Browse by DISSEMINATION: Published

SASDXB9 – O’Nyong-Nyong virus (ONNV) nsP4 full length wild type

RNA-directed RNA polymerase nsP4 experimental SAS data
RNA-directed RNA polymerase nsP4 Kratky plot
Sample: RNA-directed RNA polymerase nsP4 monomer, 68 kDa O'nyong-nyong virus protein
Buffer: 25 mM HEPES, 1 mM TCEP, 5% glycerol and 500 mM NaCl., pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, Pennsylvania State University on 2023 Jun 8
A fold switch regulates conformation of an alphavirus RNA-dependent RNA polymerase. Nucleic Acids Res 54(2) (2026)
Arnold JJ, Braet SM, Vieira LC, Moustafa IM, Gohara DW, Fecko JA, Su YN, Jain A, Aponte-Diaz D, Wilke CO, Anand GS, Yennawar NH, Cameron CE
RgGuinier 3.6 nm

SASDXC9 – O'Nyong Nyong virus C-terminus-50residues-nsP3-nsP4 fusion protein

50-residue-C-terminus-nsP3 fused with RNA-directed RNA polymerase nsP4 experimental SAS data
50-residue-C-terminus-nsP3 fused with RNA-directed RNA polymerase nsP4 Kratky plot
Sample: 50-residue-C-terminus-nsP3 fused with RNA-directed RNA polymerase nsP4 tetramer, 318 kDa O'nyong nyong virus protein
Buffer: 25 mM HEPES 5% glycerol, 1 mM TCEP, 500 mM NaCl., pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, Pennsylvania State University on 2025 Aug 14
A fold switch regulates conformation of an alphavirus RNA-dependent RNA polymerase. Nucleic Acids Res 54(2) (2026)
Arnold JJ, Braet SM, Vieira LC, Moustafa IM, Gohara DW, Fecko JA, Su YN, Jain A, Aponte-Diaz D, Wilke CO, Anand GS, Yennawar NH, Cameron CE
RgGuinier 5.2 nm

SASDWP9 – Ratiometric matryoshka biosensor for Fe2+ – MDtxRGA_G149

Ratiometric matryoshka biosensor for Fe2+ experimental SAS data
ALPHAFOLD model
Sample: Ratiometric matryoshka biosensor for Fe2+ monomer, 84 kDa synthetic construct protein
Buffer: 20 mM MOPS, 250 mM KCl,, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Nov 15
A Novel Biosensor for Ferrous Iron Developed via CoBiSe: A Computational Method for Rapid Biosensor Design ACS Sensors (2026)
Papadopoulos A, Anlauf M, Reiners J, Paik S, Krüger A, Lückel B, Bott M, Drepper T, Frunzke J, Gohlke H, Weidtkamp-Peters S, Smits S, Gertzen C
RgGuinier 3.6 nm
Dmax 12.4 nm
VolumePorod 118 nm3

SASDWY9 – Small EDRK-rich factor 1 protein (SERF1a) at pH 6

Isoform Short of Small EDRK-rich factor 1 experimental SAS data
OTHER model
Sample: Isoform Short of Small EDRK-rich factor 1 monomer, 7 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 20 mM NaCl, pH: 6
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 Mar 9
pH Sensitivity of the SERF1a Conformational Ensemble ACS Omega (2026)
Huang S, Shih O, Jeng U, Chang C, Lin J, Malliavin T
RgGuinier 2.4 nm
Dmax 10.3 nm
VolumePorod 10 nm3

SASDWZ9 – Small EDRK-rich factor 1 protein (SERF1a) at pH 6.8

Isoform Short of Small EDRK-rich factor 1 experimental SAS data
OTHER model
Sample: Isoform Short of Small EDRK-rich factor 1 monomer, 7 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 20 mM NaCl, pH: 6.8
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 Mar 9
pH Sensitivity of the SERF1a Conformational Ensemble ACS Omega (2026)
Huang S, Shih O, Jeng U, Chang C, Lin J, Malliavin T
RgGuinier 2.5 nm
Dmax 8.8 nm
VolumePorod 11 nm3

SASDWS6 – Frataxin bound to tailored nanobody 28F6

Frataxin, mitochondrialNanobody 28F6 experimental SAS data
ALPHAFOLD model
Sample: Frataxin, mitochondrial monomer, 14 kDa Homo sapiens protein
Nanobody 28F6 monomer, 15 kDa synthetic construct protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Sep 18
Nanobodies as tools for studying human frataxin biology. Commun Biol (2026)
Pignataro MF, Fernández NB, Garay-Alvarez A, Pavan MF, Molina R, Muñoz IG, Grossi J, Noguera M, Vila A, García AE, Gentili HG, Rodríguez NA, Aran M, Parreño V, Bok M, Hermoso JA, Ibañez LI, Santos J
RgGuinier 2.2 nm
Dmax 7.4 nm
VolumePorod 36 nm3

SASDWT6 – Frataxin bound to tailored nanobody 16C10

Frataxin, mitochondrialNanobody 16C10 experimental SAS data
COOT model
Sample: Frataxin, mitochondrial monomer, 14 kDa Homo sapiens protein
Nanobody 16C10 monomer, 15 kDa synthetic construct protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Sep 18
Nanobodies as tools for studying human frataxin biology. Commun Biol (2026)
Pignataro MF, Fernández NB, Garay-Alvarez A, Pavan MF, Molina R, Muñoz IG, Grossi J, Noguera M, Vila A, García AE, Gentili HG, Rodríguez NA, Aran M, Parreño V, Bok M, Hermoso JA, Ibañez LI, Santos J
RgGuinier 2.4 nm
Dmax 8.0 nm
VolumePorod 37 nm3

SASDUF9 – Mononuclear iron bound form of pigeon ISCA1 under 180 mT magnetic field for 60min

Pigeon iron-sulfur cluster assembly 1 homolog, mitochondrial experimental SAS data
Pigeon iron-sulfur cluster assembly 1 homolog, mitochondrial Kratky plot
Sample: Pigeon iron-sulfur cluster assembly 1 homolog, mitochondrial, 15 kDa Columba livia protein
Buffer: 20 mM Tris-HCl, 0.15 M NaCl, 10 mM 3-mercapto-1,2-propanediol, pH: 8
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2021 Jun 8
A hidden property of the iron-sulfur protein in the mononuclear iron-bound state: species-dependent structural ordering induced by magnetic fields. FEBS J (2025)
Arai S, Soga S, Hirai M, Kobayashi R, Masai H, Kimura K, Maeda K, Nagashima H
RgGuinier 2.8 nm
Dmax 10.5 nm
VolumePorod 85 nm3

SASDUG9 – Mononuclear iron bound form of human ISCA1 under geomagnetic field

Human Iron-sulfur cluster assembly 1 homolog, mitochondrial experimental SAS data
DAMMIN model
Sample: Human Iron-sulfur cluster assembly 1 homolog, mitochondrial, 14 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 0.15 M NaCl, 10 mM 3-mercapto-1,2-propanediol, pH: 8
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2024 Apr 29
A hidden property of the iron-sulfur protein in the mononuclear iron-bound state: species-dependent structural ordering induced by magnetic fields. FEBS J (2025)
Arai S, Soga S, Hirai M, Kobayashi R, Masai H, Kimura K, Maeda K, Nagashima H
RgGuinier 4.1 nm
Dmax 16.4 nm
VolumePorod 105 nm3

SASDUH9 – Mononuclear iron bound form of human ISCA1 under 180 mT magnetic field for 1 min

Human Iron-sulfur cluster assembly 1 homolog, mitochondrial experimental SAS data
Human Iron-sulfur cluster assembly 1 homolog, mitochondrial Kratky plot
Sample: Human Iron-sulfur cluster assembly 1 homolog, mitochondrial, 14 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 0.15 M NaCl, 10 mM 3-mercapto-1,2-propanediol, pH: 8
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2023 Dec 1
A hidden property of the iron-sulfur protein in the mononuclear iron-bound state: species-dependent structural ordering induced by magnetic fields. FEBS J (2025)
Arai S, Soga S, Hirai M, Kobayashi R, Masai H, Kimura K, Maeda K, Nagashima H
RgGuinier 2.9 nm
Dmax 8.8 nm
VolumePorod 55 nm3