|
|
|
|
|
| Sample: |
Aryl hydrocarbon receptor nuclear translocator-like protein 1 monomer, 10 kDa Mus musculus protein
Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP), mutation L664C monomer, 10 kDa Mus musculus protein
|
| Buffer: |
25 mM Hepes, 150 NaCl, 1 mM DTT, 5% Glycerol, pH: 7.2 |
| Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2017 May 27
|
Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein.
J Biol Chem (2019)
Garg A, Orru R, Ye W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
|
| RgGuinier |
2.8 |
nm |
| Dmax |
11.5 |
nm |
|
|
|
|
|
|
|
| Sample: |
Brain and muscle ARNT-like 1 (G517-L625) including transactivation domain (TAD) monomer, 11 kDa Mus musculus protein
Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP) monomer, 10 kDa Mus musculus protein
|
| Buffer: |
25 mM Hepes, 150 NaCl, 1 mM DTT, 5% Glycerol, pH: 7.2 |
| Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2017 May 27
|
Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein.
J Biol Chem (2019)
Garg A, Orru R, Ye W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
|
| RgGuinier |
3.1 |
nm |
| Dmax |
13.7 |
nm |
|
|
|
|
|
|
|
| Sample: |
Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP) monomer, 10 kDa Mus musculus protein
Brain and muscle ARNT-like 1 (G490-L625) including transactivation domain (TAD) monomer, 14 kDa Mus musculus protein
|
| Buffer: |
25 mM Hepes, 150 NaCl, 1 mM DTT, 5% Glycerol, pH: 7.2 |
| Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2017 May 27
|
Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein.
J Biol Chem (2019)
Garg A, Orru R, Ye W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
|
| RgGuinier |
3.8 |
nm |
| Dmax |
17.5 |
nm |
|
|
|
|
|
|
|
| Sample: |
Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP), mutation L664C monomer, 10 kDa Mus musculus protein
1-{4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidin-1-yl}-3-sulfanylpropan-1-one monomer, 0 kDa
|
| Buffer: |
25 mM Hepes, 150 NaCl, 5% Glycerol, pH: 7.2 |
| Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2017 May 27
|
Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein.
J Biol Chem (2019)
Garg A, Orru R, Ye W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
|
| RgGuinier |
1.7 |
nm |
| Dmax |
6.4 |
nm |
|
|
|
|
|
|
|
| Sample: |
Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) monomer, 29 kDa Mus musculus protein
|
| Buffer: |
50 mM Tris-HCl, 150 mM NaCl, 2 mM TCEP, pH: 7.5 |
| Experiment: |
SAXS
data collected at BM29, ESRF on 2016 Jun 20
|
Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression.
Structure (2019)
Cordeiro TN, Sibille N, Germain P, Barthe P, Boulahtouf A, Allemand F, Bailly R, Vivat V, Ebel C, Barducci A, Bourguet W, le Maire A, Bernadó P
|
| RgGuinier |
4.7 |
nm |
| Dmax |
17.7 |
nm |
| VolumePorod |
102 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) monomer, 29 kDa Mus musculus protein
Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) monomer, 26 kDa Mus musculus protein
Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) monomer, 28 kDa Homo sapiens protein
|
| Buffer: |
50 mM Tris-HCl, 150 mM NaCl, 2 mM TCEP, pH: 7.5 |
| Experiment: |
SAXS
data collected at BM29, ESRF on 2014 Jul 23
|
Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression.
Structure (2019)
Cordeiro TN, Sibille N, Germain P, Barthe P, Boulahtouf A, Allemand F, Bailly R, Vivat V, Ebel C, Barducci A, Bourguet W, le Maire A, Bernadó P
|
| RgGuinier |
4.8 |
nm |
| Dmax |
19.4 |
nm |
| VolumePorod |
167 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) monomer, 29 kDa Mus musculus protein
Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) monomer, 26 kDa Mus musculus protein
Retinoid-X receptor alpha (RXR-alpha) Δ helix12 monomer, 24 kDa Mus musculus protein
|
| Buffer: |
50 mM Tris-HCl, 150 mM NaCl, 2 mM TCEP, pH: 7.5 |
| Experiment: |
SAXS
data collected at BM29, ESRF on 2014 Jul 23
|
Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression.
Structure (2019)
Cordeiro TN, Sibille N, Germain P, Barthe P, Boulahtouf A, Allemand F, Bailly R, Vivat V, Ebel C, Barducci A, Bourguet W, le Maire A, Bernadó P
|
| RgGuinier |
4.2 |
nm |
| Dmax |
15.7 |
nm |
| VolumePorod |
183 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) monomer, 29 kDa Mus musculus protein
Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) monomer, 26 kDa Mus musculus protein
Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) monomer, 28 kDa Homo sapiens protein
|
| Buffer: |
50 mM Tris-HCl, 150 mM NaCl, 2 mM TCEP, pH: 7.5 |
| Experiment: |
SAXS
data collected at BM29, ESRF on 2014 Jul 23
|
Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression.
Structure (2019)
Cordeiro TN, Sibille N, Germain P, Barthe P, Boulahtouf A, Allemand F, Bailly R, Vivat V, Ebel C, Barducci A, Bourguet W, le Maire A, Bernadó P
|
| RgGuinier |
4.8 |
nm |
| Dmax |
19.5 |
nm |
| VolumePorod |
178 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) monomer, 29 kDa Mus musculus protein
Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) monomer, 26 kDa Mus musculus protein
Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) mutant I396E monomer, 28 kDa Homo sapiens protein
|
| Buffer: |
50 mM Tris-HCl, 150 mM NaCl, 2 mM TCEP, pH: 7.5 |
| Experiment: |
SAXS
data collected at BM29, ESRF on 2015 Mar 9
|
Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression.
Structure (2019)
Cordeiro TN, Sibille N, Germain P, Barthe P, Boulahtouf A, Allemand F, Bailly R, Vivat V, Ebel C, Barducci A, Bourguet W, le Maire A, Bernadó P
|
| RgGuinier |
5.3 |
nm |
| Dmax |
22.4 |
nm |
| VolumePorod |
171 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) monomer, 29 kDa Mus musculus protein
Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) monomer, 26 kDa Mus musculus protein
Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) monomer, 28 kDa Homo sapiens protein
|
| Buffer: |
50 mM Tris-HCl, 150 mM NaCl, 2 mM TCEP, pH: 7.5 |
| Experiment: |
SAXS
data collected at BM29, ESRF on 2014 Jul 23
|
Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression.
Structure (2019)
Cordeiro TN, Sibille N, Germain P, Barthe P, Boulahtouf A, Allemand F, Bailly R, Vivat V, Ebel C, Barducci A, Bourguet W, le Maire A, Bernadó P
|
| RgGuinier |
4.2 |
nm |
| Dmax |
17.2 |
nm |
| VolumePorod |
131 |
nm3 |
|
|
![Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP), mutation L664C1-{4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidin-1-yl}-3-sulfanylpropan-1-one experimental SAS data](/media/intensities_files/scattering_plots/SASDF77_dat_img.png "Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP), mutation L664C1-{4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidin-1-yl}-3-sulfanylpropan-1-one experimental SAS data")
