Browse by MODEL: Ab initio only

SASDT72 – GAGE6 60bp dsDNA oligonucleotide

GAGE6 60bp dsDNA oligo experimental SAS data
DAMMIN model
Sample: GAGE6 60bp dsDNA oligo monomer, 37 kDa Homo sapiens DNA
Buffer: 150 mM KCl, 20 mM HEPES, 5% glycerol, 5 mM MgCl2, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2023 Mar 14
Probing the statistics of sequence-dependent DNA conformations in solution using SAXS
Heidar Koning
RgGuinier 4.7 nm
Dmax 20.7 nm
VolumePorod 101 nm3

SASDVC9 – 7SK small nuclear RNA State A Low Magnesium Concentration Ensemble

RNA component of 7SK nuclear ribonucleoprotein experimental SAS data
DAMMIN model
Sample: RNA component of 7SK nuclear ribonucleoprotein monomer, 107 kDa Homo sapiens RNA
Buffer: 10 mM Bis-Tris, 100 mM NaCl, 15 mM KCl, 5% Glycerol, 3 mM MgCl2, pH: 5.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jun 21
Solution Structure Determination and Biophysical Studies of 7SK RNP and 7SL SRP RNAs. RNA (2025)
D'Souza MH, Pereira HS, Tersteeg S, Vasudeva G, Siddiqui MQ, Agunlejika T, Kerr L, Girodat D, Patel T
RgGuinier 8.0 nm
Dmax 23.2 nm
VolumePorod 600 nm3

SASDVD9 – 7SK small nuclear RNA State B Low Magnesium Concentration Ensemble

RNA component of 7SK nuclear ribonucleoprotein experimental SAS data
DAMMIN model
Sample: RNA component of 7SK nuclear ribonucleoprotein monomer, 107 kDa Homo sapiens RNA
Buffer: 10 mM Bis-Tris, 100 mM NaCl, 15 mM KCl, 5% Glycerol, 3 mM MgCl2, pH: 5.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jun 21
Solution Structure Determination and Biophysical Studies of 7SK RNP and 7SL SRP RNAs. RNA (2025)
D'Souza MH, Pereira HS, Tersteeg S, Vasudeva G, Siddiqui MQ, Agunlejika T, Kerr L, Girodat D, Patel T
RgGuinier 7.9 nm
Dmax 24.1 nm
VolumePorod 290 nm3

SASDVE9 – 7SL Signal Recognition Particle

7SL Signal Reocgnition Particle RNA experimental SAS data
DAMMIN model
Sample: 7SL Signal Reocgnition Particle RNA monomer, 98 kDa Homo sapiens RNA
Buffer: 10 mM Bis-Tris, 100 mM NaCl, 15 mM KCl, 5% Glycerol, 3 mM MgCl2, pH: 5.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jun 21
Solution Structure Determination and Biophysical Studies of 7SK RNP and 7SL SRP RNAs. RNA (2025)
D'Souza MH, Pereira HS, Tersteeg S, Vasudeva G, Siddiqui MQ, Agunlejika T, Kerr L, Girodat D, Patel T
RgGuinier 6.7 nm
Dmax 21.7 nm
VolumePorod 300 nm3

SASDRX6 – lantibiotic dehydratase MadB (apo)

Thiopeptide-type bacteriocin biosynthesis domain containing protein experimental SAS data
GASBOR model
Sample: Thiopeptide-type bacteriocin biosynthesis domain containing protein dimer, 250 kDa Clostridium sp. Maddingley … protein
Buffer: 50 mM HEPES, 200 mM NaCl, 1 % (v/v) Glycerol, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Jun 26
Structural insights into the substrate binding mechanism of the class I dehydratase MadB Communications Biology 8(1) (2025)
Knospe C, Ortiz J, Reiners J, Kedrov A, Gertzen C, Smits S, Schmitt L
RgGuinier 4.5 nm
Dmax 13.6 nm
VolumePorod 440 nm3

SASDRY6 – lantibiotic dehydratase MadB bound to truncated maddinglicin with a full leader peptide (Leader3)

Thiopeptide-type bacteriocin biosynthesis domain containing proteinLantibiotic, gallidermin/nisin family experimental SAS data
GASBOR model
Sample: Thiopeptide-type bacteriocin biosynthesis domain containing protein dimer, 250 kDa Clostridium sp. Maddingley … protein
Lantibiotic, gallidermin/nisin family monomer, 3 kDa Clostridium sp. Maddingley … protein
Buffer: 50 mM HEPES, 200 mM NaCl, 1 % (v/v) Glycerol, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2020 Dec 3
Structural insights into the substrate binding mechanism of the class I dehydratase MadB Communications Biology 8(1) (2025)
Knospe C, Ortiz J, Reiners J, Kedrov A, Gertzen C, Smits S, Schmitt L
RgGuinier 4.5 nm
Dmax 13.8 nm
VolumePorod 445 nm3

SASDV84 – SH-01 in complex with Fab 3E12

SH-01Fab 3E12 experimental SAS data
DAMMIN model
Sample: SH-01 monomer, 41 kDa protein
Fab 3E12 monomer, 50 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 3% glycerol, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Jun 15
A SELECTIVE ALTERNATIVE PATHWAY COMPLEMENT INHIBITOR FOR TREATMENT OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA
Hagen Sülzen
RgGuinier 3.8 nm
Dmax 14.0 nm
VolumePorod 124 nm3

SASDVV2 – Fas-activated serine/threonine kinase/phosphoprotein FASTK (76-549)

Fas-activated serine/threonine kinase (amino acids 76-549) experimental SAS data
Sample: Fas-activated serine/threonine kinase (amino acids 76-549) monomer, 53 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl, 5% (v/v) Glycerol, 200 mM Ammonium Sulphate, 50 mM NaCl, 0.5 mM TCEP, 10 mM Glutamic acid, 10 mM Arginine;, pH: 8.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2020 Jan 31
Human FASTK preferentially binds single-stranded and G-rich RNA. FEBS J (2025)
Dawidziak DM, Dzadz DA, Kuska MI, Kanavalli M, Klimecka MM, Merski M, Bandyra KJ, Górna MW
RgGuinier 3.6 nm
Dmax 16.3 nm
VolumePorod 96 nm3

SASDVW2 – Fas-activated serine/threonine kinase/phosphoprotein FASTK (169-549)

Fas-activated serine/threonine kinase (amino acids 169-549) experimental SAS data
Sample: Fas-activated serine/threonine kinase (amino acids 169-549) monomer, 43 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl, 5% (v/v) Glycerol, 200 mM Ammonium Sulphate, 50 mM NaCl, 0.5 mM TCEP, 10 mM Glutamic acid, 10 mM Arginine;, pH: 8.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2020 Jan 31
Human FASTK preferentially binds single-stranded and G-rich RNA. FEBS J (2025)
Dawidziak DM, Dzadz DA, Kuska MI, Kanavalli M, Klimecka MM, Merski M, Bandyra KJ, Górna MW
RgGuinier 2.8 nm
Dmax 12.0 nm
VolumePorod 67 nm3

SASDU59 – BC120 RNA

BC120 RNA monomer experimental SAS data
DAMMIN model
Sample: BC120 RNA monomer monomer, 39 kDa RNA
Buffer: phosphate buffered saline, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Sep 22
Alu RNA pseudoknot alterations influence SRP9/SRP14 association. RNA (2025)
Gussakovsky D, Brown MJF, Pereira HS, Meier M, Padilla-Meier GP, Black NA, Booy EP, Stetefeld J, Patel TR, McKenna SA
RgGuinier 4.0 nm
Dmax 14.3 nm
VolumePorod 57 nm3