SASBDB entries for UniProt ID:

SASDTJ2 – Low complexity domain of hnRNPA1 (Heterogeneous nuclear ribonucleoprotein A1)

UniProt ID: P09651-2 (186-320) Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1
Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 experimental SAS data
Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 Kratky plot
Sample: Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 monomer, 13 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM DTT, pH: 7
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Nov 19
Design of intrinsically disordered protein variants with diverse structural properties Science Advances 10(35) (2024)
Pesce F, Bremer A, Tesei G, Hopkins J, Grace C, Mittag T, Lindorff-Larsen K
RgGuinier 2.4 nm
Dmax 8.0 nm
VolumePorod 19 nm3

SASDT33 – Teneurin-3 A1B1 isoform in 2 mM calcium - 0.31 mg/mL

UniProt ID: Q9WTS6-1 (343-2715) Isoform A1B1 of Teneurin-3
Isoform A1B1 of Teneurin-3 experimental SAS data
Isoform A1B1 of Teneurin-3 Kratky plot
Sample: Isoform A1B1 of Teneurin-3 dimer, 545 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.8
Experiment: SAXS data collected at BM29, ESRF on 2022 Sep 10
Alternative splicing controls teneurin-3 compact dimer formation for neuronal recognition Nature Communications 15(1) (2024)
Gogou C, Beugelink J, Frias C, Kresik L, Jaroszynska N, Drescher U, Janssen B, Hindges R, Meijer D
RgGuinier 7.9 nm
Dmax 33.0 nm
VolumePorod 1129 nm3

SASDT95 – Trypanosoma brucei gambiense invariant surface glycoprotein 75 (ISG75)

UniProt ID: Q1WK95 (29-462) ISG75
ISG75 experimental SAS data
BILBOMD model
Sample: ISG75 monomer, 50 kDa Trypanosoma brucei gambiense protein
Buffer: 20 mM HEPES, 150 mM NaCl, 3% glycerol, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2020 Nov 25
Beyond the VSG Layer: Exploring the Role of Intrinsic Disorder in the Invariant Surface Glycoproteins of African Trypanosomes. PLoS Pathog 20(4):e1012186 (2024)
Sülzen H, Volkov AN, Geens R, Zahedifard F, Stijlemans B, Zoltner M, Magez S, Sterckx YG, Zoll S
RgGuinier 3.2 nm
Dmax 11.1 nm
VolumePorod 85 nm3

SASDUN9 – Wild-type Importin Beta Binding domain (IBB) from importin subunit alpha-1 in 6 M Urea

UniProt ID: J3QLL0 (2-73) Importin subunit alpha-1
Importin subunit alpha-1 experimental SAS data
Importin subunit alpha-1 Kratky plot
Sample: Importin subunit alpha-1 monomer, 9 kDa Homo sapiens protein
Buffer: phosphate buffered saline containing 6 M urea, 0.3 M KCl, 5 mM DTT, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Jun 29
A genetically encoded anomalous SAXS ruler to probe the dimensions of intrinsically disordered proteins. Proc Natl Acad Sci U S A 121(50):e2415220121 (2024)
Yu M, Gruzinov AY, Ruan H, Scheidt T, Chowdhury A, Giofrè S, Mohammed ASA, Caria J, Sauter PF, Svergun DI, Lemke EA
RgGuinier 2.7 nm
Dmax 11.9 nm
VolumePorod 23 nm3

SASDVG2 – Staphylococcal extracellular adherence protein (Eap) bound to human cathepsin-G

UniProt ID: Q99QS1 (32-478) Protein map

UniProt ID: P08311 (22-245) Cathepsin G
Protein mapCathepsin G experimental SAS data
MULTIFOXS model
Sample: Protein map monomer, 50 kDa Staphylococcus aureus (strain … protein
Cathepsin G tetramer, 101 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 140 mM NaCl, pH: 7.4
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Jun 3
S. aureus Eap is a polyvalent inhibitor of neutrophil serine proteases. J Biol Chem 300(9):107627 (2024)
Mishra N, Gido CD, Herdendorf TJ, Hammel M, Hura GL, Fu ZQ, Geisbrecht BV
RgGuinier 5.0 nm
Dmax 20.2 nm
VolumePorod 166 nm3

SASDV37 – Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4) point mutant L28D

UniProt ID: Q8N4Q1 (1-142) Mitochondrial intermembrane space import and assembly protein 40
Mitochondrial intermembrane space import and assembly protein 40 experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 monomer, 16 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Oct 26
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 2.8 nm
Dmax 9.2 nm
VolumePorod 52 nm3

SASDV29 – Complex of human DNA methyltransferase 3 beta DNMT3B (215-853) and DNA methyltransferase 3-like DNMT3L (178-379)

UniProt ID: Q9UBC3 (215-853) DNA methyltransferase 3 beta (215-853)

UniProt ID: Q9UJW3 (178-379) DNA methyltransferase 3-like (178-379)
DNA methyltransferase 3 beta (215-853)DNA methyltransferase 3-like (178-379) experimental SAS data
GASBOR model
Sample: DNA methyltransferase 3 beta (215-853) dimer, 145 kDa Homo sapiens protein
DNA methyltransferase 3-like (178-379) dimer, 47 kDa Homo sapiens protein
Buffer: 20 mM Tris, 300 mM NaCl, 1 mM TCEP, 5% glycerol, pH: 8
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2021 Apr 16
Histone modification-driven structural remodeling unleashes DNMT3B in DNA methylation. Sci Adv 11(13):eadu8116 (2025)
Cho CC, Huang HH, Jiang BC, Yang WZ, Chen YN, Yuan HS
RgGuinier 5.2 nm
Dmax 21.2 nm
VolumePorod 271263 nm3

SASDB56 – Deglycosylated myelin-associated glycoprotein full extracellular domain (Ig 1-5) I473E mutant

UniProt ID: P20917 (20-508) Myelin-associated glycoprotein (20-508; I473E mutant)
Myelin-associated glycoprotein (20-508; I473E mutant) experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Myelin-associated glycoprotein (20-508; I473E mutant) monomer, 54 kDa Mus musculus protein
Buffer: 20 mM HEPES 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2014 Sep 11
Structural basis of myelin-associated glycoprotein adhesion and signalling. Nat Commun 7:13584 (2016)
Pronker MF, Lemstra S, Snijder J, Heck AJ, Thies-Weesie DM, Pasterkamp RJ, Janssen BJ
RgGuinier 6.0 nm
Dmax 21.2 nm
VolumePorod 100 nm3

SASDCN4 – Collagenase ColH s2as2bs3 at pCa 3

UniProt ID: Q46085 (718-1021) Collagenase ColH segement s2as2bs3
Collagenase ColH segement s2as2bs3 experimental SAS data
DAMMIF model
Sample: Collagenase ColH segement s2as2bs3 monomer, 34 kDa Hathewaya histolytica protein
Buffer: 10mM HEPES 100mM NaCl 0.2mM EGTA, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2016 Oct 12
Ca2+ - Induced Structural Change of Multi-Domain Collagen Binding Segments of Collagenases ColG and ColH from Hathewaya histolytica University of Arkansas Dissertation - (2018)
Christopher E Ruth
RgGuinier 3.3 nm
Dmax 13.6 nm
VolumePorod 35 nm3

SASDDQ8 – The complex formed between the class II apurinic/apyrimidinic-endonuclease/3'-5' exonuclease III (XthA) bound to the BRCT domain from Mycobacterium tuberculosis DNA ligase

UniProt ID: A0A0T9L251 (None-None) Probable exodeoxyribonuclease III protein XthA

UniProt ID: P9WNV1 (601-691) M. tb. LigA BRCT domain
Probable exodeoxyribonuclease III protein XthAM. tb. LigA BRCT domain experimental SAS data
DAMFILT model
Sample: Probable exodeoxyribonuclease III protein XthA monomer, 33 kDa Mycobacterium tuberculosis protein
M. tb. LigA BRCT domain monomer, 15 kDa Mycobacterium tuberculosis protein
Buffer: 50 mM Tris-HCl 500 mM NaCl 5mM β-mercaptoethanol, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2018 Mar 9
M. tuberculosis class II apurinic/ apyrimidinic-endonuclease/3'-5' exonuclease (XthA) engages with NAD+-dependent DNA ligase A (LigA) to counter futile cleavage and ligation cycles in base excision repair. Nucleic Acids Res (2020)
Khanam T, Afsar M, Shukla A, Alam F, Kumar S, Soyar H, Dolma K, Pasupuleti M, Srivastava KK, Ampapathi RS, Ramachandran R
RgGuinier 3.7 nm
Dmax 18.5 nm
VolumePorod 112 nm3