Browse by MODEL: Ab initio only

SASDJW8 – Monomeric human ganglioside-induced differentiation-associated protein 1, construct GDAP1∆303-358, mutant Y29E/C88A

Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆303-358, mutant Y29E/C88A experimental SAS data
GASBOR model
Sample: Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆303-358, mutant Y29E/C88A monomer, 35 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 300 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2020 Jun 28
Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations Frontiers in Molecular Biosciences 7 (2021)
Nguyen G, Sutinen A, Raasakka A, Muruganandam G, Loris R, Kursula P
RgGuinier 2.5 nm
Dmax 8.7 nm
VolumePorod 59 nm3

SASDJX8 – Dimeric human ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358

Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358 experimental SAS data
GASBOR model
Sample: Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358 dimer, 74 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 300 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2019 Jul 11
Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations Frontiers in Molecular Biosciences 7 (2021)
Nguyen G, Sutinen A, Raasakka A, Muruganandam G, Loris R, Kursula P
RgGuinier 3.5 nm
Dmax 10.8 nm
VolumePorod 130 nm3

SASDJY8 – Dimeric human ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358 with hexadecanedioic acid

Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358 experimental SAS data
GASBOR model
Sample: Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358 dimer, 74 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 300 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2019 Jul 11
Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations Frontiers in Molecular Biosciences 7 (2021)
Nguyen G, Sutinen A, Raasakka A, Muruganandam G, Loris R, Kursula P
RgGuinier 3.1 nm
Dmax 9.6 nm
VolumePorod 121 nm3

SASDJZ8 – Monomeric human ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358

Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358 experimental SAS data
GASBOR model
Sample: Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358 monomer, 37 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 300 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2019 Jul 11
Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations Frontiers in Molecular Biosciences 7 (2021)
Nguyen G, Sutinen A, Raasakka A, Muruganandam G, Loris R, Kursula P
RgGuinier 2.7 nm
Dmax 9.0 nm
VolumePorod 69 nm3

SASDJ29 – Monomeric human ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358 with hexadecanedioic acid

Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358 experimental SAS data
GASBOR model
Sample: Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358 monomer, 37 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 300 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2019 Jul 11
Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations Frontiers in Molecular Biosciences 7 (2021)
Nguyen G, Sutinen A, Raasakka A, Muruganandam G, Loris R, Kursula P
RgGuinier 2.5 nm
Dmax 8.6 nm
VolumePorod 65 nm3

SASDJK8 – N-terminal Angiopoietin-like protein 3 Hexamer

Angiopoietin-like protein 3 (N-terminal) experimental SAS data
DAMMIN model
Sample: Angiopoietin-like protein 3 (N-terminal) hexamer, 161 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl pH 7.5, 400 mM NaCl, 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Mar 12
Comparison of angiopoietin-like protein 3 and 4 reveals structural and mechanistic similarities. J Biol Chem :100312 (2021)
Gunn KH, Gutgsell AR, Xu Y, Johnson CV, Liu J, Neher SB
RgGuinier 5.6 nm
Dmax 34.0 nm
VolumePorod 380 nm3

SASDJL8 – N-terminal Angiopoietin-like protein 3 Trimer

Angiopoietin-related protein 3 experimental SAS data
DAMMIN model
Sample: Angiopoietin-related protein 3 trimer, 81 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl pH 7.5, 400 mM NaCl, 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Mar 12
Comparison of angiopoietin-like protein 3 and 4 reveals structural and mechanistic similarities. J Biol Chem :100312 (2021)
Gunn KH, Gutgsell AR, Xu Y, Johnson CV, Liu J, Neher SB
RgGuinier 4.6 nm
Dmax 21.5 nm
VolumePorod 71 nm3

SASDJM8 – N-terminal Angiopoietin-like protein 4 Trimer

Angiopoietin-related protein 4 experimental SAS data
DAMMIN model
Sample: Angiopoietin-related protein 4 trimer, 46 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl pH 7.4, 300 mM NaCl, 100 mM betaine, 500 mM arginine, pH: 7.4
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2017 Nov 8
Comparison of angiopoietin-like protein 3 and 4 reveals structural and mechanistic similarities. J Biol Chem :100312 (2021)
Gunn KH, Gutgsell AR, Xu Y, Johnson CV, Liu J, Neher SB
RgGuinier 4.7 nm
Dmax 16.0 nm
VolumePorod 69 nm3

SASDKF3 – Human telomere monomer G4 hybrid-2 form (2JSL)

Human telomere G-quadruplex hybrid-2 form experimental SAS data
DAMMIN model
Sample: Human telomere G-quadruplex hybrid-2 form monomer, 8 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Aug 14
The solution structures of higher-order human telomere G-quadruplex multimers. Nucleic Acids Res (2021)
Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO
RgGuinier 1.2 nm
Dmax 3.8 nm
VolumePorod 9 nm3

SASDKG3 – Human wild-type telomere 48-mer d(TTAGGG)8

Human Telomere Repeat (TTAGGG)8 experimental SAS data
DAMMIN model
Sample: Human Telomere Repeat (TTAGGG)8 monomer, 15 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Aug 14
The solution structures of higher-order human telomere G-quadruplex multimers. Nucleic Acids Res (2021)
Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO
RgGuinier 1.9 nm
Dmax 6.4 nm
VolumePorod 16 nm3