Browse by MODEL: Ab initio only

SASDXC2 – EGFR kinase domain duplication mutant (KDD) at 1.6 mg/ml

Receptor protein-tyrosine kinase (duplication mutant) experimental SAS data
DAMMIF model
Sample: Receptor protein-tyrosine kinase (duplication mutant) monomer, 80 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 250 mM NaCl, 250 mM KCl, pH: 8
Experiment: SAXS data collected at Rigaku MicroMax-007HF, Yale University on 2022 Mar 22
The role of kinase domain dimerization in EGFR activation
Zaritza Petrova
RgGuinier 3.9 nm
Dmax 13.0 nm
VolumePorod 135 nm3

SASDXP4 – Mutual gliding motility protein C from Myxococcus xanthus

Mutual gliding motility protein C experimental SAS data
GASBOR model
Sample: Mutual gliding motility protein C dimer, 32 kDa Myxococcus xanthus (strain … protein
Buffer: 20 mM HEPES, 150 mM NaCl, 10% glycerol, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2023 Mar 31
Structural and biophysical insights into RomR, MglB and MglC interactions involved in regulating cell polarity in Myxococcus xanthus Journal of Biological Chemistry :110907 (2025)
Kodesia A, Kapoor S, Thakur K
RgGuinier 2.3 nm
Dmax 9.8 nm
VolumePorod 49 nm3

SASDXU4 – Mutual gliding motility protein C and B interacting with the C-terminal helix of RomR protein from Myxococcus xanthus

Two-component system response regulatorMutual gliding motility protein CGliding motility protein MglB experimental SAS data
SREFLEX model
Sample: Two-component system response regulator trimer, 26 kDa Myxococcus xanthus DK … protein
Mutual gliding motility protein C dimer, 32 kDa Myxococcus xanthus (strain … protein
Gliding motility protein MglB dimer, 32 kDa Myxococcus xanthus (strain … protein
Buffer: 20 mM HEPES, 150 mM NaCl, 10% glycerol, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2023 Mar 31
Structural and biophysical insights into RomR, MglB and MglC interactions involved in regulating cell polarity in Myxococcus xanthus Journal of Biological Chemistry :110907 (2025)
Kodesia A, Kapoor S, Thakur K
RgGuinier 3.8 nm
Dmax 13.6 nm
VolumePorod 204 nm3

SASDTK3 – Human aryl-hydrocarbon receptor-interacting protein (R9Q point mutant)

AH receptor-interacting protein (R9Q) experimental SAS data
OTHER model
Sample: AH receptor-interacting protein (R9Q) monomer, 39 kDa Homo sapiens protein
Buffer: 20 mM Tris-Cl pH 7.5, 100 mM NaCl, 1 mM DTT, 5% (v/v) glycerol, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2018 Jun 13
Human AIP HSP90 complex
Robert Rambo
RgGuinier 3.0 nm
Dmax 10.9 nm
VolumePorod 64 nm3

SASDV69 – Mouse Central Communication Network 2 (N-terminal Fragment)

Cellular communication network factor 2 experimental SAS data
Sample: Cellular communication network factor 2 monomer, 36 kDa protein
Buffer: 50 mM Tris pH 7.5, 200 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 May 6
Structural basis for therapeutic antibody binding to CCN2 and its mechanisms on TGF-β family signaling
Haben Gabir
RgGuinier 2.1 nm
Dmax 7.1 nm
VolumePorod 29 nm3

SASDV79 – Mouse Central Communication Network 2 (CCN2) in complex with anti-CCN2 F(ab) antibody 37-45-MH1

Cellular communication network factor 2anti-CCN2 37-45-MH1 F(ab) antibody experimental SAS data
Sample: Cellular communication network factor 2 monomer, 36 kDa protein
Anti-CCN2 37-45-MH1 F(ab) antibody monomer, 49 kDa protein
Buffer: 50 mM Tris pH 7.5, 200 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 May 6
Structural basis for therapeutic antibody binding to CCN2 and its mechanisms on TGF-β family signaling
Haben Gabir
RgGuinier 3.3 nm
Dmax 11.9 nm
VolumePorod 95 nm3

SASDV88 – Mycobacterium tuberculosis UvrA2.UvrB2 complex

UvrABC system protein AUvrABC system protein B experimental SAS data
GASBOR model
Sample: UvrABC system protein A dimer, 212 kDa Mycobacterium tuberculosis (strain … protein
UvrABC system protein B dimer, 161 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 50 mM Tris pH 8, 200 mM NaCl, 2% glycerol, pH:
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2022 Jun 6
The UvrA2B2 pre-initiation complex from the Nucleotide Excision Repair pathway of Mycobacterium tuberculosis.
farheen jahan
RgGuinier 5.3 nm
Dmax 15.8 nm
VolumePorod 1053 nm3

SASDXM8 – Disordered repeats-in-toxin domain Block V of Bifunctional hemolysin/adenylate cyclase

Repeats-in-toxin domain Block V of adenylate cyclase toxin experimental SAS data
Sample: Repeats-in-toxin domain Block V of adenylate cyclase toxin monomer, 19 kDa Bordetella pertussis protein
Buffer: 50 mM Tris, 5 mM DTT, pH: 7.5
Experiment: SAXS data collected at BL4-2, Stanford Synchrotron Radiation Lightsource (SSRL) on 2024 Apr 1
Ion-selective conformational stabilization of a disordered repeats-in-toxin protein domain. Biophys J (2025)
Gudinas AP, Shambharkar GM, Chang MP, Fernández D, Matsui T, Mai DJ
RgGuinier 3.7 nm
Dmax 15.4 nm
VolumePorod 52 nm3

SASDXN8 – Repeats-in-toxin domain Block V of Bifunctional hemolysin/adenylate cyclase, 1 mM CaCl2

Repeats-in-toxin domain Block V of adenylate cyclase toxin experimental SAS data
Sample: Repeats-in-toxin domain Block V of adenylate cyclase toxin monomer, 19 kDa Bordetella pertussis protein
Buffer: 50 mM Tris, 5 mM DTT, 1 mM CaCl2, pH: 7.5
Experiment: SAXS data collected at BL4-2, Stanford Synchrotron Radiation Lightsource (SSRL) on 2024 Jun 28
Ion-selective conformational stabilization of a disordered repeats-in-toxin protein domain. Biophys J (2025)
Gudinas AP, Shambharkar GM, Chang MP, Fernández D, Matsui T, Mai DJ
RgGuinier 2.0 nm
Dmax 8.1 nm
VolumePorod 38 nm3

SASDXQ8 – Repeats-in-toxin domain Block V of Bifunctional hemolysin/adenylate cyclase, 1 mM MgCl2

Repeats-in-toxin domain Block V of adenylate cyclase toxin experimental SAS data
Sample: Repeats-in-toxin domain Block V of adenylate cyclase toxin monomer, 19 kDa Bordetella pertussis protein
Buffer: 50 mM Tris, 5 mM DTT, 1 mM MgCl2, pH: 7.5
Experiment: SAXS data collected at BL4-2, Stanford Synchrotron Radiation Lightsource (SSRL) on 2024 Jun 28
Ion-selective conformational stabilization of a disordered repeats-in-toxin protein domain. Biophys J (2025)
Gudinas AP, Shambharkar GM, Chang MP, Fernández D, Matsui T, Mai DJ
RgGuinier 3.5 nm
Dmax 14.9 nm
VolumePorod 49 nm3