Browse by MODEL: Ab initio only

SASDQR8 – Exon1 of Non pathogenic form of Huntingtin (H16) with GFP fused at the C-terminus

Huntingtin experimental SAS data
OTHER [STATIC IMAGE] model
Sample: Huntingtin monomer, 39 kDa Homo sapiens protein
Buffer: 20mM BisTris-HCl, 150mM NaCl, pH: 6.5
Experiment: SAXS data collected at SWING, SOLEIL on 2019 Dec 3
The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity. Nat Struct Mol Biol (2023)
Elena-Real CA, Sagar A, Urbanek A, Popovic M, Morató A, Estaña A, Fournet A, Doucet C, Lund XL, Shi ZD, Costa L, Thureau A, Allemand F, Swenson RE, Milhiet PE, Crehuet R, Barducci A, Cortés J, Sinnaeve D, Sibille N, Bernadó P
RgGuinier 3.3 nm
Dmax 16.0 nm
VolumePorod 63 nm3

SASDQS8 – Exon1 of Pathogenic form of Huntingtin (H46) with GFP fused at the C-terminus

Huntingtin experimental SAS data
OTHER [STATIC IMAGE] model
Sample: Huntingtin monomer, 43 kDa Homo sapiens protein
Buffer: 20mM BisTris-HCl, 150mM NaCl, pH: 6.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Oct 28
The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity. Nat Struct Mol Biol (2023)
Elena-Real CA, Sagar A, Urbanek A, Popovic M, Morató A, Estaña A, Fournet A, Doucet C, Lund XL, Shi ZD, Costa L, Thureau A, Allemand F, Swenson RE, Milhiet PE, Crehuet R, Barducci A, Cortés J, Sinnaeve D, Sibille N, Bernadó P
RgGuinier 4.2 nm

SASDP64 – SALL4 Zinc Finger Cluster 4

Sal-like protein 4 experimental SAS data
DAMMIN model
Sample: Sal-like protein 4 monomer, 8 kDa Mus musculus protein
Buffer: 20 mM Tris-HCl, pH 7.5, 200 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2020 Feb 6
Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome. Life Sci Alliance 6(3) (2023)
Watson JA, Pantier R, Jayachandran U, Chhatbar K, Alexander-Howden B, Kruusvee V, Prendecki M, Bird A, Cook AG
RgGuinier 2.1 nm
Dmax 5.8 nm
VolumePorod 11 nm3

SASDP84 – SALL4 Zinc Finger Cluster 4 bound to AT-rich DNA

Sal-like protein 4AT-rich dsDNA experimental SAS data
OTHER model
Sample: Sal-like protein 4 monomer, 8 kDa Mus musculus protein
AT-rich dsDNA monomer, 7 kDa DNA
Buffer: 20 mM Tris-HCl, pH 7.5, 200 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2020 Feb 6
Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome. Life Sci Alliance 6(3) (2023)
Watson JA, Pantier R, Jayachandran U, Chhatbar K, Alexander-Howden B, Kruusvee V, Prendecki M, Bird A, Cook AG
RgGuinier 1.8 nm
Dmax 5.1 nm
VolumePorod 14 nm3

SASDQE5 – Nucleoside triphosphate pyrophosphohydrolase (1–185)

Nucleoside triphosphate pyrophosphohydrolase experimental SAS data
DAMMIF model
Sample: Nucleoside triphosphate pyrophosphohydrolase dimer, 41 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM Tris-HCl, 100 mM NaCl, pH: 7.5
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2020 Dec 11
Structural analysis of the housecleaning nucleoside triphosphate pyrophosphohydrolase MazG from Mycobacterium tuberculosis Frontiers in Microbiology 14 (2023)
Wang S, Gao B, Chen A, Zhang Z, Wang S, Lv L, Zhao G, Li J
RgGuinier 2.7 nm
Dmax 8.4 nm
VolumePorod 64 nm3

SASDQ38 – Nucleoside triphosphate pyrophosphohydrolase (full-length)

Nucleoside triphosphate pyrophosphohydrolase experimental SAS data
DAMMIF model
Sample: Nucleoside triphosphate pyrophosphohydrolase dimer, 71 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM Tris-HCl, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2022 Sep 4
Structural analysis of the housecleaning nucleoside triphosphate pyrophosphohydrolase MazG from Mycobacterium tuberculosis Frontiers in Microbiology 14 (2023)
Wang S, Gao B, Chen A, Zhang Z, Wang S, Lv L, Zhao G, Li J
RgGuinier 3.4 nm
Dmax 12.2 nm
VolumePorod 121 nm3

SASDQB9 – YdaT_toxin domain-containing protein

YdaT_toxin domain-containing protein experimental SAS data
OTHER [STATIC IMAGE] model
Sample: YdaT_toxin domain-containing protein tetramer, 74 kDa Escherichia coli O157:H7 protein
Buffer: 20 mM Tris-HCl, 200 mM NaCl, pH: 8
Experiment: SAXS data collected at SWING, SOLEIL on 2022 Apr 16
Structural basis of DNA binding by YdaT, a functional equivalent of the CII repressor in the cryptic prophage CP-933P from Escherichia coli O157:H7 Acta Crystallographica Section D Structural Biology 79(3):245-258 (2023)
Prolič-Kalinšek M, Volkov A, Hadži S, Van Dyck J, Bervoets I, Charlier D, Loris R
RgGuinier 3.5 nm
Dmax 12.0 nm
VolumePorod 130 nm3

SASDQC9 – Mutant YdaT_toxin domain-containing protein (L111N/F118R)

YdaT_toxin domain-containing protein (mutant: L111N, F118R) experimental SAS data
OTHER [STATIC IMAGE] model
Sample: YdaT_toxin domain-containing protein (mutant: L111N, F118R) monomer, 18 kDa Escherichia coli O157:H7 protein
Buffer: 20 mM Tris-HCl, 200 mM NaCl, pH: 8
Experiment: SAXS data collected at SWING, SOLEIL on 2021 Apr 14
Structural basis of DNA binding by YdaT, a functional equivalent of the CII repressor in the cryptic prophage CP-933P from Escherichia coli O157:H7 Acta Crystallographica Section D Structural Biology 79(3):245-258 (2023)
Prolič-Kalinšek M, Volkov A, Hadži S, Van Dyck J, Bervoets I, Charlier D, Loris R
RgGuinier 2.4 nm
Dmax 8.2 nm
VolumePorod 32 nm3

SASDQD9 – N-terminal domain of YdaT_toxin domain-containing protein

YdaT_toxin domain-containing protein experimental SAS data
OTHER [STATIC IMAGE] model
Sample: YdaT_toxin domain-containing protein monomer, 13 kDa Escherichia coli O157:H7 protein
Buffer: 20 mM Tris-HCl, 200 mM NaCl, pH: 8
Experiment: SAXS data collected at SWING, SOLEIL on 2022 Apr 16
Structural basis of DNA binding by YdaT, a functional equivalent of the CII repressor in the cryptic prophage CP-933P from Escherichia coli O157:H7 Acta Crystallographica Section D Structural Biology 79(3):245-258 (2023)
Prolič-Kalinšek M, Volkov A, Hadži S, Van Dyck J, Bervoets I, Charlier D, Loris R
RgGuinier 1.7 nm
Dmax 5.7 nm
VolumePorod 29 nm3

SASDWG7 – D52A mutant of ferric binding protein (FbpA) in apo (no Fe) form in low ionic strength (LIS) buffer (1/10 PBS)

Iron-utilization periplasmic protein experimental SAS data
DAMFILT model
Sample: Iron-utilization periplasmic protein monomer, 34 kDa Haemophilus influenzae protein
Buffer: 1 mM Na2HPO4.7H2O, 0.18 mM KH2PO4, 13.7 mM NaCl, 0.27 mM KCl, 5%v/v Glycerol, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Aug 20
Conformational multiplicity of bacterial ferric binding protein revealed by small angle x-ray scattering and molecular dynamics calculations The Journal of Chemical Physics 158(8) (2023)
Liu G, Ekmen E, Jalalypour F, Mertens H, Jeffries C, Svergun D, Atilgan A, Atilgan C, Sayers Z
RgGuinier 2.1 nm
Dmax 6.3 nm
VolumePorod 28 nm3