Browse by MODEL: No model

SASDX95 – DNA repair protein RAD51 homolog 1 (RAD51) [F86E, A89E] in complex with Breast cancer type 2 susceptibility protein (BRCA2) truncation containing the second, third and fourth BRC repeats (BRC2-4) at 1 mg/mL

Breast cancer type 2 susceptibility protein (BRC repeats 2-4)DNA repair protein RAD51 homolog 1 (F86E A89E) experimental SAS data
Breast cancer type 2 susceptibility protein (BRC repeats 2-4) DNA repair protein RAD51 homolog 1 (F86E A89E) Kratky plot
Sample: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) monomer, 39 kDa Homo sapiens protein
DNA repair protein RAD51 homolog 1 (F86E A89E) trimer, 111 kDa Homo sapiens protein
Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Dec 2
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 6.5 nm
Dmax 28.5 nm
VolumePorod 334 nm3

SASDXA5 – DNA repair protein RAD51 homolog 1 (RAD51) [F86E, A89E] in complex with Breast cancer type 2 susceptibility protein (BRCA2) truncation containing the second, third and fourth BRC repeats (BRC2-4) at 2 mg/mL

Breast cancer type 2 susceptibility protein (BRC repeats 2-4)DNA repair protein RAD51 homolog 1 (F86E A89E) experimental SAS data
Breast cancer type 2 susceptibility protein (BRC repeats 2-4) DNA repair protein RAD51 homolog 1 (F86E A89E) Kratky plot
Sample: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) monomer, 39 kDa Homo sapiens protein
DNA repair protein RAD51 homolog 1 (F86E A89E) trimer, 111 kDa Homo sapiens protein
Buffer: 20 mM K₂HPO₄/KH₂PO₄, 100 mM NaCl, 200 mM Li₂SO₄, 5% glycerol, 1 mM DTT, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Dec 2
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 6.5 nm
Dmax 28.5 nm
VolumePorod 473 nm3

SASDXB5 – DNA repair protein RAD51 homolog 1 (RAD51) [F86E, A89E] in complex with Breast cancer type 2 susceptibility protein (BRCA2) truncation containing the second, third and fourth BRC repeats (BRC2-4) at 3.5 mg/mL

Breast cancer type 2 susceptibility protein (BRC repeats 2-4)DNA repair protein RAD51 homolog 1 (F86E A89E) experimental SAS data
Breast cancer type 2 susceptibility protein (BRC repeats 2-4) DNA repair protein RAD51 homolog 1 (F86E A89E) Kratky plot
Sample: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) monomer, 39 kDa Homo sapiens protein
DNA repair protein RAD51 homolog 1 (F86E A89E) trimer, 111 kDa Homo sapiens protein
Buffer: 20 mM Hepes, 350 mM KCl, 1 mM DTT, 5% Glycerol, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Dec 4
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 6.9 nm
Dmax 28.5 nm
VolumePorod 652 nm3

SASDXC5 – DNA repair protein RAD51 homolog 1 (RAD51) [F86E, A89E] in complex with Breast cancer type 2 susceptibility protein (BRCA2) truncation containing the second, third and fourth BRC repeats (BRC2-4) at 7 mg/mL

Breast cancer type 2 susceptibility protein (BRC repeats 2-4)DNA repair protein RAD51 homolog 1 (F86E A89E) experimental SAS data
Breast cancer type 2 susceptibility protein (BRC repeats 2-4) DNA repair protein RAD51 homolog 1 (F86E A89E) Kratky plot
Sample: Breast cancer type 2 susceptibility protein (BRC repeats 2-4) monomer, 39 kDa Homo sapiens protein
DNA repair protein RAD51 homolog 1 (F86E A89E) trimer, 111 kDa Homo sapiens protein
Buffer: 20 mM Hepes, 350 mM KCl, 1 mM DTT, 5% Glycerol, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Dec 4
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination (2025)
Rinaldi F, Franco P, Veronesi M, Romeo E, Bresciani V, Varignani G, Catalano F, Bernetti M, Masetti M, Langer J, Girotto S, Cavalli A
RgGuinier 6.8 nm
Dmax 28.3 nm
VolumePorod 542 nm3

SASDXV4 – EGFR kinase domain duplication mutant (KDD) at 2.6 mg/ml

Receptor protein-tyrosine kinase (duplication mutant) experimental SAS data
Receptor protein-tyrosine kinase (duplication mutant) Kratky plot
Sample: Receptor protein-tyrosine kinase (duplication mutant) monomer, 80 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 250 mM NaCl, 250 mM KCl, pH: 8
Experiment: SAXS data collected at Rigaku MicroMax-007HF, Yale University on 2022 Mar 22
The role of kinase domain dimerization in EGFR activation
Zaritza Petrova
RgGuinier 4.9 nm
Dmax 16.4 nm
VolumePorod 163 nm3

SASDXW4 – EGFR kinase domain duplication mutant (KDD) at 2.7 mg/ml

Receptor protein-tyrosine kinase (duplication mutant) experimental SAS data
Receptor protein-tyrosine kinase (duplication mutant) Kratky plot
Sample: Receptor protein-tyrosine kinase (duplication mutant) monomer, 80 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 250 mM NaCl, 250 mM KCl, pH: 8
Experiment: SAXS data collected at Rigaku MicroMax-007HF, Yale University on 2022 Mar 22
The role of kinase domain dimerization in EGFR activation
Zaritza Petrova
RgGuinier 4.5 nm
Dmax 14.9 nm
VolumePorod 190 nm3

SASDXR4 – C-terminal region of RomR protein from Myxococcus xanthus

Two-component system response regulator experimental SAS data
Two-component system response regulator Kratky plot
Sample: Two-component system response regulator trimer, 39 kDa Myxococcus xanthus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 10% glycerol, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2023 Mar 31
Structural and biophysical insights into RomR, MglB and MglC interactions involved in regulating cell polarity in Myxococcus xanthus Journal of Biological Chemistry :110907 (2025)
Kodesia A, Kapoor S, Thakur K
RgGuinier 4.1 nm
Dmax 16.7 nm
VolumePorod 81 nm3

SASDXT4 – Mutual gliding motility protein C interacting with the C-terminal region of RomR protein from Myxococcus xanthus

GTPaseTwo-component system response regulator experimental SAS data
GTPase Two-component system response regulator Kratky plot
Sample: GTPase dimer, 32 kDa Myxococcus xanthus (strain … protein
Two-component system response regulator trimer, 39 kDa Myxococcus xanthus protein
Buffer: 20 mM HEPES, 150 mM NaCl, 10% glycerol, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2023 Mar 31
Structural and biophysical insights into RomR, MglB and MglC interactions involved in regulating cell polarity in Myxococcus xanthus Journal of Biological Chemistry :110907 (2025)
Kodesia A, Kapoor S, Thakur K
RgGuinier 2.5 nm
Dmax 9.1 nm
VolumePorod 79 nm3

SASDV89 – Mouse High mobility group protein B2 HMGB2-dsDNA complex

High mobility group protein B2Double stranded DNA 20mer experimental SAS data
High mobility group protein B2 Double stranded DNA 20mer Kratky plot
Sample: High mobility group protein B2 monomer, 26 kDa Mus musculus protein
Double stranded DNA 20mer monomer, 12 kDa DNA
Buffer: Tris 50mM, NaCl 150mM, pH: 7
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2024 Apr 27
High mobility group protein B2 (HMGB2)
Chun I Tu
RgGuinier 3.3 nm
Dmax 12.2 nm
VolumePorod 50 nm3

SASDVB9 – C-terminally truncated form of mouse High mobility group protein B2 (HMGB2ΔC)-dsDNA complex

High mobility group protein B2 experimental SAS data
High mobility group protein B2 Kratky plot
Sample: High mobility group protein B2 monomer, 20 kDa Mus musculus protein
Buffer: Tris 50mM, NaCl 150mM, pH: 7
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2024 Apr 27
High mobility group protein B2 (HMGB2)
Chun I Tu
RgGuinier 2.9 nm
Dmax 10.4 nm
VolumePorod 42 nm3