SASBDB entries for UniProt ID:

SASDVJ6 – apo Dipeptidyl peptidase 8 (DPP8 apo)

UniProt ID: Q6V1X1-1 (1-898) Isoform 1 of Dipeptidyl peptidase 8
Isoform 1 of Dipeptidyl peptidase 8 experimental SAS data
BILBOMD model
Sample: Isoform 1 of Dipeptidyl peptidase 8 dimer, 208 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM DTT, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2023 Oct 14
Computational study of DPP8 and DPP9: fundamental insights and inhibitor design University of Antwerp PhD thesis c:irua:209673 (2024)
Olivier Beyens, Yann Sterckx
RgGuinier 4.2 nm
Dmax 13.6 nm
VolumePorod 271 nm3

SASDVK6 – Dipeptidyl peptidase 8 (DPP8) with compound 42

UniProt ID: Q6V1X1-1 (None-None) Isoform 1 of Dipeptidyl peptidase 8
Isoform 1 of Dipeptidyl peptidase 8 experimental SAS data
BILBOMD model
Sample: Isoform 1 of Dipeptidyl peptidase 8 dimer, 208 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM DTT, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2023 Oct 14
Computational study of DPP8 and DPP9: fundamental insights and inhibitor design University of Antwerp PhD thesis c:irua:209673 (2024)
Olivier Beyens, Yann Sterckx
RgGuinier 4.2 nm
Dmax 13.7 nm
VolumePorod 277 nm3

SASDVL6 – apo Dipeptidyl peptidase 9 (DPP9 apo)

UniProt ID: Q86TI2-1 (1-863) Isoform 1 of Dipeptidyl peptidase 9
Isoform 1 of Dipeptidyl peptidase 9 experimental SAS data
BILBOMD model
Sample: Isoform 1 of Dipeptidyl peptidase 9 dimer, 198 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM DTT, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2023 Sep 23
Computational study of DPP8 and DPP9: fundamental insights and inhibitor design University of Antwerp PhD thesis c:irua:209673 (2024)
Olivier Beyens, Yann Sterckx
RgGuinier 4.2 nm
Dmax 13.3 nm
VolumePorod 290 nm3

SASDVM6 – Dipeptidyl peptidase 9 (DPP9) with compound 42

UniProt ID: Q86TI2-1 (1-863) Isoform 1 of Dipeptidyl peptidase 9
Isoform 1 of Dipeptidyl peptidase 9 experimental SAS data
BILBOMD model
Sample: Isoform 1 of Dipeptidyl peptidase 9 dimer, 198 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM DTT, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2023 Sep 23
Computational study of DPP8 and DPP9: fundamental insights and inhibitor design University of Antwerp PhD thesis c:irua:209673 (2024)
Olivier Beyens, Yann Sterckx
RgGuinier 4.1 nm
Dmax 12.5 nm
VolumePorod 274 nm3

SASDVQ6 – Retriever complex

UniProt ID: Q7Z3J2 (1-963) VPS35 endosomal protein-sorting factor-like

UniProt ID: Q9UBQ0 (1-182) Vacuolar protein sorting-associated protein 29

UniProt ID: O14972 (1-297) Vacuolar protein sorting-associated protein 26C
VPS35 endosomal protein-sorting factor-likeVacuolar protein sorting-associated protein 29Vacuolar protein sorting-associated protein 26C experimental SAS data
ALPHAFOLD model
Sample: VPS35 endosomal protein-sorting factor-like monomer, 110 kDa Homo sapiens protein
Vacuolar protein sorting-associated protein 29 monomer, 21 kDa Homo sapiens protein
Vacuolar protein sorting-associated protein 26C monomer, 33 kDa Homo sapiens protein
Buffer: 50 mM Tris, 200 mM NaCl, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Apr 28
Selective cargo and membrane recognition by SNX17 regulates its interaction with Retriever EMBO Reports (2024)
Martín-González A, Méndez-Guzmán I, Zabala-Zearreta M, Quintanilla A, García-López A, Martínez-Lombardía E, Albesa-Jové D, Acosta J, Lucas M
RgGuinier 5.2 nm
Dmax 21.5 nm
VolumePorod 256 nm3

SASDVR6 – Vacuolar protein sorting-associated protein 26C (VPS26C)

UniProt ID: O14972 (1-297) Vacuolar protein sorting-associated protein 26C
Vacuolar protein sorting-associated protein 26C experimental SAS data
ALPHAFOLD model
Sample: Vacuolar protein sorting-associated protein 26C monomer, 33 kDa Homo sapiens protein
Buffer: 50 mM Tris, 150 mM NaCl, 1 mM TCEP,, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2021 Apr 22
Selective cargo and membrane recognition by SNX17 regulates its interaction with Retriever EMBO Reports (2024)
Martín-González A, Méndez-Guzmán I, Zabala-Zearreta M, Quintanilla A, García-López A, Martínez-Lombardía E, Albesa-Jové D, Acosta J, Lucas M
RgGuinier 2.7 nm
Dmax 9.4 nm
VolumePorod 44 nm3

SASDVV6 – Extended single alpha-helix (SAH) region of Drebrin

UniProt ID: Q16643 (173-238) Drebrin
Drebrin experimental SAS data
OTHER [STATIC IMAGE] model
Sample: Drebrin monomer, 10 kDa Homo sapiens protein
Buffer: 17 mM NaH2PO4, 3 mM Na2HPO4, 50 mM NaCl, pH: 6
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Jul 7
Dynamic Interchange of Local Residue-Residue Interactions in the Largely Extended Single Alpha-Helix in Drebrin Biochemical Journal (2025)
Varga S, Péterfia B, Dudola D, Farkas V, Jeffries C, Permi P, Gáspári Z
RgGuinier 3.0 nm
Dmax 12.0 nm
VolumePorod 18 nm3

SASDVW6 – Monomeric Adhesion-associated domain in MUC4 and Other Proteins (AMOP-domain) of Isthmin-1

UniProt ID: B1AKI9 (263-464) Isthmin-1 AMOP-domain
Isthmin-1 AMOP-domain experimental SAS data
Isthmin-1 AMOP-domain Kratky plot
Sample: Isthmin-1 AMOP-domain monomer, 25 kDa Homo sapiens protein
Buffer: 20 mM HEPES 100 mM NaCl, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, Pennsylvania State University on 2023 Jun 21
Crystal structure of Isthmin-1 and reassessment of its functional role in pre-adipocyte signaling. Nat Commun 16(1):3580 (2025)
Li T, Stayrook SE, Li W, Wang Y, Li H, Zhang J, Liu Y, Klein DE
RgGuinier 2.3 nm
Dmax 9.7 nm
VolumePorod 45264 nm3

SASDVX6 – Monomeric Adhesion-associated domain in MUC4 and Other Proteins (AMOP-domain) of Isthmin-1, I455E, F458E douple mutant

UniProt ID: B1AKI9 (263-464) L-AMOP-IFEE
L-AMOP-IFEE experimental SAS data
L-AMOP-IFEE Kratky plot
Sample: L-AMOP-IFEE monomer, 25 kDa Homo sapiens protein
Buffer: 20 mM HEPES 100 mM NaCl, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, Pennsylvania State University on 2023 Jun 21
Crystal structure of Isthmin-1 and reassessment of its functional role in pre-adipocyte signaling. Nat Commun 16(1):3580 (2025)
Li T, Stayrook SE, Li W, Wang Y, Li H, Zhang J, Liu Y, Klein DE
RgGuinier 2.4 nm
Dmax 8.8 nm
VolumePorod 46874 nm3

SASDVC7 – Tetrameric L-threonine dehydratase biosynthetic IlvA (EcIlvA) from Eschericia coli

UniProt ID: P04968 (2-514) L-threonine dehydratase biosynthetic IlvA
L-threonine dehydratase biosynthetic IlvA experimental SAS data
CHIMERA model
Sample: L-threonine dehydratase biosynthetic IlvA tetramer, 233 kDa Escherichia coli (strain … protein
Buffer: 20 mM KPO4, 200 mM NaCl, 0.1 mM TCEP,, pH: 7.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Oct 14
Isoleucine Binding and Regulation of Escherichia coli and Staphylococcus aureus Threonine Dehydratase (IlvA). Biochemistry (2025)
Yun MK, Subramanian C, Miller K, Jackson P, Radka CD, Rock CO
RgGuinier 4.5 nm
Dmax 15.6 nm
VolumePorod 284 nm3