SASBDB entries for UniProt ID:

SASDNR6 – Retinoblastoma protein/Early E1A protein (RB-E1A) complex at 0.7 mg/ml

UniProt ID: None (None-None) Retinoblastoma-associated protein

UniProt ID: None (None-None) Early E1A protein
Retinoblastoma-associated proteinEarly E1A protein experimental SAS data
Retinoblastoma-associated protein Early E1A protein Kratky plot
Sample: Retinoblastoma-associated protein monomer, 41 kDa Homo sapiens protein
Early E1A protein monomer, 13 kDa Human adenovirus C … protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Jul 14
Conformational buffering underlies functional selection in intrinsically disordered protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bernadó P, Pappu RV, Holehouse AS, Daughdrill GW, Chemes LB
RgGuinier 2.9 nm
Dmax 10.0 nm
VolumePorod 80 nm3

SASDNS6 – Retinoblastoma protein/Early E1A protein (RB-E1A) complex at 1.4 mg/ml

UniProt ID: None (None-None) Retinoblastoma-associated protein

UniProt ID: None (None-None) Early E1A protein
Retinoblastoma-associated proteinEarly E1A protein experimental SAS data
Retinoblastoma-associated protein Early E1A protein Kratky plot
Sample: Retinoblastoma-associated protein monomer, 41 kDa Homo sapiens protein
Early E1A protein monomer, 13 kDa Human adenovirus C … protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Jul 14
Conformational buffering underlies functional selection in intrinsically disordered protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bernadó P, Pappu RV, Holehouse AS, Daughdrill GW, Chemes LB
RgGuinier 3.0 nm
Dmax 12.0 nm
VolumePorod 84 nm3

SASDNT6 – Retinoblastoma protein/Early E1A protein (RB-E1A) complex at 2.7 mg/ml

UniProt ID: None (None-None) Retinoblastoma-associated protein

UniProt ID: None (None-None) Early E1A protein
Retinoblastoma-associated proteinEarly E1A protein experimental SAS data
Retinoblastoma-associated protein Early E1A protein Kratky plot
Sample: Retinoblastoma-associated protein monomer, 41 kDa Homo sapiens protein
Early E1A protein monomer, 13 kDa Human adenovirus C … protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Jul 14
Conformational buffering underlies functional selection in intrinsically disordered protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bernadó P, Pappu RV, Holehouse AS, Daughdrill GW, Chemes LB
RgGuinier 3.3 nm
Dmax 17.0 nm
VolumePorod 93 nm3

SASDNU6 – Retinoblastoma protein/Early E1A protein (RB-E1A) complex - merged data from concentration series measurements

UniProt ID: None (None-None) Retinoblastoma-associated protein

UniProt ID: None (None-None) Early E1A protein
Retinoblastoma-associated proteinEarly E1A protein experimental SAS data
Retinoblastoma-associated protein Early E1A protein Kratky plot
Sample: Retinoblastoma-associated protein monomer, 41 kDa Homo sapiens protein
Early E1A protein monomer, 13 kDa Human adenovirus C … protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Jul 14
Conformational buffering underlies functional selection in intrinsically disordered protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bernadó P, Pappu RV, Holehouse AS, Daughdrill GW, Chemes LB
RgGuinier 3.0 nm
Dmax 12.0 nm
VolumePorod 84 nm3

SASDNV6 – Early E1A protein, SEC-SAXS data

UniProt ID: None (None-None) Early E1A protein
Early E1A protein experimental SAS data
Early E1A protein Kratky plot
Sample: Early E1A protein monomer, 13 kDa Human adenovirus C … protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at SWING, SOLEIL on 2019 Mar 24
Conformational buffering underlies functional selection in intrinsically disordered protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bernadó P, Pappu RV, Holehouse AS, Daughdrill GW, Chemes LB
RgGuinier 3.6 nm
Dmax 17.5 nm
VolumePorod 45 nm3

SASDNW6 – AIP56, an AB-toxin from Photobacterium damselae subsp. piscicida

UniProt ID: A9ZTI0 (17-512) Apoptosis inducing protein
Apoptosis inducing protein experimental SAS data
OTHER model
Sample: Apoptosis inducing protein monomer, 57 kDa Photobacterium damselae subsp. … protein
Buffer: 50 mM Hepes, 500 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2019 Apr 13
Unconventional structure and mechanisms for membrane interaction and translocation of the NF-κB-targeting toxin AIP56. Nat Commun 14(1):7431 (2023)
Lisboa J, Pereira C, Pinto RD, Rodrigues IS, Pereira LMG, Pinheiro B, Oliveira P, Pereira PJB, Azevedo JE, Durand D, Benz R, do Vale A, Dos Santos NMS
RgGuinier 2.8 nm
Dmax 9.5 nm
VolumePorod 76 nm3

SASDN57 – beta-hexosyl transferase (23-594), 1 mg/mL

UniProt ID: Q564N5 (23-594) Beta-galactosidase-like enzyme
Beta-galactosidase-like enzyme experimental SAS data
Beta-galactosidase-like enzyme Kratky plot
Sample: Beta-galactosidase-like enzyme dimer, 129 kDa Hamamotoa singularis protein
Buffer: 5 mM sodium phosphate, pH: 5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, Oak Ridge National Laboratory on 2018 Jun 25
Structural analysis and functional evaluation of the disordered ß–hexosyltransferase region from Hamamotoa (Sporobolomyces) singularis Frontiers in Bioengineering and Biotechnology 11 (2023)
Dagher S, Vaishnav A, Stanley C, Meilleur F, Edwards B, Bruno-Bárcena J
RgGuinier 3.9 nm
Dmax 12.4 nm
VolumePorod 238 nm3

SASDN67 – beta-hexosyl transferase (23-594), 4 mg/mL

UniProt ID: Q564N5 (23-594) Beta-galactosidase-like enzyme
Beta-galactosidase-like enzyme experimental SAS data
Beta-galactosidase-like enzyme Kratky plot
Sample: Beta-galactosidase-like enzyme dimer, 129 kDa Hamamotoa singularis protein
Buffer: 5 mM sodium phosphate, pH: 5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, Oak Ridge National Laboratory on 2018 Jun 25
Structural analysis and functional evaluation of the disordered ß–hexosyltransferase region from Hamamotoa (Sporobolomyces) singularis Frontiers in Bioengineering and Biotechnology 11 (2023)
Dagher S, Vaishnav A, Stanley C, Meilleur F, Edwards B, Bruno-Bárcena J
RgGuinier 3.7 nm
Dmax 12.5 nm
VolumePorod 236 nm3

SASDN77 – Truncated histone shaperone protein SET/TAF-Ib DC

UniProt ID: Q01105 (1-225) SET nuclear proto-oncogene
SET nuclear proto-oncogene experimental SAS data
AMBER model
Sample: SET nuclear proto-oncogene dimer, 53 kDa Homo sapiens protein
Buffer: Sodium phosphate buffer, pH: 6.3
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Nov 11
PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ Computational and Structural Biotechnology Journal (2022)
Casado-Combreras M, Rivero-Rodríguez F, Elena-Real C, Molodenskiy D, Díaz-Quintana A, Martinho M, Gerbaud G, González-Arzola K, Velázquez-Campoy A, Svergun D, Belle V, De la Rosa M, Díaz-Moreno I
RgGuinier 3.1 nm
Dmax 9.7 nm
VolumePorod 87 nm3

SASDN87 – Mixture 1:2 of truncated histone shaperone protein SET/TAF-Ib DC with cytochrome c

UniProt ID: P99999 (None-None) Cytochrome c

UniProt ID: Q01105 (1-225) SET nuclear proto-oncogene
Cytochrome cSET nuclear proto-oncogene experimental SAS data
SASREF model
Sample: Cytochrome c dimer, 24 kDa Homo sapiens protein
SET nuclear proto-oncogene dimer, 53 kDa Homo sapiens protein
Buffer: Sodium phosphate buffer, pH: 6.3
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Nov 11
PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ Computational and Structural Biotechnology Journal (2022)
Casado-Combreras M, Rivero-Rodríguez F, Elena-Real C, Molodenskiy D, Díaz-Quintana A, Martinho M, Gerbaud G, González-Arzola K, Velázquez-Campoy A, Svergun D, Belle V, De la Rosa M, Díaz-Moreno I
RgGuinier 4.2 nm
Dmax 16.0 nm