Curated repository for small angle scattering data and models


SASBDB currently contains:


5002

experimental data sets

6249

models
510 experimental data sets on hold
682 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDV33 – N-terminal domain construct of hsGEFH1_190-582aa fit to DAMMIF and Alphafold2 models

Isoform 1 of Rho guanine nucleotide exchange factor 2 experimental SAS data
ALPHAFOLD model
Sample: Isoform 1 of Rho guanine nucleotide exchange factor 2 monomer, 47 kDa Homo sapiens protein
Buffer: 20mM Tris-Cl, 150mM NaCl, 1mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2021 Feb 19
Structural basis of microtubule-mediated signal transduction. Cell (2025)
Choi SR, Blum TB, Giono M, Roy B, Vakonakis I, Schmid D, Oelgarth N, Ranganathan A, Gossert AD, Shivashankar GV, Zippelius A, Steinmetz MO
RgGuinier 5.9 nm

Enabled/vasodilator-stimulated phosphoprotein homology 1 domain (EVH1) from Mus musculus Homer1
EVH1 domain of Homer protein homolog 1 from mouse experimental SAS data
Structural Modeling and Dynamics of the Full-Length Homer1 Multimer. Proteins 2025 Nov 21;
Proteins (2025 Nov 21)
Group IIC intron Domain 1 & 2
Group IIC Intron Domain 1 & 2 experimental SAS data
Dynamic assembly of a large multidomain ribozyme visualized by cryo-electron microscopy. Nat Commun 2025 Nov 27;16(1):10195
Nat Commun 16(1):10195 (2025 Nov 27)
SEC-SAXS data of wildtype Melanotaenia fluviatilis apo estrogen receptor alpha ligand binding domain (LBD) at pH 7.5
Estrogen receptor alpha experimental SAS data
A ternary switch model governing ERα ligand binding domain conformation. Nat Commun 2025 Nov 24;16(1):10363
Nat Commun 16(1):10363 (2025 Nov 24)
Mammalian translation elongation factor eEF1A1
Mammalian translation elongation factor eEF1A1 experimental SAS data
Dynamics and structural features of the eEF1A1 and eEF1A2 paralogs Nucleic Acids Research 2025 Nov 13 53(21)
Nucleic Acids Research 53(21) (2025 Nov 13)
Entamoeba histolytica Anti-Silencing Function 1 (ASF1) with C terminal His6-tag
Anti-Silencing Function 1 experimental SAS data
Characterisation of Entamoeba histolytica Anti-Silencing Function 1 as a histone chaperone. Biochimie 2025 Nov 11;
Biochimie (2025 Nov 11)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.