SASBDB entries for UniProt ID:

SASDWC6 – RAD51 [F86E, A89E] in complex with BRCA2 truncation containing the second and the third BRC repeats (BRC2-3) at 2 mg/mL

UniProt ID: Q06609 (1-339) DNA repair protein RAD51 homolog 1 (F86E A89E)

UniProt ID: P51587 (1212-1551) Breast cancer type 2 susceptibility protein (BRC repeats 2-3)
DNA repair protein RAD51 homolog 1 (F86E A89E)Breast cancer type 2 susceptibility protein (BRC repeats 2-3) experimental SAS data
DNA repair protein RAD51 homolog 1 (F86E A89E) Breast cancer type 2 susceptibility protein (BRC repeats 2-3) Kratky plot
Sample: DNA repair protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein
Breast cancer type 2 susceptibility protein (BRC repeats 2-3) monomer, 28 kDa Homo sapiens protein
Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jul 1
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 5.7 nm
Dmax 22.0 nm
VolumePorod 167 nm3

SASDWD6 – RAD51 [F86E, A89E] in complex with BRCA2 truncation containing the second, third and fourth BRC repeats (BRC2-4) SEC-SAXS

UniProt ID: P51587 (1212-1551) Breast cancer type 2 susceptibility protein (BRC repeats 2-4)

UniProt ID: Q06609 (1-339) DNA repair protein RAD51 homolog 1 (F86E A89E)
Breast cancer type 2 susceptibility protein (BRC repeats 2-4)DNA repair protein RAD51 homolog 1 (F86E A89E) experimental SAS data
ALPHAFOLD model
Sample: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) monomer, 39 kDa Homo sapiens protein
DNA repair protein RAD51 homolog 1 (F86E A89E) trimer, 111 kDa Homo sapiens protein
Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 100 mM Li₂SO₄, 1 mM DTT, 1% sucrose, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Dec 2
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 6.7 nm
Dmax 28.0 nm
VolumePorod 259 nm3

SASDWE6 – RAD51 [F86E, A89E] in complex with BRCA2 truncation containing the third and fourth BRC repeats (BRC3-4) SEC-SAXS

UniProt ID: P51587 (1421-1551) Breast cancer type 2 susceptibility protein (BRC repeats 3-4)

UniProt ID: Q06609 (1-339) DNA repair protein RAD51 homolog 1 (F86E A89E)
Breast cancer type 2 susceptibility protein (BRC repeats 3-4)DNA repair protein RAD51 homolog 1 (F86E A89E) experimental SAS data
ALPHAFOLD model
Sample: Breast cancer type 2 susceptibility protein (BRC repeats 3-4) monomer, 16 kDa Homo sapiens protein
DNA repair protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein
Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 1 mM DTT, 2% sucrose, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 May 2
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 4.6 nm
Dmax 18.0 nm
VolumePorod 142 nm3

SASDWF6 – RAD51 [F86E, A89E] in complex with BRCA2 truncation containing the third and fourth BRC repeats (BRC3-4) at 0.5 mg/mL

UniProt ID: P51587 (1421-1551) Breast cancer type 2 susceptibility protein (BRC repeats 3-4)

UniProt ID: Q06609 (1-339) DNA repair protein RAD51 homolog 1 (F86E A89E)
Breast cancer type 2 susceptibility protein (BRC repeats 3-4)DNA repair protein RAD51 homolog 1 (F86E A89E) experimental SAS data
Breast cancer type 2 susceptibility protein (BRC repeats 3-4) DNA repair protein RAD51 homolog 1 (F86E A89E) Kratky plot
Sample: Breast cancer type 2 susceptibility protein (BRC repeats 3-4) monomer, 16 kDa Homo sapiens protein
DNA repair protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein
Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jul 1
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 4.6 nm
Dmax 18.5 nm
VolumePorod 175 nm3

SASDWG6 – RAD51 [F86E, A89E] in complex with BRCA2 truncation containing the third and fourth BRC repeats (BRC3-4) at 1 mg/mL

UniProt ID: P51587 (1421-1551) Breast cancer type 2 susceptibility protein (BRC repeats 3-4)

UniProt ID: Q06609 (1-339) DNA repair protein RAD51 homolog 1 (F86E A89E)
Breast cancer type 2 susceptibility protein (BRC repeats 3-4)DNA repair protein RAD51 homolog 1 (F86E A89E) experimental SAS data
Breast cancer type 2 susceptibility protein (BRC repeats 3-4) DNA repair protein RAD51 homolog 1 (F86E A89E) Kratky plot
Sample: Breast cancer type 2 susceptibility protein (BRC repeats 3-4) monomer, 16 kDa Homo sapiens protein
DNA repair protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein
Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jul 1
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 4.5 nm
Dmax 18.0 nm
VolumePorod 140 nm3

SASDWH6 – RAD51 [F86E, A89E] in complex with BRCA2 truncation containing the third and fourth BRC repeats (BRC3-4) at 2 mg/mL

UniProt ID: P51587 (1421-1551) Breast cancer type 2 susceptibility protein (BRC repeats 3-4)

UniProt ID: Q06609 (1-339) DNA repair protein RAD51 homolog 1 (F86E A89E)
Breast cancer type 2 susceptibility protein (BRC repeats 3-4)DNA repair protein RAD51 homolog 1 (F86E A89E) experimental SAS data
Breast cancer type 2 susceptibility protein (BRC repeats 3-4) DNA repair protein RAD51 homolog 1 (F86E A89E) Kratky plot
Sample: Breast cancer type 2 susceptibility protein (BRC repeats 3-4) monomer, 16 kDa Homo sapiens protein
DNA repair protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein
Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jul 1
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 4.6 nm
Dmax 18.3 nm
VolumePorod 148 nm3

SASDWJ6 – RAD51 [F86E, A89E] in complex with BRCA2 truncation containing the first and the second BRC repeats (BRC1-2) SEC-SAXS

UniProt ID: Q06609 (1-339) DNA repair protein RAD51 homolog 1 (F86E A89E)

UniProt ID: P51587 (1002-1246) Breast cancer type 2 susceptibility protein (BRC repeats 1-2)
DNA repair protein RAD51 homolog 1 (F86E A89E)Breast cancer type 2 susceptibility protein (BRC repeats 1-2) experimental SAS data
ALPHAFOLD model
Sample: DNA repair protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein
Breast cancer type 2 susceptibility protein (BRC repeats 1-2) monomer, 28 kDa Homo sapiens protein
Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 1 mM DTT, 2% sucrose, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 May 2
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 5.3 nm
Dmax 21.0 nm
VolumePorod 165 nm3

SASDWK6 – RAD51 [F86E, A89E] in complex with BRCA2 truncation containing the first and the second BRC repeats (BRC1-2) at 0.5 mg/mL

UniProt ID: Q06609 (1-339) DNA repair protein RAD51 homolog 1 (F86E A89E)

UniProt ID: P51587 (1002-1246) Breast cancer type 2 susceptibility protein (BRC repeats 1-2)
DNA repair protein RAD51 homolog 1 (F86E A89E)Breast cancer type 2 susceptibility protein (BRC repeats 1-2) experimental SAS data
DNA repair protein RAD51 homolog 1 (F86E A89E) Breast cancer type 2 susceptibility protein (BRC repeats 1-2) Kratky plot
Sample: DNA repair protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein
Breast cancer type 2 susceptibility protein (BRC repeats 1-2) monomer, 28 kDa Homo sapiens protein
Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jul 1
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 5.7 nm
Dmax 24.0 nm
VolumePorod 249 nm3

SASDWL6 – RAD51 [F86E, A89E] in complex with BRCA2 truncation containing the first and the second BRC repeats (BRC1-2) at 1 mg/mL

UniProt ID: Q06609 (1-339) DNA repair protein RAD51 homolog 1 (F86E A89E)

UniProt ID: P51587 (1002-1246) Breast cancer type 2 susceptibility protein (BRC repeats 1-2)
DNA repair protein RAD51 homolog 1 (F86E A89E)Breast cancer type 2 susceptibility protein (BRC repeats 1-2) experimental SAS data
DNA repair protein RAD51 homolog 1 (F86E A89E) Breast cancer type 2 susceptibility protein (BRC repeats 1-2) Kratky plot
Sample: DNA repair protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein
Breast cancer type 2 susceptibility protein (BRC repeats 1-2) monomer, 28 kDa Homo sapiens protein
Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jul 1
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 5.5 nm
Dmax 21.0 nm
VolumePorod 208 nm3

SASDWM6 – RAD51 [F86E, A89E] in complex with BRCA2 truncation containing the first and the second BRC repeats (BRC1-2) at 2 mg/mL

UniProt ID: Q06609 (1-339) DNA repair protein RAD51 homolog 1 (F86E A89E)

UniProt ID: P51587 (1002-1246) Breast cancer type 2 susceptibility protein (BRC repeats 1-2)
DNA repair protein RAD51 homolog 1 (F86E A89E)Breast cancer type 2 susceptibility protein (BRC repeats 1-2) experimental SAS data
DNA repair protein RAD51 homolog 1 (F86E A89E) Breast cancer type 2 susceptibility protein (BRC repeats 1-2) Kratky plot
Sample: DNA repair protein RAD51 homolog 1 (F86E A89E) dimer, 74 kDa Homo sapiens protein
Breast cancer type 2 susceptibility protein (BRC repeats 1-2) monomer, 28 kDa Homo sapiens protein
Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jul 1
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 5.5 nm
Dmax 23.0 nm
VolumePorod 191 nm3