SASBDB entries for UniProt ID:

SASDDF8 – Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1463E

UniProt ID: P16144-2 (1436-1666) Integrin beta-4 (1436-1666) R1463E
Integrin beta-4 (1436-1666) R1463E experimental SAS data
Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1463E Rg histogram
Sample: Integrin beta-4 (1436-1666) R1463E monomer, 26 kDa Homo sapiens protein
Buffer: 20 mM Sodium Phosphate 150 mM NaCl 5% glycerol 3 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Nov 26
Integrin α6β4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. Structure 27(6):952-964.e6 (2019)
Manso JA, Gómez-Hernández M, Carabias A, Alonso-García N, García-Rubio I, Kreft M, Sonnenberg A, de Pereda JM
RgGuinier 2.3 nm
Dmax 9.5 nm
VolumePorod 35 nm3

SASDDG8 – Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1463A

UniProt ID: P16144-2 (1436-1666) Integrin beta-4 (1436-1666) R1463A
Integrin beta-4 (1436-1666) R1463A experimental SAS data
Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1463A Rg histogram
Sample: Integrin beta-4 (1436-1666) R1463A monomer, 26 kDa Homo sapiens protein
Buffer: 20 mM Sodium Phosphate 150 mM NaCl 5% glycerol 3 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Nov 26
Integrin α6β4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. Structure 27(6):952-964.e6 (2019)
Manso JA, Gómez-Hernández M, Carabias A, Alonso-García N, García-Rubio I, Kreft M, Sonnenberg A, de Pereda JM
RgGuinier 2.4 nm
Dmax 9.5 nm
VolumePorod 36 nm3

SASDDH8 – Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant A1468R

UniProt ID: P16144-2 (1436-1666) Integrin beta-4 (1436-1666) A1468R
Integrin beta-4 (1436-1666) A1468R experimental SAS data
Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant A1468R Rg histogram
Sample: Integrin beta-4 (1436-1666) A1468R monomer, 26 kDa Homo sapiens protein
Buffer: 20 mM Sodium Phosphate 150 mM NaCl 5% glycerol 3 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Nov 26
Integrin α6β4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. Structure 27(6):952-964.e6 (2019)
Manso JA, Gómez-Hernández M, Carabias A, Alonso-García N, García-Rubio I, Kreft M, Sonnenberg A, de Pereda JM
RgGuinier 2.8 nm
Dmax 10.9 nm
VolumePorod 35 nm3

SASDDJ8 – Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant A1468D

UniProt ID: P16144-2 (1436-1666) Integrin beta-4 (1436-1666) A1468D
Integrin beta-4 (1436-1666) A1468D experimental SAS data
Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant A1468D Rg histogram
Sample: Integrin beta-4 (1436-1666) A1468D monomer, 26 kDa Homo sapiens protein
Buffer: 20 mM Sodium Phosphate 150 mM NaCl 5% glycerol 3 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Nov 26
Integrin α6β4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. Structure 27(6):952-964.e6 (2019)
Manso JA, Gómez-Hernández M, Carabias A, Alonso-García N, García-Rubio I, Kreft M, Sonnenberg A, de Pereda JM
RgGuinier 2.7 nm
Dmax 11.0 nm
VolumePorod 34 nm3

SASDDK8 – Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1475E

UniProt ID: P16144-2 (1436-1666) Integrin beta-4 (1436-1666) R1475E
Integrin beta-4 (1436-1666) R1475E experimental SAS data
Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1475E Rg histogram
Sample: Integrin beta-4 (1436-1666) R1475E monomer, 26 kDa Homo sapiens protein
Buffer: 20 mM Sodium Phosphate 150 mM NaCl 5% glycerol 3 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Nov 26
Integrin α6β4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. Structure 27(6):952-964.e6 (2019)
Manso JA, Gómez-Hernández M, Carabias A, Alonso-García N, García-Rubio I, Kreft M, Sonnenberg A, de Pereda JM
RgGuinier 2.6 nm
Dmax 9.5 nm
VolumePorod 42 nm3

SASDDL8 – Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1475A

UniProt ID: P16144-2 (1436-1666) Integrin beta-4 (1436-1666) R1475A
Integrin beta-4 (1436-1666) R1475A experimental SAS data
Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1475A Rg histogram
Sample: Integrin beta-4 (1436-1666) R1475A monomer, 26 kDa Homo sapiens protein
Buffer: 20 mM Sodium Phosphate 150 mM NaCl 5% glycerol 3 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Nov 26
Integrin α6β4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. Structure 27(6):952-964.e6 (2019)
Manso JA, Gómez-Hernández M, Carabias A, Alonso-García N, García-Rubio I, Kreft M, Sonnenberg A, de Pereda JM
RgGuinier 2.4 nm
Dmax 9.5 nm
VolumePorod 35 nm3

SASDDM8 – Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1542E

UniProt ID: P16144-2 (1436-1666) Integrin beta-4 (1436-1666) R1542E
Integrin beta-4 (1436-1666) R1542E experimental SAS data
Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1542E Rg histogram
Sample: Integrin beta-4 (1436-1666) R1542E monomer, 26 kDa Homo sapiens protein
Buffer: 20 mM Sodium Phosphate 150 mM NaCl 5% glycerol 3 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Nov 26
Integrin α6β4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. Structure 27(6):952-964.e6 (2019)
Manso JA, Gómez-Hernández M, Carabias A, Alonso-García N, García-Rubio I, Kreft M, Sonnenberg A, de Pereda JM
RgGuinier 2.3 nm
Dmax 9.5 nm
VolumePorod 35 nm3

SASDDN8 – Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1542A

UniProt ID: P16144-2 (1436-1666) Integrin beta-4 (1436-1666) R1542A
Integrin beta-4 (1436-1666) R1542A experimental SAS data
Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant R1542A Rg histogram
Sample: Integrin beta-4 (1436-1666) R1542A monomer, 26 kDa Homo sapiens protein
Buffer: 20 mM Sodium Phosphate 150 mM NaCl 5% glycerol 3 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Nov 26
Integrin α6β4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. Structure 27(6):952-964.e6 (2019)
Manso JA, Gómez-Hernández M, Carabias A, Alonso-García N, García-Rubio I, Kreft M, Sonnenberg A, de Pereda JM
RgGuinier 2.3 nm
Dmax 8.5 nm
VolumePorod 34 nm3

SASDDP8 – Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant T1663R

UniProt ID: P16144-2 (1436-1666) Integrin beta-4 (1436-1666) T1663R
Integrin beta-4 (1436-1666) T1663R experimental SAS data
Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant T1663R Rg histogram
Sample: Integrin beta-4 (1436-1666) T1663R monomer, 26 kDa Homo sapiens protein
Buffer: 20 mM Sodium Phosphate 150 mM NaCl 5% glycerol 3 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Nov 26
Integrin α6β4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. Structure 27(6):952-964.e6 (2019)
Manso JA, Gómez-Hernández M, Carabias A, Alonso-García N, García-Rubio I, Kreft M, Sonnenberg A, de Pereda JM
RgGuinier 2.4 nm
Dmax 9.5 nm
VolumePorod 35 nm3

SASDDS8 – Neural/ectodermal development factor IMP-L2

UniProt ID: Q09024 (None-None) Neural/ectodermal development factor IMP-L2
Neural/ectodermal development factor IMP-L2 experimental SAS data
Neural/ectodermal development factor IMP-L2 Kratky plot
Sample: Neural/ectodermal development factor IMP-L2 dimer, 60 kDa Drosophila melanogaster protein
Buffer: phosphate buffered saline, pH: 7.4
Experiment: SAXS data collected at ID14-3, ESRF on 2011 Nov 20
Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones. Nat Commun 9(1):3860 (2018)
Roed NK, Viola CM, Kristensen O, Schluckebier G, Norrman M, Sajid W, Wade JD, Andersen AS, Kristensen C, Ganderton TR, Turkenburg JP, De Meyts P, Brzozowski AM
RgGuinier 3.1 nm
Dmax 12.0 nm
VolumePorod 93 nm3