Browse by MODEL: Ab initio only

SASDHM9 – Truncated HERV-K Rec response element (RcRE) RNA

Truncated HERV-K Rec response element experimental SAS data
DAMFILT model
Sample: Truncated HERV-K Rec response element monomer, 102 kDa Homo sapiens RNA
Buffer: 10mM Tris-HCl, 100mM KCl, and 0.5mM MgCl₂, pH: 8
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Jul 17
Structural Mimicry Drives HIV-1 Rev-Mediated HERV-K Expression Journal of Molecular Biology 432(24):166711 (2020)
O'Carroll I, Fan L, Kroupa T, McShane E, Theodore C, Yates E, Kondrup B, Ding J, Martin T, Rein A, Wang Y
RgGuinier 6.1 nm
Dmax 21.8 nm
VolumePorod 322 nm3

SASDHN9 – TrΔSLIII HERV-K Rec response element (RcRE) RNA

TrΔSLIII HERV-K Rec response element experimental SAS data
DAMFILT model
Sample: TrΔSLIII HERV-K Rec response element monomer, 88 kDa Homo sapiens RNA
Buffer: 10mM Tris-HCl, 100mM KCl, and 0.5mM MgCl₂, pH: 8
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Dec 7
Structural Mimicry Drives HIV-1 Rev-Mediated HERV-K Expression Journal of Molecular Biology 432(24):166711 (2020)
O'Carroll I, Fan L, Kroupa T, McShane E, Theodore C, Yates E, Kondrup B, Ding J, Martin T, Rein A, Wang Y
RgGuinier 5.3 nm
Dmax 19.2 nm
VolumePorod 226 nm3

SASDHP9 – TrΔSLIIab HERV-K Rec response element (RcRE) RNA

TrΔSLIIab HERV-K Rec response element experimental SAS data
DAMFILT model
Sample: TrΔSLIIab HERV-K Rec response element monomer, 86 kDa Homo sapiens RNA
Buffer: 10mM Tris-HCl, 100mM KCl, and 0.5mM MgCl₂, pH: 8
Experiment: SAXS data collected at 12-ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Feb 21
Structural Mimicry Drives HIV-1 Rev-Mediated HERV-K Expression Journal of Molecular Biology 432(24):166711 (2020)
O'Carroll I, Fan L, Kroupa T, McShane E, Theodore C, Yates E, Kondrup B, Ding J, Martin T, Rein A, Wang Y
RgGuinier 5.0 nm
Dmax 18.4 nm
VolumePorod 201 nm3

SASDJB9 – LIM/homeobox protein Lhx3 homeodomain (Lhx3-HD): HD3

LIM/homeobox protein Lhx3 experimental SAS data
MONSA model
Sample: LIM/homeobox protein Lhx3 monomer, 10 kDa Mus musculus protein
Buffer: 20 mM sodium phosphate monobasic/dibasic, 100 mM NaCl, 1 mM DTT, pH: 7.4
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2018 Nov 2
Contrasting DNA-binding behaviour by ISL1 and LHX3 underpins differential gene targeting in neuronal cell specification Journal of Structural Biology: X :100043 (2020)
Smith N, Wilkinson-White L, Kwan A, Trewhella J, Matthews J
RgGuinier 2.1 nm
Dmax 7.0 nm
VolumePorod 18 nm3

SASDJC9 – Insulin gene enhancer protein Isl-1 LIM-interaction domain (Isl1-LID) fused to the LIM/homeobox protein Lhx3 LIM-homeodomain (Lhx3-LIMHD): LLHD3

LIM/homeobox protein Lhx3Insulin gene enhancer protein ISL-1 experimental SAS data
MONSA model
Sample: LIM/homeobox protein Lhx3 monomer, 23 kDa Mus musculus protein
Insulin gene enhancer protein ISL-1 monomer, 4 kDa Mus musculus protein
Buffer: 20 mM sodium phosphate monobasic/dibasic, 100 mM NaCl, 1 mM DTT, pH: 7.4
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2018 Nov 2
Contrasting DNA-binding behaviour by ISL1 and LHX3 underpins differential gene targeting in neuronal cell specification Journal of Structural Biology: X :100043 (2020)
Smith N, Wilkinson-White L, Kwan A, Trewhella J, Matthews J
RgGuinier 3.3 nm
Dmax 12.0 nm
VolumePorod 39 nm3

SASDJD9 – Insulin gene enhancer protein Isl-1 homeodomain (Isl1-HD) fused to the LIM/homeobox protein Lhx3 homeodomain (Lhx3-HD): 2HD

Insulin gene enhancer protein ISL-1LIM/homeobox protein Lhx3 experimental SAS data
MONSA model
Sample: Insulin gene enhancer protein ISL-1 monomer, 12 kDa Mus musculus protein
LIM/homeobox protein Lhx3 monomer, 9 kDa Mus musculus protein
Buffer: 20 mM sodium phosphate monobasic/dibasic, 100 mM NaCl, 1 mM DTT, pH: 7.4
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2018 Nov 2
Contrasting DNA-binding behaviour by ISL1 and LHX3 underpins differential gene targeting in neuronal cell specification Journal of Structural Biology: X :100043 (2020)
Smith N, Wilkinson-White L, Kwan A, Trewhella J, Matthews J
RgGuinier 3.4 nm
Dmax 12.7 nm
VolumePorod 40 nm3

SASDJE9 – Insulin gene enhancer protein Isl-1 homeodomain/LIM-interaction domain (Isl1-HDLID) fused to the LIM/homeobox protein Lhx3 LIM-homeodomain (Lhx3-LIMHD): 2HDLL

Insulin gene enhancer protein ISL-1LIM/homeobox protein Lhx3 experimental SAS data
MONSA model
Sample: Insulin gene enhancer protein ISL-1 monomer, 14 kDa Mus musculus protein
LIM/homeobox protein Lhx3 monomer, 23 kDa Mus musculus protein
Buffer: 20 mM sodium phosphate monobasic/dibasic, 100 mM NaCl, 1 mM DTT, pH: 7.4
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2018 Nov 2
Contrasting DNA-binding behaviour by ISL1 and LHX3 underpins differential gene targeting in neuronal cell specification Journal of Structural Biology: X :100043 (2020)
Smith N, Wilkinson-White L, Kwan A, Trewhella J, Matthews J
RgGuinier 3.4 nm
Dmax 13.0 nm
VolumePorod 76 nm3

SASDJF9 – M100 DNA oligonucleotide bound to the LIM/homeobox protein Lhx3 homeodomain (Lhx3-HD): M100 + HD3

M100 oligonucleotideLIM/homeobox protein Lhx3 experimental SAS data
MONSA model
Sample: M100 oligonucleotide monomer, 12 kDa DNA
LIM/homeobox protein Lhx3 monomer, 10 kDa Mus musculus protein
Buffer: 20 mM sodium phosphate monobasic/dibasic, 100 mM NaCl, 1 mM DTT, pH: 7.4
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2018 Nov 2
Contrasting DNA-binding behaviour by ISL1 and LHX3 underpins differential gene targeting in neuronal cell specification Journal of Structural Biology: X :100043 (2020)
Smith N, Wilkinson-White L, Kwan A, Trewhella J, Matthews J
RgGuinier 2.1 nm
Dmax 7.0 nm
VolumePorod 27 nm3

SASDJG9 – M100 DNA oligonucleotide bound to the protein fusion of Insulin gene enhancer protein Isl-1 LIM-interaction domain (Isl1-LID) and LIM/homeobox protein Lhx3 LIM-homeodomain (Lhx3-LIMHD): M100 + LLHD3

M100 oligonucleotideLIM/homeobox protein Lhx3Insulin gene enhancer protein ISL-1 experimental SAS data
MONSA model
Sample: M100 oligonucleotide monomer, 12 kDa DNA
LIM/homeobox protein Lhx3 monomer, 23 kDa Mus musculus protein
Insulin gene enhancer protein ISL-1 monomer, 4 kDa Mus musculus protein
Buffer: 20 mM sodium phosphate monobasic/dibasic, 100 mM NaCl, 1 mM DTT, pH: 7.4
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2018 Nov 2
Contrasting DNA-binding behaviour by ISL1 and LHX3 underpins differential gene targeting in neuronal cell specification Journal of Structural Biology: X :100043 (2020)
Smith N, Wilkinson-White L, Kwan A, Trewhella J, Matthews J
RgGuinier 3.6 nm
Dmax 13.0 nm
VolumePorod 49 nm3

SASDJH9 – M100 DNA oligonucleotide bound to the protein fusion of Insulin gene enhancer protein Isl-1 homeodomain (Isl1-HD) and LIM/homeobox protein Lhx3 homeodomain (Lhx3-HD): M100 + 2HD

M100 oligonucleotideInsulin gene enhancer protein ISL-1LIM/homeobox protein Lhx3 experimental SAS data
MONSA model
Sample: M100 oligonucleotide monomer, 12 kDa DNA
Insulin gene enhancer protein ISL-1 monomer, 12 kDa Mus musculus protein
LIM/homeobox protein Lhx3 monomer, 9 kDa Mus musculus protein
Buffer: 20 mM sodium phosphate monobasic/dibasic, 100 mM NaCl, 1 mM DTT, pH: 7.4
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2018 Nov 2
Contrasting DNA-binding behaviour by ISL1 and LHX3 underpins differential gene targeting in neuronal cell specification Journal of Structural Biology: X :100043 (2020)
Smith N, Wilkinson-White L, Kwan A, Trewhella J, Matthews J
RgGuinier 2.4 nm
Dmax 7.5 nm
VolumePorod 41 nm3