SASBDB entries for UniProt ID:

SASDUB2 – The Z-DNA binding domains Zαβ of Z-DNA binding protein 1 (dimer)

UniProt ID: Q9H171 (1-165) Z-DNA-binding protein 1
Z-DNA-binding protein 1 experimental SAS data
DAMMIF model
Sample: Z-DNA-binding protein 1 dimer, 37 kDa Homo sapiens protein
Buffer: 20 mM Tris, 100 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Mar 23
ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction. Cell Death Dis 15(7):487 (2024)
Xie F, Wu D, Huang J, Liu X, Shen Y, Huang J, Su Z, Li J
RgGuinier 3.1 nm
Dmax 13.0 nm
VolumePorod 48 nm3

SASDUF2 – Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1-DH/PH-DEP1 (WT))

UniProt ID: Q8TCU6 (38-499) Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein experimental SAS data
EOM/RANCH model
Sample: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein monomer, 54 kDa Homo sapiens protein
Buffer: 20 mM HEPES pH 7, 300 mM NaCl, 2% glycerol, 2 mM DTT, pH: 7
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Oct 8
Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4 eLife 12 (2024)
Ravala S, Adame-Garcia S, Li S, Chen C, Cianfrocco M, Silvio Gutkind J, Cash J, Tesmer J
RgGuinier 3.0 nm
Dmax 9.7 nm
VolumePorod 79 nm3

SASDUG2 – Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein A170K mutant (P-Rex1-DH/PH-DEP1-A170K)

UniProt ID: Q8TCU6 (38-499) Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (A170K)
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (A170K) experimental SAS data
EOM/RANCH model
Sample: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (A170K) monomer, 54 kDa Homo sapiens protein
Buffer: 20 mM HEPES pH 7, 300 mM NaCl, 2% glycerol, 2 mM DTT, pH: 7
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Nov 24
Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4 eLife 12 (2024)
Ravala S, Adame-Garcia S, Li S, Chen C, Cianfrocco M, Silvio Gutkind J, Cash J, Tesmer J
RgGuinier 2.9 nm
Dmax 9.0 nm
VolumePorod 76 nm3

SASDUH2 – Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein L177E mutant (P-Rex1-DH/PH-DEP1-L177E)

UniProt ID: Q8TCU6 (38-499) Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (L177E)
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (L177E) experimental SAS data
EOM/RANCH model
Sample: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (L177E) monomer, 54 kDa Homo sapiens protein
Buffer: 20 mM HEPES pH 7, 300 mM NaCl, 2% glycerol, 2 mM DTT, pH: 7
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Oct 8
Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4 eLife 12 (2024)
Ravala S, Adame-Garcia S, Li S, Chen C, Cianfrocco M, Silvio Gutkind J, Cash J, Tesmer J
RgGuinier 3.1 nm
Dmax 11.0 nm
VolumePorod 88 nm3

SASDUJ2 – Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein I409A mutant (P-Rex1-DH/PH-DEP1-I409A)

UniProt ID: Q8TCU6 (38-499) Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (I409A)
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (I409A) experimental SAS data
EOM/RANCH model
Sample: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (I409A) monomer, 54 kDa Homo sapiens protein
Buffer: 20 mM HEPES pH 7, 300 mM NaCl, 2% glycerol, 2 mM DTT, pH: 7
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Oct 8
Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4 eLife 12 (2024)
Ravala S, Adame-Garcia S, Li S, Chen C, Cianfrocco M, Silvio Gutkind J, Cash J, Tesmer J
RgGuinier 3.0 nm
Dmax 10.4 nm
VolumePorod 79 nm3

SASDUK2 – Histone deacetylase 7

UniProt ID: Q9FH09 (5-383) Histone deacetylase 7
Histone deacetylase 7 experimental SAS data
COOT model
Sample: Histone deacetylase 7 monomer, 44 kDa Arabidopsis thaliana protein
Buffer: 20 mM Tris, 150 mM NaCl, 1 mM β-mercaptoethanol, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2023 Jan 24
Structure-function analyses reveal Arabidopsis thaliana HDA7 to be an inactive histone deacetylase Current Research in Structural Biology :100136 (2024)
Saharan K, Baral S, Shaikh N, Vasudevan D
RgGuinier 3.0 nm
Dmax 10.2 nm
VolumePorod 85 nm3

SASDUL2 – mRNA capping enzyme small subunit

UniProt ID: Q8V4X6 (1-287) Virus termination factor small subunit
Virus termination factor small subunit experimental SAS data
DAMFILT model
Sample: Virus termination factor small subunit monomer, 33 kDa Monkeypox virus (strain … protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2024 Jan 4
Structural basis of the monkeypox virus mRNA cap N7 methyltransferase complex. Emerg Microbes Infect 13(1):2369193 (2024)
Chen A, Fang N, Zhang Z, Wen Y, Shen Y, Zhang Y, Zhang L, Zhao G, Ding J, Li J
RgGuinier 2.4 nm
Dmax 6.8 nm
VolumePorod 51 nm3

SASDUM2 – mRNA capping enzyme MTase

UniProt ID: Q8V4X6 (1-287) Virus termination factor small subunit

UniProt ID: Q8V4Y7 (546-845) mRNA-capping enzyme catalytic subunit
Virus termination factor small subunitmRNA-capping enzyme catalytic subunit experimental SAS data
DAMFILT model
Sample: Virus termination factor small subunit monomer, 33 kDa Monkeypox virus (strain … protein
MRNA-capping enzyme catalytic subunit monomer, 35 kDa Monkeypox virus (strain … protein
Buffer: 20 mM Tris, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2024 Jan 4
Structural basis of the monkeypox virus mRNA cap N7 methyltransferase complex. Emerg Microbes Infect 13(1):2369193 (2024)
Chen A, Fang N, Zhang Z, Wen Y, Shen Y, Zhang Y, Zhang L, Zhao G, Ding J, Li J
RgGuinier 2.9 nm
Dmax 10.1 nm
VolumePorod 106 nm3

SASDUT2 – Recombinant short complement regulator SCR-17/18H (produced in Pichia pastoris with PNGase F treatment)

UniProt ID: P08603 (988-1107) Complement factor H
Complement factor H experimental SAS data
PYMOL model
Sample: Complement factor H monomer, 17 kDa Homo sapiens protein
Buffer: 10 mM HEPES, 137 mM NaCl, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2020 Jan 20
The SCR-17 and SCR-18 glycans in human complement Factor H enhance its regulatory function. J Biol Chem :107624 (2024)
Gao X, Iqbal H, Yu DQ, Gor J, Coker AR, Perkins SJ
RgGuinier 3.1 nm
Dmax 10.5 nm
VolumePorod 46 nm3

SASDUU2 – Recombinant short complement regulator SCR-17/18, without glycan (produced in Escherichia coli)

UniProt ID: P08603 (985-1108) Complement factor H
Complement factor H experimental SAS data
PYMOL model
Sample: Complement factor H monomer, 14 kDa Homo sapiens protein
Buffer: 10 mM HEPES, 137 mM NaCl, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2020 Jan 20
The SCR-17 and SCR-18 glycans in human complement Factor H enhance its regulatory function. J Biol Chem :107624 (2024)
Gao X, Iqbal H, Yu DQ, Gor J, Coker AR, Perkins SJ
RgGuinier 2.3 nm
Dmax 7.0 nm
VolumePorod 19 nm3