SASBDB entries for UniProt ID:

SASDSU2 – Mus musculus Iho1 coiled-coiled with N-terminal SUMO-tag

UniProt ID: Q6PDM4 (109-267) Interactor of HORMAD1 protein 1 (M198V, V230I)
Interactor of HORMAD1 protein 1 (M198V, V230I) experimental SAS data
Sample: Interactor of HORMAD1 protein 1 (M198V, V230I) tetramer, 127 kDa Mus musculus protein
Buffer: 25 mM HEPES-NaOH, 500 mM NaCl, 5 mM EDTA, 5% glycerol, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2023 Apr 14
Evolutionary conservation of the structure and function of meiotic Rec114-Mei4 and Mer2 complexes. Genes Dev 37(11-12):535-553 (2023)
Daccache D, De Jonge E, Liloku P, Mechleb K, Haddad M, Corthaut S, Sterckx YG, Volkov AN, Claeys Bouuaert C
RgGuinier 7.2 nm
Dmax 25.5 nm

SASDS26 – DNA binding domain of PALB2 (partner and localizer of BRCA2) in 160 mM NaCl

UniProt ID: Q86YC2 (1-200) Partner and localizer of BRCA2
Partner and localizer of BRCA2 experimental SAS data
DNA binding domain of PALB2 (partner and localizer of BRCA2) in 160 mM NaCl Rg histogram
Sample: Partner and localizer of BRCA2 dimer, 46 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 160 mM NaCl, 0.5 mM TCEP, pH: 7.4
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Nov 11
The strand exchange domain of tumor suppressor PALB2 is intrinsically disordered and promotes oligomerization-dependent DNA compaction. iScience 27(12):111259 (2024)
Kyriukha Y, Watkins MB, Redington JM, Chintalapati N, Ganti A, Dastvan R, Uversky VN, Hopkins JB, Pozzi N, Korolev S
RgGuinier 4.7 nm
Dmax 21.3 nm
VolumePorod 197 nm3

SASDSL7 – Tandem WW domains of Pre-mRNA-processing factor 40 homolog A (PRPF40A) in complex with Splicing factor 1 (SF1) C-terminal proline repeat

UniProt ID: O75400 (141-236) Pre-mRNA-processing factor 40 homolog A

UniProt ID: Q15637 (575-590) Splicing factor 1
Pre-mRNA-processing factor 40 homolog ASplicing factor 1 experimental SAS data
Pre-mRNA-processing factor 40 homolog A Splicing factor 1 Kratky plot
Sample: Pre-mRNA-processing factor 40 homolog A monomer, 11 kDa Homo sapiens protein
Splicing factor 1 monomer, 2 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 100 mM NaCl, 0.5 mM DTT, pH: 6.5
Experiment: SAXS data collected at BM29, ESRF on 2020 Sep 19
Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs. Nat Commun 15(1):3888 (2024)
Martínez-Lumbreras S, Träger LK, Mulorz MM, Payr M, Dikaya V, Hipp C, König J, Sattler M
RgGuinier 1.9 nm
Dmax 6.9 nm
VolumePorod 19 nm3

SASDSR8 – Calcium/calmodulin-dependent protein kinase kinase 1 (CaMKK1)

UniProt ID: Q8N5S9 (67-481) Calcium/calmodulin-dependent protein kinase kinase 1 (M474L)
Calcium/calmodulin-dependent protein kinase kinase 1 (M474L) experimental SAS data
Calcium/calmodulin-dependent protein kinase kinase 1 (M474L) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase kinase 1 (M474L) monomer, 46 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl, 150 mM NaCl, 1 mM TCEP, 3% (w/v) glycerol, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Aug 17
14-3-3 protein inhibits CaMKK1 by blocking the kinase active site with its last two C-terminal helices. Protein Sci :e4805 (2023)
Petrvalska O, Honzejkova K, Koupilova N, Herman P, Obsilova V, Obsil T
RgGuinier 3.2 nm
Dmax 10.7 nm
VolumePorod 114 nm3

SASDT43 – Teneurin-3 A1B1 isoform in 5 mM EDTA - 1.30 mg/mL

UniProt ID: Q9WTS6-1 (343-2715) Isoform A1B1 of Teneurin-3
Isoform A1B1 of Teneurin-3 experimental SAS data
Isoform A1B1 of Teneurin-3 Kratky plot
Sample: Isoform A1B1 of Teneurin-3 dimer, 545 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 5 mM EDTA, pH: 7.8
Experiment: SAXS data collected at BM29, ESRF on 2022 Sep 10
Alternative splicing controls teneurin-3 compact dimer formation for neuronal recognition Nature Communications 15(1) (2024)
Gogou C, Beugelink J, Frias C, Kresik L, Jaroszynska N, Drescher U, Janssen B, Hindges R, Meijer D
RgGuinier 8.8 nm
Dmax 35.0 nm
VolumePorod 1035 nm3

SASDTB5 – Trypanosoma brucei gambiense variant surface glycoprotein 3.1

UniProt ID: M4N7P1 (1-482) Variant surface glycoprotein 3.1
Variant surface glycoprotein 3.1 experimental SAS data
BILBOMD model
Sample: Variant surface glycoprotein 3.1 dimer, 103 kDa Trypanosoma brucei gambiense protein
Buffer: 20 mM HEPES, 150 mM NaCl, 3% glycerol, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2022 Sep 8
Beyond the VSG Layer: Exploring the Role of Intrinsic Disorder in the Invariant Surface Glycoproteins of African Trypanosomes. PLoS Pathog 20(4):e1012186 (2024)
Sülzen H, Volkov AN, Geens R, Zahedifard F, Stijlemans B, Zoltner M, Magez S, Sterckx YG, Zoll S
RgGuinier 4.7 nm
Dmax 17.0 nm
VolumePorod 149 nm3

SASDTF5 – SARS-CoV-2 N-protein (N1-365, amino acids 1-365): 49 µM

UniProt ID: P0DTC9 (1-365) Nucleoprotein
Nucleoprotein experimental SAS data
Nucleoprotein Kratky plot
Sample: Nucleoprotein tetramer, 163 kDa Severe acute respiratory … protein
Buffer: 100 mM Tris-HCl, 150 mM NaCl, 1 mM EDTA, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 May 13
Dynamic ensembles of SARS-CoV-2 N-protein reveal head-to-head coiled-coil-driven oligomerization and phase separation. Nucleic Acids Res 53(11) (2025)
Hernandez G, Martins ML, Fernandes NP, Veloso T, Lopes J, Gomes T, Cordeiro TN
RgGuinier 5.8 nm
Dmax 24.0 nm
VolumePorod 181 nm3

SASDUF9 – Mononuclear iron bound form of pigeon ISCA1 under 180 mT magnetic field for 60min

UniProt ID: P0DN75 (2-132) Pigeon iron-sulfur cluster assembly 1 homolog, mitochondrial
Pigeon iron-sulfur cluster assembly 1 homolog, mitochondrial experimental SAS data
Pigeon iron-sulfur cluster assembly 1 homolog, mitochondrial Kratky plot
Sample: Pigeon iron-sulfur cluster assembly 1 homolog, mitochondrial, 15 kDa Columba livia protein
Buffer: 20 mM Tris-HCl, 0.15 M NaCl, 10 mM 3-mercapto-1,2-propanediol, pH: 8
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2021 Jun 8
A hidden property of the iron-sulfur protein in the mononuclear iron-bound state: species-dependent structural ordering induced by magnetic fields. FEBS J (2025)
Arai S, Soga S, Hirai M, Kobayashi R, Masai H, Kimura K, Maeda K, Nagashima H
RgGuinier 2.8 nm
Dmax 10.5 nm
VolumePorod 85 nm3

SASDUM9 – Br-labelled Importin Beta Binding domain (IBB) from importin subunit alpha-1 in 0.5 M Urea

UniProt ID: J3QLL0 (2-73) importin-beta-binding domain of importin subunit alpha-1 labelled with unnatural amino acid diBrK
importin-beta-binding domain of importin subunit alpha-1 labelled with unnatural amino acid diBrK experimental SAS data
importin-beta-binding domain of importin subunit alpha-1 labelled with unnatural amino acid diBrK Kratky plot
Sample: Importin-beta-binding domain of importin subunit alpha-1 labelled with unnatural amino acid diBrK monomer, 8 kDa Homo sapiens protein
Buffer: phosphate buffered saline containing 0.5 M urea, 0.3 M KCl, 5 mM DTT, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2021 Dec 19
A genetically encoded anomalous SAXS ruler to probe the dimensions of intrinsically disordered proteins. Proc Natl Acad Sci U S A 121(50):e2415220121 (2024)
Yu M, Gruzinov AY, Ruan H, Scheidt T, Chowdhury A, Giofrè S, Mohammed ASA, Caria J, Sauter PF, Svergun DI, Lemke EA
RgGuinier 2.6 nm
Dmax 13.8 nm
VolumePorod 18 nm3

SASDVL2 – Ternary complex consisted of Human Chatepsin G, Neutrophil elastase and S.aureus MAP domain-containing protein

UniProt ID: P08311 (22-245) Cathepsin G

UniProt ID: A0A0H3JUK5 (32-146) MAP domain-containing protein

UniProt ID: P08246 (31-249) Neutrophil elastase
Cathepsin GMAP domain-containing proteinNeutrophil elastase experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Cathepsin G monomer, 25 kDa Homo sapiens protein
MAP domain-containing protein monomer, 13 kDa Staphylococcus aureus (strain … protein
Neutrophil elastase monomer, 23 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 140 mM NaCl, pH: 7.4
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Jun 3
S. aureus Eap is a polyvalent inhibitor of neutrophil serine proteases. J Biol Chem 300(9):107627 (2024)
Mishra N, Gido CD, Herdendorf TJ, Hammel M, Hura GL, Fu ZQ, Geisbrecht BV
RgGuinier 2.8 nm
Dmax 9.4 nm
VolumePorod 77 nm3