Browse by MACROMOLECULE type: nucleic acid

SASDPK2 – Spiegelmer NOX-A12, 3.5 mg/ml

Spiegelmer NOX-A12 experimental SAS data
MC-FOLD | MC-SYM model
Sample: Spiegelmer NOX-A12 monomer, 15 kDa synthetic construct RNA
Buffer: 20 mM HEPES, pH: 7.5
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2009 Feb 20
Spiegelmers® NOX-E36 and NOX-A12
Al Kikhney, Bara Schmidt
RgGuinier 2.0 nm
Dmax 7.6 nm
VolumePorod 18 nm3

SASDNK7 – Guanine-rich DNA derived from the promoter region of c-MYC gene (MYC22-G14T/G23T) with KCl

MYC22-G14T/G23T experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: MYC22-G14T/G23T monomer, 7 kDa Homo sapiens DNA
Buffer: 50 mM Tris, 30 mM KCl, pH: 8
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2022 Feb 27
Small-angle X-ray scattering data of a guanine-rich DNA derived from the promoter region of c-MYC gene in solution Data in Brief :108285 (2022)
Miyauchi K, Imamura H, Yamaoki Y, Kato M
RgGuinier 1.3 nm
Dmax 5.3 nm
VolumePorod 9 nm3

SASDNL7 – Guanine-rich DNA derived from the promoter region of c-MYC gene (MYC22-G14T/G23T) with 18-crown-6

MYC22-G14T/G23T experimental SAS data
MYC22-G14T/G23T Kratky plot
Sample: MYC22-G14T/G23T monomer, 7 kDa Homo sapiens DNA
Buffer: 50 mM Tris, 100 mM 18-crown-6, pH: 8
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2022 Feb 27
Small-angle X-ray scattering data of a guanine-rich DNA derived from the promoter region of c-MYC gene in solution Data in Brief :108285 (2022)
Miyauchi K, Imamura H, Yamaoki Y, Kato M
RgGuinier 1.6 nm
Dmax 6.0 nm
VolumePorod 10 nm3

SASDN36 – Ox40 RNA (untranslated region, UTR) full-length

Ox40 3'UTR full-length experimental SAS data
Ox40 3'UTR full-length Kratky plot
Sample: Ox40 3'UTR full-length monomer, 50 kDa Mus musculus RNA
Buffer: 50 mM KCl, 25 mM sodium phosphate, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Jun 1
NMR-derived secondary structure of the full-length Ox40 mRNA 3'UTR and its multivalent binding to the immunoregulatory RBP Roquin. Nucleic Acids Res (2022)
Tants JN, Becker LM, McNicoll F, Müller-McNicoll M, Schlundt A
RgGuinier 3.7 nm
Dmax 12.0 nm
VolumePorod 115 nm3

SASDN46 – Ox40 RNA (untranslated region, UTR) alternative decay element (ADE)

Ox40 3 UTR ADE experimental SAS data
Ox40 3 UTR ADE Kratky plot
Sample: Ox40 3 UTR ADE monomer, 16 kDa Mus musculus RNA
Buffer: 50 mM KCl, 25 mM sodium phosphate, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Jun 1
NMR-derived secondary structure of the full-length Ox40 mRNA 3'UTR and its multivalent binding to the immunoregulatory RBP Roquin. Nucleic Acids Res (2022)
Tants JN, Becker LM, McNicoll F, Müller-McNicoll M, Schlundt A
RgGuinier 2.1 nm
Dmax 7.2 nm
VolumePorod 21 nm3

SASDN56 – Ox40 RNA (untranslated region, UTR) constitutive decay element (CDE)

Ox40 3 UTR CDE experimental SAS data
Ox40 3 UTR CDE Kratky plot
Sample: Ox40 3 UTR CDE monomer, 9 kDa Mus musculus RNA
Buffer: 50 mM KCl, 25 mM sodium phosphate, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Jun 1
NMR-derived secondary structure of the full-length Ox40 mRNA 3'UTR and its multivalent binding to the immunoregulatory RBP Roquin. Nucleic Acids Res (2022)
Tants JN, Becker LM, McNicoll F, Müller-McNicoll M, Schlundt A
RgGuinier 2.0 nm
Dmax 9.5 nm
VolumePorod 16 nm3

SASDN66 – Ox40 RNA (untranslated region, UTR) alternative and constitutive decay element (ADE-CDE)

Ox40 3 UTR ADE-CDE experimental SAS data
Ox40 3 UTR ADE-CDE Kratky plot
Sample: Ox40 3 UTR ADE-CDE monomer, 24 kDa Mus musculus RNA
Buffer: 50 mM KCl, 25 mM sodium phosphate, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Jun 1
NMR-derived secondary structure of the full-length Ox40 mRNA 3'UTR and its multivalent binding to the immunoregulatory RBP Roquin. Nucleic Acids Res (2022)
Tants JN, Becker LM, McNicoll F, Müller-McNicoll M, Schlundt A
RgGuinier 2.6 nm
Dmax 10.0 nm
VolumePorod 26 nm3

SASDN76 – Ox40 RNA (untranslated region, UTR) Bulge

Ox40 3 UTR Bulge experimental SAS data
Ox40 3 UTR Bulge Kratky plot
Sample: Ox40 3 UTR Bulge monomer, 11 kDa Mus musculus RNA
Buffer: 50 mM KCl, 25 mM sodium phosphate, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Jun 1
NMR-derived secondary structure of the full-length Ox40 mRNA 3'UTR and its multivalent binding to the immunoregulatory RBP Roquin. Nucleic Acids Res (2022)
Tants JN, Becker LM, McNicoll F, Müller-McNicoll M, Schlundt A
RgGuinier 1.8 nm
Dmax 6.5 nm
VolumePorod 17 nm3

SASDN86 – Ox40 RNA (untranslated region, UTR) Bulge with alternative decay element (Bulge-ADE)

Ox40 3 UTR Bulge-ADE experimental SAS data
Ox40 3 UTR Bulge-ADE Kratky plot
Sample: Ox40 3 UTR Bulge-ADE monomer, 27 kDa Mus musculus RNA
Buffer: 50 mM KCl, 25 mM sodium phosphate, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Jun 1
NMR-derived secondary structure of the full-length Ox40 mRNA 3'UTR and its multivalent binding to the immunoregulatory RBP Roquin. Nucleic Acids Res (2022)
Tants JN, Becker LM, McNicoll F, Müller-McNicoll M, Schlundt A
RgGuinier 3.3 nm
Dmax 12.5 nm
VolumePorod 37 nm3

SASDN96 – Ox40 RNA (untranslated region, UTR) Bulge with alternative and constitutive decay elements (Bulge-ADE-CDE)

Ox40 3 UTR Bulge-ADE-CDE experimental SAS data
Ox40 3 UTR Bulge-ADE-CDE Kratky plot
Sample: Ox40 3 UTR Bulge-ADE-CDE monomer, 35 kDa Mus musculus RNA
Buffer: 50 mM KCl, 25 mM sodium phosphate, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Jun 1
NMR-derived secondary structure of the full-length Ox40 mRNA 3'UTR and its multivalent binding to the immunoregulatory RBP Roquin. Nucleic Acids Res (2022)
Tants JN, Becker LM, McNicoll F, Müller-McNicoll M, Schlundt A
RgGuinier 3.4 nm
Dmax 11.0 nm
VolumePorod 46 nm3