Small Angle Scattering Biological Data Bank SASBDB

SASBDB entries for UniProt ID:

SASDSX9 – SARS-CoV-2 N-protein (N1-245, residues 1-245) L223P, L227P and L230P triple mutant: 294 µM

UniProt ID: P0DTC9 (1-245) Nucleoprotein (L223P, L227P, L230P)

Nucleoprotein (L223P, L227P, L230P) experimental SAS data

Nucleoprotein (L223P, L227P, L230P) Kratky plot

Sample:	Nucleoprotein (L223P, L227P, L230P) monomer, 27 kDa Severe acute respiratory … protein
Buffer:	100 mM Tris-HCl, 150 mM NaCl, 1 mM EDTA, pH: 8
Experiment:	SAXS data collected at B21, Diamond Light Source on 2023 Jan 29

Dynamic ensembles of SARS-CoV-2 N-protein reveal head-to-head coiled-coil-driven oligomerization and phase separation. Nucleic Acids Res 53(11) (2025)
Hernandez G, Martins ML, Fernandes NP, Veloso T, Lopes J, Gomes T, Cordeiro TN

R_g^Guinier	4.4	nm
D_max	19.0	nm
Volume^Porod	68	nm³

SASDSY9 – SARS-CoV-2 N-protein (N1-245, residues 1-245) L223P, L227P and L230P triple mutant: 400 µM

UniProt ID: P0DTC9 (1-245) Nucleoprotein (L223P, L227P, L230P)

Sample:	Nucleoprotein (L223P, L227P, L230P) monomer, 27 kDa Severe acute respiratory … protein
Buffer:	100 mM Tris-HCl, 150 mM NaCl, 1 mM EDTA, pH: 8
Experiment:	SAXS data collected at B21, Diamond Light Source on 2023 Jan 29

R_g^Guinier	4.6	nm
D_max	19.0	nm
Volume^Porod	75	nm³

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