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9 hits found for Monsen

SASDKF3 – Human telomere monomer G4 hybrid-2 form (2JSL)

Human telomere G-quadruplex hybrid-2 form experimental SAS data
DAMMIN model
Sample: Human telomere G-quadruplex hybrid-2 form monomer, 8 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Aug 14
The solution structures of higher-order human telomere G-quadruplex multimers. Nucleic Acids Res (2021)
Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO
RgGuinier 1.2 nm
Dmax 3.8 nm
VolumePorod 9 nm3

SASDKG3 – Human wild-type telomere 48-mer d(TTAGGG)8

Human Telomere Repeat (TTAGGG)8 experimental SAS data
DAMMIN model
Sample: Human Telomere Repeat (TTAGGG)8 monomer, 15 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Aug 14
The solution structures of higher-order human telomere G-quadruplex multimers. Nucleic Acids Res (2021)
Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO
RgGuinier 1.9 nm
Dmax 6.4 nm
VolumePorod 16 nm3

SASDKH3 – Human wild-type telomere 72mer d(TTAGGG)12

Human Telomere Repeat (TTAGGG)12 experimental SAS data
DAMMIF model
Sample: Human Telomere Repeat (TTAGGG)12 monomer, 23 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Aug 14
The solution structures of higher-order human telomere G-quadruplex multimers. Nucleic Acids Res (2021)
Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO
RgGuinier 2.5 nm
Dmax 8.7 nm
VolumePorod 26 nm3

SASDKJ3 – Human telomere DNA d(TTAGGG)96

Human Telomere 96mer experimental SAS data
DAMMIF model
Sample: Human Telomere 96mer monomer, 31 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Feb 19
The solution structures of higher-order human telomere G-quadruplex multimers. Nucleic Acids Res (2021)
Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO
RgGuinier 3.2 nm
Dmax 10.9 nm
VolumePorod 38 nm3

SASDHM3 – Human Telomerase Reverse Transcriptase Core Promoter G-rich Region (hTERT_WT) DNA

Human Telomerase Reverse Transcriptase Core Promoter G-rich Region experimental SAS data
DAMMIF model
Sample: Human Telomerase Reverse Transcriptase Core Promoter G-rich Region monomer, 22 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Oct 5
The hTERT core promoter forms three parallel G-quadruplexes. Nucleic Acids Res (2020)
Monsen RC, DeLeeuw L, Dean WL, Gray RD, Sabo TM, Chakravarthy S, Chaires JB, Trent JO
RgGuinier 2.2 nm
Dmax 8.1 nm
VolumePorod 28 nm3

SASDHN3 – Antiparallel Hairpin (AH) DNA

Antiparallel Hairpin experimental SAS data
DAMMIF model
Sample: Antiparallel Hairpin monomer, 21 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Nov 3
The hTERT core promoter forms three parallel G-quadruplexes. Nucleic Acids Res (2020)
Monsen RC, DeLeeuw L, Dean WL, Gray RD, Sabo TM, Chakravarthy S, Chaires JB, Trent JO
RgGuinier 2.5 nm
Dmax 8.1 nm
VolumePorod 28 nm3

SASDHP3 – Optimized Parallel DNA

Optimized Parallel experimental SAS data
DAMFILT model
Sample: Optimized Parallel monomer, 18 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Nov 3
The hTERT core promoter forms three parallel G-quadruplexes. Nucleic Acids Res (2020)
Monsen RC, DeLeeuw L, Dean WL, Gray RD, Sabo TM, Chakravarthy S, Chaires JB, Trent JO
RgGuinier 1.7 nm
Dmax 5.0 nm
VolumePorod 17 nm3

SASDHQ3 – Human Telomerase Reverse Transcriptase Core Promoter (hTERT) PQS2-PQS3 region, WT_PQS23

hTERT core promoter PQS2-PQS3 region experimental SAS data
DAMFILT model
Sample: hTERT core promoter PQS2-PQS3 region monomer, 14 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Nov 3
The hTERT core promoter forms three parallel G-quadruplexes. Nucleic Acids Res (2020)
Monsen RC, DeLeeuw L, Dean WL, Gray RD, Sabo TM, Chakravarthy S, Chaires JB, Trent JO
RgGuinier 1.7 nm
Dmax 5.4 nm
VolumePorod 18 nm3

SASDHR3 – Antiparallel Hairpin PQS2-PQS3 segment DNA, AH_PQS23

Antiparallel Hairpin PQS2-PQS3 segment experimental SAS data
DAMFILT model
Sample: Antiparallel Hairpin PQS2-PQS3 segment monomer, 14 kDa synthetic construct DNA
Buffer: 6 mM Na2HPO4, 2 mM NaH2PO4, 1 mM Na2EDTA, 185 mM KCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Nov 3
The hTERT core promoter forms three parallel G-quadruplexes. Nucleic Acids Res (2020)
Monsen RC, DeLeeuw L, Dean WL, Gray RD, Sabo TM, Chakravarthy S, Chaires JB, Trent JO
RgGuinier 2.0 nm
Dmax 6.4 nm
VolumePorod 18 nm3