Browse by MODEL: Hybrid

SASDSW6 – Palivizumab Nanobody AIP1VHH complex

Palivizumab IgGAnti-Idiotypic-Palivizumab-Nanobody1 experimental SAS data
CORAL model
Sample: Palivizumab IgG monomer, 145 kDa Commercial (Synagis) protein
Anti-Idiotypic-Palivizumab-Nanobody1 monomer, 20 kDa Lama glama protein
Buffer: PBS (137 mM NaCl, 2.7 mM KCl, 12 mM HPO4 2−/H2PO4 −), pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Sep 14
Respiratory syncytial virus (RSV)-approved monoclonal antibody Palivizumab as ligand for anti-idiotype nanobody-based synthetic cytokine receptors Journal of Biological Chemistry :105270 (2023)
Ettich J, Wittich C, Moll J, Behnke K, Floss D, Reiners J, Christmann A, Lang P, Smits S, Kolmar H, Scheller J
RgGuinier 6.0 nm
Dmax 20.4 nm

SASDKP7 – Probable transcriptional regulatory protein Lrp/AsnC protein Rv2324

Probable transcriptional regulatory protein (Probably AsnC-family) experimental SAS data
DAMMIF model
Sample: Probable transcriptional regulatory protein (Probably AsnC-family) dimer, 36 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM Tris, 150 mM NaCl, 2 mM EDTA, pH: 7.5
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2019 Mar 1
Mycobacterium tuberculosis Rv2324 is a multifunctional feast/famine regulatory protein involved in growth, DNA replication and damage control. Int J Biol Macromol 252:126459 (2023)
Dubey S, Maurya RK, Shree S, Kumar S, Jahan F, Krishnan MY, Ramachandran R
RgGuinier 2.7 nm
Dmax 11.6 nm
VolumePorod 156 nm3

SASDKQ7 – Probable transcriptional regulatory protein Lrp/AsnC protein Rv2324 in the presence of methionine

Probable transcriptional regulatory protein (Probably AsnC-family) experimental SAS data
DAMMIF model
Sample: Probable transcriptional regulatory protein (Probably AsnC-family) octamer, 143 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM Tris, 150 mM NaCl, 2 mM EDTA, 2 mM methionine, pH: 7.5
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2019 Dec 5
Mycobacterium tuberculosis Rv2324 is a multifunctional feast/famine regulatory protein involved in growth, DNA replication and damage control. Int J Biol Macromol 252:126459 (2023)
Dubey S, Maurya RK, Shree S, Kumar S, Jahan F, Krishnan MY, Ramachandran R
RgGuinier 4.0 nm
Dmax 13.8 nm
VolumePorod 246 nm3

SASDSX6 – Aquifex aeolicus domain of unknown function 507 at 1 mg/mL

DUF507 family protein experimental SAS data
CUSTOM IN-HOUSE model
Sample: DUF507 family protein monomer, 22 kDa Aquifex aeolicus (strain … protein
Buffer: 20 mM Hepes pH 7.2, 400 mM NaCl, pH: 7.2
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Dec 7
Crystal structure of domain of unknown function 507 (DUF507) reveals a new protein fold. Sci Rep 13(1):13496 (2023)
McKay CE, Cheng J, Tanner JJ
RgGuinier 2.3 nm
Dmax 9.0 nm
VolumePorod 39 nm3

SASDJB6 – Lactococcus phage Phi28 apo-gp11 encapsidation protein

gp11 encapsidation protein experimental SAS data
OTHER model
Sample: Gp11 encapsidation protein decamer, 446 kDa Lactococcus phage Phi28 protein
Buffer: 100 mM NaCl, 25 mM HEPES, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-1000, Sealy Center For Structural Biology, UTMB-G on 2015 May 6
Lactococcus Phage ASCC Phi28 gp11
Mark White
RgGuinier 5.3 nm
Dmax 16.3 nm

SASDRC3 – Homo-oligomeric mixture of human myelin protein zero Ig domain

Myelin protein P0 experimental SAS data
ALPHAFOLD model
Sample: Myelin protein P0, 15 kDa Homo sapiens protein
Buffer: 50 mM NaCl, 1 mM EDTA, 20 mM TrisCl, pH: 7.6
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2021 Jul 21
Homomeric interactions of the MPZ Ig domain and their relation to Charcot-Marie-Tooth disease Brain (2023)
Ptak C, Peterson T, Hopkins J, Ahern C, Shy M, Piper R
RgGuinier 2.9 nm
Dmax 17.0 nm

SASDRD3 – Homo-oligomeric mixture of human myelin protein zero Ig domain (W53A, R74A, D75R mutant)

Myelin protein P0 (W53A, R74A, D75R) experimental SAS data
ALPHAFOLD model
Sample: Myelin protein P0 (W53A, R74A, D75R), 14 kDa Homo sapiens protein
Buffer: 50 mM NaCl, 1 mM EDTA, 20 mM TrisCl, pH: 7.6
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Jul 14
Homomeric interactions of the MPZ Ig domain and their relation to Charcot-Marie-Tooth disease Brain (2023)
Ptak C, Peterson T, Hopkins J, Ahern C, Shy M, Piper R
RgGuinier 1.9 nm
Dmax 7.0 nm

SASDM55 – GTP-binding domain of Candida albicans Ras-like protein 1

GTP-binding domain of Ras-like protein 1 experimental SAS data
MODELLER model
Sample: GTP-binding domain of Ras-like protein 1 monomer, 19 kDa protein
Buffer: 20 mM Tris-HCl, 150 mM NaCl, 5% glycerol, 3 mM DTT, 5 mM MgCl2, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Jun 21
Pathogen-specific structural features of Candida albicans Ras1 activation complex: uncovering new antifungal drug targets. mBio :e0063823 (2023)
Manso JA, Carabias A, Sárkány Z, de Pereda JM, Pereira PJB, Macedo-Ribeiro S
RgGuinier 1.6 nm
Dmax 4.1 nm
VolumePorod 26 nm3

SASDM75 – Ras-like protein 1 guanine nucleotide exchange factor region of Candida albicans cell division control protein 25

Cell division control protein 25 experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Cell division control protein 25 monomer, 55 kDa Candida albicans (strain … protein
Buffer: 20 mM Na-phosphate, 150 mM NaCl, 5% glycerol, 3 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Jun 21
Pathogen-specific structural features of Candida albicans Ras1 activation complex: uncovering new antifungal drug targets. mBio :e0063823 (2023)
Manso JA, Carabias A, Sárkány Z, de Pereda JM, Pereira PJB, Macedo-Ribeiro S
RgGuinier 3.2 nm
Dmax 11.8 nm
VolumePorod 81 nm3

SASDM85 – GTP-binding domain of Candida albicans Ras-like protein 1 in complex with the guanine nucleotide exchange factor region of cell division control protein 25

GTP-binding domain of Ras-like protein 1Cell division control protein 25 experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: GTP-binding domain of Ras-like protein 1 monomer, 19 kDa protein
Cell division control protein 25 monomer, 55 kDa Candida albicans (strain … protein
Buffer: 20 mM Na-phosphate, 150 mM NaCl, 1 mM EDTA, 5% glycerol, 3 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Jun 21
Pathogen-specific structural features of Candida albicans Ras1 activation complex: uncovering new antifungal drug targets. mBio :e0063823 (2023)
Manso JA, Carabias A, Sárkány Z, de Pereda JM, Pereira PJB, Macedo-Ribeiro S
RgGuinier 3.2 nm
Dmax 11.8 nm
VolumePorod 99 nm3