q223K; Δ 316-329) dodecamer, 626 kDa Homo sapiens protein
Buffer: 50 mM Tris , 0.2 mM CaCl2, 150 mM KCl, 10 mM MgCl2, 2 mM ATP, pH: 8
Experiment: SAXS data collected at Rigaku/BioSAXS-2000 SAXS, Institute for Applied Life Sciences/Biophysical Characterization on 2024 Dec 18
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation - revision
Bao Nguyen Viet
RgGuinier 10.0 nm

SASDXX5 – SARS-CoV-2 Nucleocapsid protein 0.5 mg/mL

UniProt ID: P0DTC9 (2-419) Nucleoprotein
Nucleoprotein experimental SAS data
Nucleoprotein Kratky plot
Sample: Nucleoprotein dimer, 95 kDa Severe acute respiratory … protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2023 Jul 18
Phosphorylation toggles the SARS-CoV-2 nucleocapsid protein between two membrane-associated condensate states. Nat Commun 16(1):7970 (2025)
Favetta B, Wang H, Cubuk J, Singh A, Barai M, Ramirez C, Zheng H, Gormley AJ, Murthy NS, Dignon G, Soranno A, Shi Z, Schuster BS
RgGuinier 5.8 nm
Dmax 17.1 nm

SASDXY5 – SARS-CoV-2 Nucleocapsid protein 1 mg/mL

UniProt ID: P0DTC9 (2-419) Nucleoprotein
Nucleoprotein experimental SAS data
Nucleoprotein Kratky plot
Sample: Nucleoprotein dimer, 95 kDa Severe acute respiratory … protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2023 Jul 18
Phosphorylation toggles the SARS-CoV-2 nucleocapsid protein between two membrane-associated condensate states. Nat Commun 16(1):7970 (2025)
Favetta B, Wang H, Cubuk J, Singh A, Barai M, Ramirez C, Zheng H, Gormley AJ, Murthy NS, Dignon G, Soranno A, Shi Z, Schuster BS
RgGuinier 5.6 nm
Dmax 18.8 nm

SASDXZ5 – SARS-CoV-2 Nucleocapsid protein 1.5 mg/mL

UniProt ID: P0DTC9 (2-419) Nucleoprotein
Nucleoprotein experimental SAS data
Nucleoprotein Kratky plot
Sample: Nucleoprotein dimer, 95 kDa Severe acute respiratory … protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2023 Jul 18
Phosphorylation toggles the SARS-CoV-2 nucleocapsid protein between two membrane-associated condensate states. Nat Commun 16(1):7970 (2025)
Favetta B, Wang H, Cubuk J, Singh A, Barai M, Ramirez C, Zheng H, Gormley AJ, Murthy NS, Dignon G, Soranno A, Shi Z, Schuster BS
RgGuinier 5.7 nm
Dmax 18.8 nm