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19 hits found for Plasminogen

SASDF82 – ...plasminogen activator surface receptor, uPAR H47C-N259C, complex with urokinase-type plasminogen activator (Amino Terminal Fragment, ATF).

Urokinase plasminogen activator surface receptorUrokinase-type plasminogen activator (Amino Terminal Fragment) experimental SAS data
DAMMIN model
Sample: ...plasminogen activator surface receptor monomer, 37 kDa Homo sapiens protein
...plasminogen activator (Amino Terminal Fragment) monomer, 16 kDa Homo sapiens protein
Buffer: 20 mM PBS, 5 %(v/v) glycerol, 50 mM NaSO4,, pH: 7.4
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2011 Jun 18
Did evolution create a flexible ligand-binding cavity in the urokinase receptor through deletion of a plesiotypic disulfide bond? J Biol Chem (2019)
Leth JM, Mertens HDT, Leth-Espensen KZ, Jørgensen TJD, Ploug M
RgGuinier 2.6 nm
Dmax 8.2 nm
VolumePorod 102 nm3

SASDF92 – ...plasminogen activator surface receptor, uPAR, T51C-V70C

Urokinase plasminogen activator surface receptor experimental SAS data
DAMMIN model
Sample: ...plasminogen activator surface receptor monomer, 37 kDa Homo sapiens protein
Buffer: 20 mM PBS, 5 %(v/v) glycerol, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Dec 1
Did evolution create a flexible ligand-binding cavity in the urokinase receptor through deletion of a plesiotypic disulfide bond? J Biol Chem (2019)
Leth JM, Mertens HDT, Leth-Espensen KZ, Jørgensen TJD, Ploug M
RgGuinier 2.5 nm
Dmax 8.9 nm
VolumePorod 55 nm3

SASDFA2 – ...plasminogen activator surface receptor, uPAR T51C-V70C, complex with urokinase-type plasminogen activator (Amino Terminal Fragment, ATF).

Urokinase plasminogen activator surface receptorUrokinase-type plasminogen activator (Amino Terminal Fragment) experimental SAS data
DAMMIN model
Sample: ...plasminogen activator surface receptor monomer, 37 kDa Homo sapiens protein
...plasminogen activator (Amino Terminal Fragment) monomer, 16 kDa Homo sapiens protein
Buffer: 20 mM PBS, 5 %(v/v) glycerol, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Dec 1
Did evolution create a flexible ligand-binding cavity in the urokinase receptor through deletion of a plesiotypic disulfide bond? J Biol Chem (2019)
Leth JM, Mertens HDT, Leth-Espensen KZ, Jørgensen TJD, Ploug M
RgGuinier 2.6 nm
Dmax 8.5 nm
VolumePorod 77 nm3

SASDFB2 – ...plasminogen activator surface receptor, uPAR, K50C-V70C

Urokinase plasminogen activator surface receptor experimental SAS data
DAMMIN model
Sample: ...plasminogen activator surface receptor monomer, 37 kDa Homo sapiens protein
Buffer: 20 mM PBS, 5 %(v/v) glycerol, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 5
Did evolution create a flexible ligand-binding cavity in the urokinase receptor through deletion of a plesiotypic disulfide bond? J Biol Chem (2019)
Leth JM, Mertens HDT, Leth-Espensen KZ, Jørgensen TJD, Ploug M
RgGuinier 2.5 nm
Dmax 9.3 nm
VolumePorod 66 nm3

SASDFC2 – ...plasminogen activator surface receptor, uPAR K50C-V70C, complex with urokinase-type plasminogen activator (Amino Terminal Fragment, ATF).

Urokinase plasminogen activator surface receptorUrokinase-type plasminogen activator (Amino Terminal Fragment) experimental SAS data
DAMMIN model
Sample: ...plasminogen activator surface receptor monomer, 37 kDa Homo sapiens protein
...plasminogen activator (Amino Terminal Fragment) monomer, 16 kDa Homo sapiens protein
Buffer: 20 mM PBS, 5 %(v/v) glycerol, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 5
Did evolution create a flexible ligand-binding cavity in the urokinase receptor through deletion of a plesiotypic disulfide bond? J Biol Chem (2019)
Leth JM, Mertens HDT, Leth-Espensen KZ, Jørgensen TJD, Ploug M
RgGuinier 2.6 nm
Dmax 9.0 nm
VolumePorod 66 nm3

SASDZU3 – Plasminogen Athens

Plasminogen experimental SAS data
Plasminogen Kratky plot
Sample: Plasminogen monomer, 88 kDa Homo sapiens protein
Buffer: 10mM Na2HPO4, 1.8 mM KH2PO4, 2.7 mM KCl, 137 mM NaCl, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2025 Mar 14
...plasminogen across multiple resolution scales. Int J Biol Macromol :154885 (2026)
Kasiarova L, Verma N, Pinkas M, Henek T, Klumpler T, Chovancikova M, Reutova H, Kasparek P, Hlozankova M, Damborsky J, Novacek J, Hernychova L, Marek M
RgGuinier 5.4 nm
Dmax 16.8 nm
VolumePorod 119 nm3

SASDZV3 – Plasminogen Sigma

Plasminogen experimental SAS data
Plasminogen Kratky plot
Sample: Plasminogen monomer, 88 kDa Homo sapiens protein
Buffer: 10mM Na2HPO4, 1.8 mM KH2PO4, 2.7 mM KCl, 137 mM NaCl, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2025 Jan 14
...plasminogen across multiple resolution scales. Int J Biol Macromol :154885 (2026)
Kasiarova L, Verma N, Pinkas M, Henek T, Klumpler T, Chovancikova M, Reutova H, Kasparek P, Hlozankova M, Damborsky J, Novacek J, Hernychova L, Marek M
RgGuinier 3.4 nm
Dmax 10.2 nm
VolumePorod 132 nm3

SASDZW3 – Plasminogen Innovative Research

Plasminogen experimental SAS data
Plasminogen Kratky plot
Sample: Plasminogen monomer, 88 kDa Homo sapiens protein
Buffer: 10mM Na2HPO4, 1.8 mM KH2PO4, 2.7 mM KCl, 137 mM NaCl, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2026 Jan 22
...plasminogen across multiple resolution scales. Int J Biol Macromol :154885 (2026)
Kasiarova L, Verma N, Pinkas M, Henek T, Klumpler T, Chovancikova M, Reutova H, Kasparek P, Hlozankova M, Damborsky J, Novacek J, Hernychova L, Marek M
RgGuinier 5.7 nm
Dmax 19.3 nm
VolumePorod 276 nm3

SASDZX3 – Plasminogen Ivg

Plasminogen experimental SAS data
Plasminogen Kratky plot
Sample: Plasminogen monomer, 88 kDa Homo sapiens protein
Buffer: 10mM Na2HPO4, 1.8 mM KH2PO4, 2.7 mM KCl, 137 mM NaCl, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2026 Jan 22
...plasminogen across multiple resolution scales. Int J Biol Macromol :154885 (2026)
Kasiarova L, Verma N, Pinkas M, Henek T, Klumpler T, Chovancikova M, Reutova H, Kasparek P, Hlozankova M, Damborsky J, Novacek J, Hernychova L, Marek M
RgGuinier 3.6 nm
Dmax 10.5 nm
VolumePorod 142 nm3

SASDZY3 – Plasminogen Roche

Plasminogen experimental SAS data
Plasminogen Kratky plot
Sample: Plasminogen monomer, 88 kDa Homo sapiens protein
Buffer: 10mM Na2HPO4, 1.8 mM KH2PO4, 2.7 mM KCl, 137 mM NaCl, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2026 Jan 21
...plasminogen across multiple resolution scales. Int J Biol Macromol :154885 (2026)
Kasiarova L, Verma N, Pinkas M, Henek T, Klumpler T, Chovancikova M, Reutova H, Kasparek P, Hlozankova M, Damborsky J, Novacek J, Hernychova L, Marek M
RgGuinier 3.0 nm
Dmax 9.3 nm
VolumePorod 102 nm3

SASDZZ3 – Plasmin

Plasminogen experimental SAS data
Plasminogen Kratky plot
Sample: Plasminogen monomer, 88 kDa Homo sapiens protein
Buffer: 10mM Na2HPO4, 1.8 mM KH2PO4, 2.7 mM KCl, 137 mM NaCl, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2026 Jan 22
...plasminogen across multiple resolution scales. Int J Biol Macromol :154885 (2026)
Kasiarova L, Verma N, Pinkas M, Henek T, Klumpler T, Chovancikova M, Reutova H, Kasparek P, Hlozankova M, Damborsky J, Novacek J, Hernychova L, Marek M
RgGuinier 6.4 nm
Dmax 22.5 nm
VolumePorod 365 nm3

SASDZ24 – Plasminogen R561A point mutant

Plasminogen R561A - pointmutant experimental SAS data
Plasminogen R561A - pointmutant Kratky plot
Sample: Plasminogen R561A - pointmutant monomer, 88 kDa Homo sapiens, production … protein
Buffer: 10mM Na2HPO4, 1.8 mM KH2PO4, 2.7 mM KCl, 137 mM NaCl, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2026 Jan 13
...plasminogen across multiple resolution scales. Int J Biol Macromol :154885 (2026)
Kasiarova L, Verma N, Pinkas M, Henek T, Klumpler T, Chovancikova M, Reutova H, Kasparek P, Hlozankova M, Damborsky J, Novacek J, Hernychova L, Marek M
RgGuinier 3.7 nm
Dmax 12.4 nm
VolumePorod 162 nm3

SASDZ34 – Plasminogen (CAT) S741A point mutant

Plasminogen S741A - point mutant experimental SAS data
Plasminogen S741A - point mutant Kratky plot
Sample: Plasminogen S741A - point mutant monomer, 88 kDa Homo sapiens, production … protein
Buffer: 10mM Na2HPO4, 1.8 mM KH2PO4, 2.7 mM KCl, 137 mM NaCl, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2026 Jan 13
...plasminogen across multiple resolution scales. Int J Biol Macromol :154885 (2026)
Kasiarova L, Verma N, Pinkas M, Henek T, Klumpler T, Chovancikova M, Reutova H, Kasparek P, Hlozankova M, Damborsky J, Novacek J, Hernychova L, Marek M
RgGuinier 4.2 nm
Dmax 13.0 nm
VolumePorod 201 nm3

SASDAT4 – uPAR wild-type

Urokinase plasminogen activator surface receptor experimental SAS data
DAMMIF model
Sample: ...plasminogen activator surface receptor monomer, 37 kDa Homo sapiens protein
Buffer: 25 mM Sodium Phosphate 5 % Glycerol 50 mM NaSO4, pH: 7.2
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2010 Jun 10
...plasminogen activator receptor (uPAR). J Biol Chem 287(41):34304-15 (2012)
Mertens HD, Kjaergaard M, Mysling S, Gårdsvoll H, Jørgensen TJ, Svergun DI, Ploug M
RgGuinier 2.8 nm
Dmax 9.7 nm
VolumePorod 69 nm3

SASDAU4 – uPAR H47C/N259C

Urokinase plasminogen activator surface receptor experimental SAS data
DAMMIF model
Sample: ...plasminogen activator surface receptor monomer, 37 kDa Homo sapiens protein
Buffer: 25 mM Sodium Phosphate 5 % Glycerol 50 mM NaSO4, pH: 7.2
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2010 Jun 10
...plasminogen activator receptor (uPAR). J Biol Chem 287(41):34304-15 (2012)
Mertens HD, Kjaergaard M, Mysling S, Gårdsvoll H, Jørgensen TJ, Svergun DI, Ploug M
RgGuinier 2.2 nm
Dmax 7.0 nm
VolumePorod 57 nm3

SASDAV4 – uPAR wild-type AE105 complex

Urokinase plasminogen activator surface receptorsynthetic peptide AE105 experimental SAS data
Urokinase plasminogen activator surface receptor synthetic peptide AE105 Kratky plot
Sample: ...plasminogen activator surface receptor monomer, 37 kDa Homo sapiens protein
synthetic peptide AE105 monomer, 1 kDa protein
Buffer: 25 mM Sodium Phosphate 5 % Glycerol 50 mM NaSO4, pH: 7.2
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2010 Jun 10
...plasminogen activator receptor (uPAR). J Biol Chem 287(41):34304-15 (2012)
Mertens HD, Kjaergaard M, Mysling S, Gårdsvoll H, Jørgensen TJ, Svergun DI, Ploug M
RgGuinier 2.5 nm
Dmax 8.5 nm
VolumePorod 61 nm3

SASDAW4 – uPAR wild-type AE234 complex

Urokinase plasminogen activator surface receptorsynthetic peptide AE234 experimental SAS data
Urokinase plasminogen activator surface receptor synthetic peptide AE234 Kratky plot
Sample: ...plasminogen activator surface receptor monomer, 37 kDa Homo sapiens protein
synthetic peptide AE234 monomer, 1 kDa protein
Buffer: 25 mM Sodium Phosphate 5 % Glycerol 50 mM NaSO4, pH: 7.2
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2010 Jun 10
...plasminogen activator receptor (uPAR). J Biol Chem 287(41):34304-15 (2012)
Mertens HD, Kjaergaard M, Mysling S, Gårdsvoll H, Jørgensen TJ, Svergun DI, Ploug M
RgGuinier 2.4 nm
Dmax 8.3 nm
VolumePorod 57 nm3

SASDAX4 – uPAR wild-type ATF complex

Urokinase plasminogen activator surface receptorUrokinase-type plasminogen activator experimental SAS data
Urokinase plasminogen activator surface receptor Urokinase-type plasminogen activator Kratky plot
Sample: ...plasminogen activator surface receptor monomer, 37 kDa Homo sapiens protein
...plasminogen activator monomer, 49 kDa Homo sapiens protein
Buffer: 25 mM Sodium Phosphate 5 % Glycerol 50 mM NaSO4, pH: 7.2
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2010 Jun 10
...plasminogen activator receptor (uPAR). J Biol Chem 287(41):34304-15 (2012)
Mertens HD, Kjaergaard M, Mysling S, Gårdsvoll H, Jørgensen TJ, Svergun DI, Ploug M
RgGuinier 2.8 nm
Dmax 9.4 nm
VolumePorod 102 nm3

SASDJW5 – Plasminogen activator inhibitor-1 (PAI-1) W175F bound to nanobody Nb93

Plasminogen activator inhibitor 1VHH-s-a93 (Ig module Nb93) experimental SAS data
OTHER model
Sample: Plasminogen activator inhibitor 1 monomer, 43 kDa Homo sapiens protein
VHH-s-a93 (Ig module Nb93) monomer, 13 kDa Vicugna pacos protein
Buffer: 30 mM BIS-TRIS pH 5.5, 300 mM sodium chloride, 5% v/v glycerol, pH: 5.5
Experiment: SAXS data collected at SWING, SOLEIL on 2019 Dec 5
Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity International Journal of Molecular Sciences 21(16):5859 (2020)
Sillen M, Weeks S, Strelkov S, Declerck P
RgGuinier 2.9 nm
Dmax 9.7 nm
VolumePorod 80 nm3