Small Angle Scattering Biological Data Bank SASBDB

SASDMS9 – Guanidine-II Riboswitch from Escherichia coli 23mer with Mg2+

Guanidin-II riboswitch 23mer experimental SAS data

Guanidin-II riboswitch 23mer Kratky plot

Sample:	Guanidin-II riboswitch 23mer monomer, 7 kDa Escherichia coli RNA
Buffer:	25 mM potassium phosphate, 50 mM KCl, 10 mM Mg2+, pH: 6.2
Experiment:	SAXS data collected at BM29, ESRF on 2021 Feb 13

Structure and Dynamics of the Guanidine-II Riboswitch from Escherichia coli by NMR Spectroscopy and Small-angle X-ray Scattering (SAXS). Chembiochem (2021)
Schamber T, Binas O, Schlundt A, Wacker A, Schwalbe H

R_g^Guinier	1.8	nm
D_max	5.8	nm
Volume^Porod	15	nm³

SASDMT9 – Guanidine-II Riboswitch from Escherichia coli 23mer with Mg2+ and Gdn ligand

Sample:	Guanidin-II riboswitch 23mer monomer, 7 kDa Escherichia coli RNA
Buffer:	25 mM potassium phosphate, 50 mM KCl, 10 mM Mg2+, 5 mM GdnCl, pH: 6.2
Experiment:	SAXS data collected at BM29, ESRF on 2021 Feb 13

R_g^Guinier	2.2	nm
D_max	8.8	nm
Volume^Porod	19	nm³

SASDMU9 – Guanidine-II Riboswitch from Escherichia coli 49mer

Guanidin-II riboswitch 49mer experimental SAS data

Guanidin-II riboswitch 49mer Kratky plot

Sample:	Guanidin-II riboswitch 49mer dimer, 32 kDa Escherichia coli RNA
Buffer:	25 mM potassium phosphate, 50 mM KCl, pH: 6.2
Experiment:	SAXS data collected at BM29, ESRF on 2021 Feb 13

R_g^Guinier	4.1	nm
D_max	16.9	nm
Volume^Porod	56	nm³

SASDMV9 – Guanidine-II Riboswitch from Escherichia coli 49mer with Mg2+

Sample:	Guanidin-II riboswitch 49mer dimer, 32 kDa Escherichia coli RNA
Buffer:	25 mM potassium phosphate, 50 mM KCl, 10 mM Mg2+, pH: 6.2
Experiment:	SAXS data collected at BM29, ESRF on 2021 Feb 13

R_g^Guinier	4.2	nm
D_max	18.1	nm
Volume^Porod	57	nm³

SASDMW9 – Guanidine-II Riboswitch from Escherichia coli 49mer with Mg2+ and Gdn ligand

Sample:	Guanidin-II riboswitch 49mer hexamer, 95 kDa Escherichia coli RNA
Buffer:	25 mM potassium phosphate, 50 mM KCl, 10 mM Mg2+, 5 mM GdnCl, pH: 6.2
Experiment:	SAXS data collected at BM29, ESRF on 2021 Feb 13

R_g^Guinier	8.8	nm
D_max	33.6	nm
Volume^Porod	442	nm³

SASDLT2 – 6D11 IgG monoclonal antibody

Anti-prion protein monoclonal IgG2a 6D11 experimental SAS data

Sample:	Anti-prion protein monoclonal IgG2a 6D11 monomer, 145 kDa Mus musculus protein
Buffer:	phosphate buffered saline, pH: 7.4
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2019 Dec 15

Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies. Sci Adv 7(48):eabj1826 (2021)
Linsenmeier L, Mohammadi B, Shafiq M, Frontzek K, Bär J, Shrivastava AN, Damme M, Song F, Schwarz A, Da Vela S, Massignan T, Jung S, Correia A, Schmitz M, Puig B, Hornemann S, Zerr I, Tatzelt J, Biasi...

R_g^Guinier	5.1	nm
D_max	17.4	nm
Volume^Porod	330	nm³

SASDLU2 – 2:1 complex between anti prion protein monoclonal IgG 6D11 and recombinant murine prion protein

Major prion proteinAnti-prion protein monoclonal IgG2a 6D11 experimental SAS data

Sample:	Major prion protein monomer, 23 kDa Mus musculus protein Anti-prion protein monoclonal IgG2a 6D11 monomer, 145 kDa Mus musculus protein
Buffer:	phosphate buffered saline, pH: 7.4
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2019 Dec 15

R_g^Guinier	8.1	nm
D_max	24.8	nm
Volume^Porod	710	nm³

SASDK78 – E3 ubiquitin/ISG15 ligase TRIM25, apo form (TRIM25 apo)

E3 ubiquitin/ISG15 ligase TRIM25 experimental SAS data

E3 ubiquitin/ISG15 ligase TRIM25 Kratky plot

Sample:	E3 ubiquitin/ISG15 ligase TRIM25 dimer, 100 kDa Homo sapiens protein
Buffer:	20 mM MES, 75 mM NaCl, 1 mM TCEP, pH: 6.5
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2019 Nov 19

Mechanistic insights into RNA binding and RNA-regulated RIG-I ubiquitination by TRIM25
Kevin Haubrich

R_g^Guinier	6.8	nm
D_max	30.2	nm

SASDK88 – E3 ubiquitin/ISG15 ligase TRIM25 bound to pre-let-7-a-1@1 RNA (TRIM25/pre-let-7)

E3 ubiquitin/ISG15 ligase TRIM25pre-let-7-a-1@1 experimental SAS data

E3 ubiquitin/ISG15 ligase TRIM25 pre-let-7-a-1@1 Kratky plot

Sample:	E3 ubiquitin/ISG15 ligase TRIM25 dimer, 100 kDa Homo sapiens protein pre-let-7-a-1@1 monomer, 9 kDa synthetic construct RNA
Buffer:	20 mM MES, 75 mM NaCl, 1 mM TCEP, pH: 6.5
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2019 May 14

Mechanistic insights into RNA binding and RNA-regulated RIG-I ubiquitination by TRIM25
Kevin Haubrich

R_g^Guinier	5.7	nm
D_max	19.8	nm

SASDK98 – E3 ubiquitin/ISG15 ligase TRIM25 bound to pre-let-7-a-1@1 RNA (TRIM25/pre-let-7): SEC-SAXS

Sample:	E3 ubiquitin/ISG15 ligase TRIM25 dimer, 100 kDa Homo sapiens protein pre-let-7-a-1@1 monomer, 9 kDa synthetic construct RNA
Buffer:	20 mM MES, 75 mM NaCl, 1 mM TCEP, pH: 6.5
Experiment:	SAXS data collected at BM29, ESRF on 2018 Jun 4

Mechanistic insights into RNA binding and RNA-regulated RIG-I ubiquitination by TRIM25
Kevin Haubrich

R_g^Guinier	5.7	nm
D_max	23.0	nm

First << Prev Page 162 of 413 Next >> Last

4122 hits found.