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28 hits found for human telomeric g-quadruplex

SASDY63 – human telomeric g-quadruplex (Tel50)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 2.1 nm

SASDY73 – human telomeric g-quadruplex (Tel26)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex monomer, 8 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 1.3 nm

SASDY83 – human telomeric g-quadruplex Tel50+BRACO-19 (1:2)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
RgGuinier 2.0 nm

SASDY93 – human telomeric g-quadruplex Tel50+BRACO-19 (1:3)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
RgGuinier 2.0 nm

SASDYA3 – human telomeric g-quadruplex Tel50+BRACO-19 (1:4)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 2.0 nm

SASDYB3 – human telomeric g-quadruplex Tel50+PhenDC3 (1:2)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 2.0 nm

SASDYC3 – human telomeric g-quadruplex Tel50+PhenDC3 (1:3)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 2.0 nm

SASDYD3 – human telomeric g-quadruplex Tel50+PhenDC3 (1:4)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 2.0 nm

SASDYE3 – human telomeric G-quadruplex Tel50+RHPS4 (1:2)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 2.0 nm

SASDKF3 – Human telomere monomer G4 hybrid-2 form (2JSL)

Human telomere G-quadruplex hybrid-2 form experimental SAS data
DAMMIN model
Sample: Human telomere G-quadruplex hybrid-2 form monomer, 8 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Aug 14
...human telomere G-quadruplex multimers. Nucleic Acids Res (2021)
Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO
RgGuinier 1.2 nm
Dmax 3.8 nm
VolumePorod 9 nm3

SASDYF3 – human telomeric g-quadruplex Tel50+RHPS4(1:3)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 2.0 nm

SASDKG3 – Human wild-type telomere 48-mer d(TTAGGG)8

Human Telomere Repeat (TTAGGG)8 experimental SAS data
DAMMIN model
Sample: Human Telomere Repeat (TTAGGG)8 monomer, 15 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Aug 14
...human telomere G-quadruplex multimers. Nucleic Acids Res (2021)
Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO
RgGuinier 1.9 nm
Dmax 6.4 nm
VolumePorod 16 nm3

SASDYG3 – human telomeric g-quadruplex Tel50+RHPS4(1:4)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 2.0 nm

SASDKH3 – Human wild-type telomere 72mer d(TTAGGG)12

Human Telomere Repeat (TTAGGG)12 experimental SAS data
DAMMIF model
Sample: Human Telomere Repeat (TTAGGG)12 monomer, 23 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Aug 14
...human telomere G-quadruplex multimers. Nucleic Acids Res (2021)
Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO
RgGuinier 2.5 nm
Dmax 8.7 nm
VolumePorod 26 nm3

SASDYH3 – human telomeric g-quadruplex Tel50+SYUIQ-5 (1:2)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 2.0 nm

SASDKJ3 – Human telomere DNA d(TTAGGG)96

Human Telomere 96mer experimental SAS data
DAMMIF model
Sample: Human Telomere 96mer monomer, 31 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Feb 19
...human telomere G-quadruplex multimers. Nucleic Acids Res (2021)
Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO
RgGuinier 3.2 nm
Dmax 10.9 nm
VolumePorod 38 nm3

SASDYJ3 – human telomeric g-quadruplex Tel50+SYUIQ-5 (1:3)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 1.9 nm

SASDYK3 – human telomeric g-quadruplex Tel50+SYUIQ-5 (1:4)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 1.9 nm

SASDYL3 – human telomeric g-quadruplex Tel26+BRACO-19 (1:1)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex monomer, 8 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 1.3 nm

SASDYM3 – human telomeric g-quadruplex Tel26+BRACO-19 (1:2)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex monomer, 8 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 1.3 nm

SASDYN3 – human telomeric g-quadruplex Tel26+PhenDC3 (1:1)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex monomer, 8 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 1.3 nm

SASDYP3 – human telomeric g-quadruplex Tel26+RHPS4 (1:1)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex monomer, 8 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 1.3 nm

SASDYQ3 – human telomeric g-quadruplex Tel26+PhenDC3 (1:2)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex monomer, 8 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 1.3 nm

SASDYR3 – human telomeric g-quadruplex Tel26+RHPS4 (1:2)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex monomer, 8 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 1.3 nm

SASDYS3 – human telomeric g-quadruplex Tel26+SYUIQ-5 (1:1)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex monomer, 8 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 1.3 nm

SASDYT3 – human telomeric g-quadruplex Tel26+SYUIQ-5 (1:2)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex monomer, 8 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2024 Jul 12
Tel50 + ligands
valeria libera
RgGuinier 1.3 nm

SASDZF4 – human telomeric g-quadruplex Tel50+BRACO-19 (1:2)

human telomeric g-quadruplexhuman telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex , 16 kDa DNA
human telomeric g-quadruplex monomer, 8 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2026 Mar 30
Tel50 + ligands (BR19)
valeria libera
RgGuinier 2.0 nm

SASDZG4 – human telomeric g-quadruplex Tel50+BRACO-19 (1:3)

human telomeric g-quadruplex experimental SAS data
human telomeric g-quadruplex Kratky plot
Sample: human telomeric g-quadruplex monomer, 8 kDa DNA
Buffer: 5 mM KH2PO4/K2HPO4, pH: 7
Experiment: SAXS data collected at BM29, ESRF on 2026 Mar 30
Tel50 + ligands (BR19)
valeria libera
RgGuinier 2.0 nm