Browse by MODEL: Ab initio only

SASDVW2 – Fas-activated serine/threonine kinase/phosphoprotein FASTK (169-549)

Fas-activated serine/threonine kinase (amino acids 169-549) experimental SAS data
Sample: Fas-activated serine/threonine kinase (amino acids 169-549) monomer, 43 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl, 5% (v/v) Glycerol, 200 mM Ammonium Sulphate, 50 mM NaCl, 0.5 mM TCEP, 10 mM Glutamic acid, 10 mM Arginine;, pH: 8.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2020 Jan 31
Human FASTK protein
Daria Dawidziak
RgGuinier 2.8 nm
Dmax 12.0 nm
VolumePorod 67 nm3

SASDUA2 – The Z-DNA binding domains Zαβ of Z-DNA binding protein 1 (monomer)

Z-DNA-binding protein 1 experimental SAS data
DAMMIF model
Sample: Z-DNA-binding protein 1 monomer, 18 kDa Homo sapiens protein
Buffer: 20 mM Tris, 100 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction. Cell Death Dis 15(7):487 (2024)
Xie F, Wu D, Huang J, Liu X, Shen Y, Huang J, Su Z, Li J
RgGuinier 2.1 nm
Dmax 9.0 nm
VolumePorod 19 nm3

SASDUB2 – The Z-DNA binding domains Zαβ of Z-DNA binding protein 1 (dimer)

Z-DNA-binding protein 1 experimental SAS data
DAMMIF model
Sample: Z-DNA-binding protein 1 dimer, 37 kDa Homo sapiens protein
Buffer: 20 mM Tris, 100 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction. Cell Death Dis 15(7):487 (2024)
Xie F, Wu D, Huang J, Liu X, Shen Y, Huang J, Su Z, Li J
RgGuinier 3.1 nm
Dmax 13.0 nm
VolumePorod 48 nm3

SASDSP7 – 5’-terminal stem-loop 1 RNA element of SARS-CoV-2 (5_SL1)

5_SL1 experimental SAS data
DAMMIN model
Sample: 5_SL1 monomer, 9 kDa Severe acute respiratory … RNA
Buffer: 50 mM BisTris, 25 mM NaCl, pH: 6.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Dec 1
The 5'-terminal stem-loop RNA element of SARS-CoV-2 features highly dynamic structural elements that are sensitive to differences in cellular pH. Nucleic Acids Res (2024)
Toews S, Wacker A, Faison EM, Duchardt-Ferner E, Richter C, Mathieu D, Bottaro S, Zhang Q, Schwalbe H
RgGuinier 1.7 nm
Dmax 5.5 nm
VolumePorod 16 nm3

SASDPP7 – Amyloid Beta 1-42 (cluster 1, Set 2, final state)

Amyloid-beta precursor protein experimental SAS data
DAMMIN model
Sample: Amyloid-beta precursor protein, 5 kDa Homo sapiens protein
Buffer: 1 mM Hepes, 0.12 % NH4OH, pH: 10.7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Apr 11
Time-resolved small-angle X-ray scattering study of polymorphic nature of Aß42 oligomerisation
Tia Cheremnykh
RgGuinier 5.8 nm
Dmax 42.0 nm

SASDPQ7 – Amyloid Beta 1-42 (cluster 1, Set 3, final state)

Amyloid-beta precursor protein experimental SAS data
DAMMIN model
Sample: Amyloid-beta precursor protein, 5 kDa Homo sapiens protein
Buffer: 1 mM Hepes, 0.12 % NH4OH, pH: 10.7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Dec 13
Time-resolved small-angle X-ray scattering study of polymorphic nature of Aß42 oligomerisation
Tia Cheremnykh
RgGuinier 6.9 nm
Dmax 60.0 nm

SASDPR7 – Amyloid Beta 1-42 (cluster 2, Set 4, initial state)

Amyloid-beta precursor protein experimental SAS data
DAMMIN model
Sample: Amyloid-beta precursor protein, 5 kDa Homo sapiens protein
Buffer: 1 mM Hepes, 0.1 % NH4OH (pH∼10.7), pH: 10.7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Oct 31
Time-resolved small-angle X-ray scattering study of polymorphic nature of Aß42 oligomerisation
Tia Cheremnykh
RgGuinier 2.5 nm
Dmax 6.5 nm

SASDPS7 – Amyloid Beta 1-42 (cluster 2, Set 4, final state)

Amyloid-beta precursor protein experimental SAS data
DAMMIN model
Sample: Amyloid-beta precursor protein, 5 kDa Homo sapiens protein
Buffer: 1 mM Hepes, 0.1 % NH4OH (pH∼10.7), pH: 10.7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Nov 1
Time-resolved small-angle X-ray scattering study of polymorphic nature of Aß42 oligomerisation
Tia Cheremnykh
RgGuinier 3.7 nm
Dmax 9.1 nm

SASDPT7 – Amyloid Beta 1-42 (cluster 2, Set 5, final state)

Amyloid-beta precursor protein experimental SAS data
DAMMIN model
Sample: Amyloid-beta precursor protein, 5 kDa Homo sapiens protein
Buffer: 1 mM Hepes, 0.1 % NH4OH (pH∼10.7), pH: 10.7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Nov 1
Time-resolved small-angle X-ray scattering study of polymorphic nature of Aß42 oligomerisation
Tia Cheremnykh
RgGuinier 3.7 nm
Dmax 11.0 nm

SASDPU7 – Amyloid Beta 1-42 (cluster 1, Set 1, initial state)

Amyloid-beta precursor protein experimental SAS data
DAMMIN model
Sample: Amyloid-beta precursor protein, 5 kDa Homo sapiens protein
Buffer: 1 mM Hepes, 0.12 % NH4OH, pH: 10.7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Nov 2
Time-resolved small-angle X-ray scattering study of polymorphic nature of Aß42 oligomerisation
Tia Cheremnykh
RgGuinier 3.5 nm
Dmax 15.0 nm