Curated repository for small angle scattering data and models


SASBDB currently contains:


4995

experimental data sets

6229

models
508 experimental data sets on hold
691 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDWD7 – SEC-SAXS data of wildtype Melanotaenia fluviatilis apo estrogen receptor alpha ligand binding domain (LBD) at pH 7.5

Estrogen receptor alpha experimental SAS data
DAMMIF model
Sample: Estrogen receptor alpha dimer, 57 kDa Melanotaenia fluviatilis protein
Buffer: 20 mM Tris-HCl pH 7.5, 150 mM NaCl, 5% glycerol, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at BioSAXS, Australian Synchrotron on 2024 Nov 9
A ternary switch model governing ERĪ± ligand binding domain conformation. Nat Commun 16(1):10363 (2025)
McDougal DP, Pederick JL, Novick SJ, Jovcevski B, Warrender AK, Pascal BD, Griffin PR, Bruning JB
RgGuinier 2.5 nm
Dmax 9.2 nm
VolumePorod 72 nm3

Mammalian translation elongation factor eEF1A1
Mammalian translation elongation factor eEF1A1 experimental SAS data
Dynamics and structural features of the eEF1A1 and eEF1A2 paralogs Nucleic Acids Research 2025 Nov 13 53(21)
Nucleic Acids Research 53(21) (2025 Nov 13)
Entamoeba histolytica Anti-Silencing Function 1 (ASF1) with C terminal His6-tag
Anti-Silencing Function 1 experimental SAS data
Characterisation of Entamoeba histolytica Anti-Silencing Function 1 as a histone chaperone. Biochimie 2025 Nov 11;
Biochimie (2025 Nov 11)
N-acetylmuramoyl-L-alanine amidase (without His-Tag)
N-acetylmuramoyl-L-alanine amidase experimental SAS data
Dissecting the molecular basis underlying mycobacterial cell-wall hydrolysis by the catalytic domains of D29LysA and DS6ALysA phage endolysins. Int J Biol Macromol 2025 Nov 7;:148896
Int J Biol Macromol :148896 (2025 Nov 7)
K214/R260 mutant of Rabies virus CVS Phosphoprotein Isoform 3 (KRm CVS P3)
Phosphoprotein (Isoform P3; K214A, R260A, D289N, C297S) experimental SAS data
Conformational dynamics, RNA binding, and phase separation regulate the multifunctionality of rabies virus P protein. Nat Commun 2025 Oct 29;16(1):9491
Nat Commun 16(1):9491 (2025 Oct 29)
Mutual gliding motility protein C and B interacting with the C-terminal helix of RomR protein from Myxococcus xanthus
Two-component system response regulatorMutual gliding motility protein CGliding motility protein MglB experimental SAS data
Structural and biophysical insights into RomR, MglB and MglC interactions involved in regulating cell polarity in Myxococcus xanthus Journal of Biological Chemistry 2025 Nov :110907
Journal of Biological Chemistry :110907 (2025 Nov)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.