SASBDB entries for UniProt ID:

SASDRW9 – Regulator of telomere elongation helicase 1, HHD1-HHD2 fragment

UniProt ID: Q9NZ71-6 (889-1147) Regulator of telomere elongation helicase 1 (Isoform 6, 889-1147)
Regulator of telomere elongation helicase 1 (Isoform 6, 889-1147) experimental SAS data
Regulator of telomere elongation helicase 1, HHD1-HHD2 fragment Rg histogram
Sample: Regulator of telomere elongation helicase 1 (Isoform 6, 889-1147) monomer, 28 kDa Homo sapiens protein
Buffer: 50 mM Hepes, 150 mM NaCl,10 (v/v)% glycerol, 1 mM TCEP, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Mar 22
Structural and biochemical characterization of the C‐terminal region of the human RTEL 1 helicase Protein Science 33(9) (2024)
Cortone G, Graewert M, Kanade M, Longo A, Hegde R, González‐Magaña A, Chaves‐Arquero B, Blanco F, Napolitano L, Onesti S
RgGuinier 3.4 nm
Dmax 10.1 nm
VolumePorod 36 nm3

SASDST2 – Saccharomyces pombe Rec15 coiled-coiled with N-terminal SUMO-tag

UniProt ID: Q09094 (1-161) Meiotic recombination protein rec15
Meiotic recombination protein rec15 experimental SAS data
3D-DART model
Sample: Meiotic recombination protein rec15 tetramer, 128 kDa Schizosaccharomyces pombe (strain … protein
Buffer: 25 mM HEPES-NaOH, 500 mM NaCl, 5 mM EDTA, 5% glycerol, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2023 Apr 14
Evolutionary conservation of the structure and function of meiotic Rec114-Mei4 and Mer2 complexes. Genes Dev 37(11-12):535-553 (2023)
Daccache D, De Jonge E, Liloku P, Mechleb K, Haddad M, Corthaut S, Sterckx YG, Volkov AN, Claeys Bouuaert C
RgGuinier 6.9 nm
Dmax 26.5 nm

SASDSS8 – Phosphorylated Calcium/calmodulin-dependent protein kinase 1 (pCaMKK1)

UniProt ID: Q8N5S9 (67-481) Calcium/calmodulin-dependent protein kinase kinase 1 (M474L)
Calcium/calmodulin-dependent protein kinase kinase 1 (M474L) experimental SAS data
Calcium/calmodulin-dependent protein kinase kinase 1 (M474L) Kratky plot
Sample: Calcium/calmodulin-dependent protein kinase kinase 1 (M474L) monomer, 46 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl, 150 mM NaCl, 1 mM TCEP, 3% (w/v) glycerol, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Aug 17
14-3-3 protein inhibits CaMKK1 by blocking the kinase active site with its last two C-terminal helices. Protein Sci :e4805 (2023)
Petrvalska O, Honzejkova K, Koupilova N, Herman P, Obsilova V, Obsil T
RgGuinier 3.0 nm
Dmax 10.5 nm
VolumePorod 97 nm3

SASDTZ2 – Teneurin-3 A1B1 isoform in 2 mM calcium - 1.24 mg/mL

UniProt ID: Q9WTS6-1 (343-2715) Isoform A1B1 of Teneurin-3
Isoform A1B1 of Teneurin-3 experimental SAS data
Isoform A1B1 of Teneurin-3 Kratky plot
Sample: Isoform A1B1 of Teneurin-3 dimer, 545 kDa Mus musculus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 2 mM CaCl2, pH: 7.8
Experiment: SAXS data collected at BM29, ESRF on 2022 Sep 10
Alternative splicing controls teneurin-3 compact dimer formation for neuronal recognition Nature Communications 15(1) (2024)
Gogou C, Beugelink J, Frias C, Kresik L, Jaroszynska N, Drescher U, Janssen B, Hindges R, Meijer D
RgGuinier 7.9 nm
Dmax 33.0 nm
VolumePorod 1133 nm3

SASDT75 – Trypanosoma brucei gambiense invariant surface glycoprotein 43 (ISG43)

UniProt ID: C9ZNA4 (22-349) T. brucei spp.-specific protein
T. brucei spp.-specific protein experimental SAS data
BILBOMD model
Sample: T. brucei spp.-specific protein monomer, 38 kDa Trypanosoma brucei gambiense … protein
Buffer: 20 mM HEPES, 150 mM NaCl, 3% glycerol, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2022 Sep 8
Beyond the VSG Layer: Exploring the Role of Intrinsic Disorder in the Invariant Surface Glycoproteins of African Trypanosomes. PLoS Pathog 20(4):e1012186 (2024)
Sülzen H, Volkov AN, Geens R, Zahedifard F, Stijlemans B, Zoltner M, Magez S, Sterckx YG, Zoll S
RgGuinier 3.2 nm
Dmax 11.5 nm
VolumePorod 53 nm3

SASDTG5 – SARS-CoV-2 N-protein (N1-365, amino acids 1-365): 103 µM

UniProt ID: P0DTC9 (1-365) Nucleoprotein
Nucleoprotein experimental SAS data
Nucleoprotein Kratky plot
Sample: Nucleoprotein tetramer, 163 kDa Severe acute respiratory … protein
Buffer: 100 mM Tris-HCl, 150 mM NaCl, 1 mM EDTA, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 May 13
Dynamic ensembles of SARS-CoV-2 N-protein reveal head-to-head coiled-coil-driven oligomerization and phase separation. Nucleic Acids Res 53(11) (2025)
Hernandez G, Martins ML, Fernandes NP, Veloso T, Lopes J, Gomes T, Cordeiro TN
RgGuinier 6.2 nm
Dmax 25.0 nm
VolumePorod 215 nm3

SASDUH4 – Tandem of WW domains of Pre-mRNA-processing factor 40 homolog A (PRPF40A) in HEPES buffer

UniProt ID: O75400 (141-236) Pre-mRNA-processing factor 40 homolog A
Pre-mRNA-processing factor 40 homolog A experimental SAS data
Pre-mRNA-processing factor 40 homolog A Kratky plot
Sample: Pre-mRNA-processing factor 40 homolog A monomer, 11 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 100 mM NaCl, 1 mM DTT, pH: 6.6
Experiment: SAXS data collected at Rigaku BioSAXS-1000, Technische Universität München on 2024 Mar 8
Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs. Nat Commun 15(1):3888 (2024)
Martínez-Lumbreras S, Träger LK, Mulorz MM, Payr M, Dikaya V, Hipp C, König J, Sattler M
RgGuinier 2.0 nm
Dmax 6.3 nm
VolumePorod 18 nm3

SASDUG9 – Mononuclear iron bound form of human ISCA1 under geomagnetic field

UniProt ID: Q9BUE6 (2-129) Human Iron-sulfur cluster assembly 1 homolog, mitochondrial
Human Iron-sulfur cluster assembly 1 homolog, mitochondrial experimental SAS data
DAMMIN model
Sample: Human Iron-sulfur cluster assembly 1 homolog, mitochondrial, 14 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 0.15 M NaCl, 10 mM 3-mercapto-1,2-propanediol, pH: 8
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2024 Apr 29
A hidden property of the iron-sulfur protein in the mononuclear iron-bound state: species-dependent structural ordering induced by magnetic fields. FEBS J (2025)
Arai S, Soga S, Hirai M, Kobayashi R, Masai H, Kimura K, Maeda K, Nagashima H
RgGuinier 4.1 nm
Dmax 16.4 nm
VolumePorod 105 nm3

SASDUQ9 – Wild-type Importin Beta Binding domain (IBB) from importin subunit alpha-1 in 2 M Urea

UniProt ID: J3QLL0 (2-73) Importin subunit alpha-1
Importin subunit alpha-1 experimental SAS data
Importin subunit alpha-1 Kratky plot
Sample: Importin subunit alpha-1 monomer, 9 kDa Homo sapiens protein
Buffer: phosphate buffered saline containing 2 M urea, 0.3 M KCl, 5 mM DTT, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Jul 1
A genetically encoded anomalous SAXS ruler to probe the dimensions of intrinsically disordered proteins. Proc Natl Acad Sci U S A 121(50):e2415220121 (2024)
Yu M, Gruzinov AY, Ruan H, Scheidt T, Chowdhury A, Giofrè S, Mohammed ASA, Caria J, Sauter PF, Svergun DI, Lemke EA
RgGuinier 2.7 nm
Dmax 11.8 nm
VolumePorod 22 nm3

SASDVM2 – Ternary complex consisted of Human Neutrophil elastase tetramer and S.aureus Protein map Eap4-domain-4 (Δ347-476Δ) (Complex: NE/Eap4/NE)

UniProt ID: P08246 (31-249) Neutrophil elastase

UniProt ID: Q99QS1 (374-476) Protein map
Neutrophil elastaseProtein map experimental SAS data
PHENIX model
Sample: Neutrophil elastase tetramer, 93 kDa Homo sapiens protein
Protein map dimer, 24 kDa Staphylococcus aureus (strain … protein
Buffer: 20 mM HEPES, 140 mM NaCl, pH: 7.4
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Jun 26
S. aureus Eap is a polyvalent inhibitor of neutrophil serine proteases. J Biol Chem 300(9):107627 (2024)
Mishra N, Gido CD, Herdendorf TJ, Hammel M, Hura GL, Fu ZQ, Geisbrecht BV
RgGuinier 3.7 nm
Dmax 11.0 nm
VolumePorod 163 nm3