Browse by ORGANISM: other species

SASDRM9 – Polyethylenimine-compacted single self-amplifying RNA for prophylactic and therapeutic application, specifically for vaccination

self-amplifying RNAlinear polyethylenimine experimental SAS data
DAMMIF model
Sample: Self-amplifying RNA monomer, 3030 kDa RNA
Linear polyethylenimine monomer, 25 kDa none (polymer)
Buffer: MBG buffer: 5% w/v D-Glucose, 10mM MES (2-(N-morpholino)ethanesulfonic acid) in double distillated sterile/RNAse free water, pH: 6.1
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Nov 10
Compact polyethylenimine-complexed mRNA vaccines Nature Nanotechnology (2025)
Moreno Herrero J, Stahl T, Erbar S, Maxeiner K, Schlegel A, Bacic T, Schumacher J, Cavalcanti L, Schroer M, Svergun D, Sahin U, Haas H
RgGuinier 12.0 nm
Dmax 40.0 nm
VolumePorod 9100 nm3

SASDXD5 – S.aureus PstA in a ligand-free state (cyclic-di-AMP receptor)

Cyclic-di-AMP receptor experimental SAS data
Cyclic-di-AMP receptor Kratky plot
Sample: Cyclic-di-AMP receptor trimer, 42 kDa Staphylococcus aureus protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Dec 11
Activation of a Secondary-Messenger Receptor via Allosteric Modulation of a Dynamic Conformational Ensemble. Angew Chem Int Ed Engl :e202509394 (2025)
Söldner B, Singh H, Akoury E, Witte G, Linser R
RgGuinier 2.7 nm
Dmax 11.0 nm
VolumePorod 91 nm3

SASDXE5 – S.aureus PstA with c-di-AMP (cyclic-di-AMP receptor)

Cyclic-di-AMP receptor experimental SAS data
Cyclic-di-AMP receptor Kratky plot
Sample: Cyclic-di-AMP receptor trimer, 42 kDa Staphylococcus aureus protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Dec 11
Activation of a Secondary-Messenger Receptor via Allosteric Modulation of a Dynamic Conformational Ensemble. Angew Chem Int Ed Engl :e202509394 (2025)
Söldner B, Singh H, Akoury E, Witte G, Linser R
RgGuinier 2.6 nm
Dmax 11.0 nm
VolumePorod 86 nm3

SASDW23 – SEC-SAXS of Trypanosoma cruzi Prolyl Oligopepetidase (TcPOP)

Prolyl endopeptidase experimental SAS data
ALPHAFOLD model
Sample: Prolyl endopeptidase monomer, 78 kDa Trypanosoma cruzi protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Apr 24
Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP. Nat Commun 16(1):7164 (2025)
Batra S, Olmo F, Ragan TJ, Kaplan M, Calvaresi V, Frank AM, Lancey C, Assadipapari M, Ying C, Struwe WB, Hesketh EL, Kelly JM, Barfod L, Campeotto I
RgGuinier 3.0 nm
Dmax 0.0 nm
VolumePorod 142 nm3

SASDW33 – STATIC-SAXS of Trypanosoma cruzi Prolyl Oligopepetidase (TcPOP)

Prolyl endopeptidase experimental SAS data
Prolyl endopeptidase Kratky plot
Sample: Prolyl endopeptidase monomer, 78 kDa Trypanosoma cruzi protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Apr 24
Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP. Nat Commun 16(1):7164 (2025)
Batra S, Olmo F, Ragan TJ, Kaplan M, Calvaresi V, Frank AM, Lancey C, Assadipapari M, Ying C, Struwe WB, Hesketh EL, Kelly JM, Barfod L, Campeotto I
RgGuinier 3.8 nm
Dmax 0.0 nm
VolumePorod 170 nm3

SASDX67 – Non Structural Protein 15 in complex with RNA 9mer

Non structural Protein 15 experimental SAS data
Non structural Protein 15 Kratky plot
Sample: Non structural Protein 15 monomer, 251 kDa Severe acute respiratory … protein
Buffer: 20mM HEPES, 150mM Nacl, pH: 7.5
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2024 Jun 14
Non Structural Protein 15 in Complex with RNA 9mer Oligo of SARS CoV 2
Hira Singh Gariya
RgGuinier 4.7 nm
Dmax 13.8 nm
VolumePorod 356 nm3

SASDSR7 – Gramicidin Synthetase 1 (GrsA) W239S mutant in the apo form without any substrates

Gramicidin S synthase 1 (W239S) experimental SAS data
BILBOMD model
Sample: Gramicidin S synthase 1 (W239S) monomer, 127 kDa Aneurinibacillus migulanus protein
Buffer: 20 mM Tris pH 7.5, 100 mM NaCl, 10 mM MgCl2, 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Mar 14
Resting state of GrsA is a combination of two constitutively inactive isoforms that manifest long-range allosteric effects in presence of aminoacid and ATP
Raktim Roy
RgGuinier 4.1 nm
Dmax 15.0 nm
VolumePorod 187 nm3

SASDSS7 – Gramicidin Synthetase 1 (GrsA) W239S mutant in the apo form in the presence of 4 molar excess of L-Tyrosine

Gramicidin S synthase 1 (W239S) experimental SAS data
Sample: Gramicidin S synthase 1 (W239S) monomer, 126 kDa Brevibacillus brevis protein
Buffer: 20 mM Tris pH 7.5, 100 mM NaCl, 10 mM MgCl2, 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Mar 14
Resting state of GrsA is a combination of two constitutively inactive isoforms that manifest long-range allosteric effects in presence of aminoacid and ATP
Raktim Roy
RgGuinier 4.3 nm
Dmax 15.4 nm
VolumePorod 186 nm3

SASDST7 – Gramicidin Synthetase 1 (GrsA) W239S mutant in the apo form in the presence of 4 molar excess of L-Tyrosine and ATP analog (AMPPCP)

Gramicidin S synthase 1 (W239S) experimental SAS data
Sample: Gramicidin S synthase 1 (W239S) monomer, 126 kDa Brevibacillus brevis protein
Buffer: 20 mM Tris pH 7.5, 100 mM NaCl, 10 mM MgCl2, 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Mar 14
Resting state of GrsA is a combination of two constitutively inactive isoforms that manifest long-range allosteric effects in presence of aminoacid and ATP
Raktim Roy
RgGuinier 4.2 nm
Dmax 16.0 nm
VolumePorod 186 nm3

SASDSU7 – Gramicidin Synthetase 1 (GrsA) W239S mutant in the holo form in the presence of 4 molar excess of L-Tyrosine

Gramicidin S synthase 1 (W239S) experimental SAS data
Sample: Gramicidin S synthase 1 (W239S) monomer, 126 kDa Brevibacillus brevis protein
Buffer: 20 mM Tris pH 7.5, 100 mM NaCl, 10 mM MgCl2, 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Mar 14
Resting state of GrsA is a combination of two constitutively inactive isoforms that manifest long-range allosteric effects in presence of aminoacid and ATP
Raktim Roy
RgGuinier 4.1 nm
Dmax 17.5 nm
VolumePorod 181 nm3